trt

  1. F

    Kyzatrex Health Canada approval

    Has anyone seen any updates on Kyzatrex approval by Health Canada? All I can find is approval was expected by the end of 2025 Q2 and we are closing in on Q4
  2. madman

    Testosterone at Home: Easy Step‑by‑Step Guide to Collecting Blood with the Tasso® Device | Hims HRT Journey

    Sample collection procedure Welcome to Testosterone by Hims. Learn how to collect blood samples at home with the Tasso® device as the first step of your testosterone journey. This tutorial will show you how to draw blood safely and comfortably in about 20 minutes and seamlessly get...
  3. J

    Thinking about TRT and could use some guidance

    Hello All, Long time lurker first time poster here. First of all thanks to all the people who make this great resource available. I have had many questions answered and the information here has helped me to better formulate the questions that remain. This is a long post with a lot to unpack so...
  4. madman

    Does TRT Affect 4Kscore? New Study Reveals Surprising Impact of Testosterone on Prostate Cancer Screening

    * Our study found that men receiving TRT had significantly lower 4Kscores and PSA levels despite equivalent age and prostate volumes along with similar rates of clinically significant prostate cancer. These findings suggest that 4Kscore may be less affected by exogenous testosterone than PSA...
  5. madman

    Testosterone Deficiency After Prostate Surgery: Why Up to 1 in 3 Men Develop Low T After Radical Prostatectomy

    * TD develops in 20-30% of men within 2-4 weeks of RP, with more profound TT suppression among those with higher-grade disease (e.g., Gleason 4+3). Mechanisms include retrograde venous shunting, DVC-induced intratesticular venous pressure elevation, and pneumoperitoneum-induced testicular...
  6. C

    Less estradiol with faster-acting testosterone?

    Just putting this out for discussion and comments. There have long been anecdotal suggestions that faster-acting testosterone leads to lower overall levels of estradiol. In particular, it's often claimed in regard to using testosterone propionate versus longer esters such as cypionate. It could...
  7. S

    Giving up on TRT after 5 years

    After 5 years of HRT/TRT I'm packing it in. I now have BPH, I'm on a statin and repatha, I take cialis and an alpha blocker... testosterone and hcg, occasionally arimidex. The thing is that I didn't need any of these drugs 6 years ago before I started TRT so why am I on them now? I bought...
  8. Fernando Almaguer

    Factors Involved in Immune Resilience and Longevity

    This guys channel is fascinating. N of 1 type experimentation with diet to see how blood markers correlate with increase or decrease of certain foods. He has great guests as well. This lecture explores immune resilience, a crucial factor for health and longevity that counteracts...
  9. madman

    Uncovering Varicoceles – The Hidden Men’s Health Issue Impacting 15% of Men and Their Fertility

    In this episode, the hosts explore the often-overlooked topic of varicoceles. Dr. Justin Houman sheds light on the prevalence of this condition, affecting approximately 15% of men, and discusses the challenges in diagnosing it. Dr. Houman also delves into the significant implications varicoceles...
  10. madman

    State-of-the-Art Lecture: Updates on testosterone replacement therapy CUA 2025

    Nelson's house.....you know where it's at! Conclusions
  11. Fernando Almaguer

    NUTRITION MARKERS TO TARGET ON TRT AND WHILE AGING.

    https://lpi.oregonstate.edu/sites/lpi.oregonstate.edu/files/2025-05/top_10_public_brochure.pdf Essential Micronutrients for Healthy Aging This briefing document summarizes key information from "top_nutrients for aging well.pdf," focusing on the importance of vitamins and minerals...
  12. S

    TRT Dose question

    For those that have known me over the years know that in the past, I definitely had my struggles with TRT and I’ve tried pretty much everything there is to try. I have now been on TRT the better part of 16 years and for the last several years, I’ve been using 60 mg once per week of testosterone...
  13. M

    From enclomiphene to TRT cream - where do I stand?

    Hey all, I’ve been on topical TRT compounded cream (100 mg/day) for 52d now. No prior exogenous T before this. 50mg twice daily (AM/PM), rotating between behind knees, deltoids, and inner thighs. Chose to avoid transscrotal application as I didn't want to spike DHT/E2. I was on enclomiphene at...
  14. N

    Is it time for TRT?

    Hello all. 36 years old. Just received my bloods today and as expected low levels all across the board. I had a test 3 years ago which also showed my testosterone levels at 10.9. I have had a few symptoms for the past few years but always just put it down to working shifts and getting older...
  15. C

    What affects free testosterone under TRT?

    I’ve covered this issue in many posts, but I thought it would be helpful to put more information in one thread and expand on the topic. TL;DR: Under TRT, free testosterone is proportional to the dose rate and inversely proportional to the metabolic clearance rate. The liver accounts for most of...
  16. madman

    How Lizard Sex Transformed Medicine

    Dr. Morgentaler! * As a Harvard Medical School professor who challenged an 80-year-old Nobel Prize-winning theory, I discovered that one of medicine's most accepted beliefs about testosterone and prostate cancer was actually a dangerous myth. As a Harvard Medical School professor who...
  17. T

    Help with what to do please bloodwork

    I am now off all testosterone and these are my numbers. I felt better on 20mg a week. Not making sense to me. Curious if there's a way to fix the free and total imbalance. Any help or advice is appreciated
  18. J

    Just1Cycle.com - Improved Steroid Plotter

    Our team at Just1Cycle has built an improved version of the existing steroid plotter everyone here is familiar with. Head over to just1cycle.com to check it out. Protocol Management Track compounds: steroids, supplements, ancillaries, peptides, SARMs, and more Customize compound and ester...
  19. Btoledo85

    Testosterone SubQ

    Compound testosterone cream vs Subq injections? Which has less side effects and better results as I don’t want my rbc and hemo to shoot up blood pressure etc.
  20. Btoledo85

    Compound Cream Tingling

    I’ve started the compound testosterone cream recommended dose 150mg day started with 100mg. It’s 20% I apply to scrotum writhing minutes and lasting few hours skin feels tingly and face gets flushed any alternatives or tips ?
  21. L

    testosterone super high on 200mg

    So I just recently jumped on TRT since my levels were 269 ng/dl and i was using prescription TRT until i found a good underground lab and it was way cheaper so i switched. I figured i would get my bloodwork done and see what my test levels were at and they came back as 260.0nmol/l which is...
  22. J

    Enclomiphene on TRT for Fertility

    I think I saw a video a while back with @Nelson Vergel saying some men use Enclomiphene while on TRT and some inexplicably become fertile using that method. What are the cons of trying that? If I wanted to throw that Hail Mary, what dose of Enclomiphene should I use?
  23. SH3P

    Is DHT suppression that detrimental?

    Can't seem to really find a general consensus anywhere. Some people say DHT is important for a number of things and some say it isn't that critical after you finish developing. I started finasteride a couple of months ago, but I do not want this to be a discussion about the drug itself and its...
  24. M

    Updated Labs - Help Please

    Hey guys! I hope you're doing well. I'm reaching out because I just had some recent labs done for my annual physical/checkup through my primary care doctor, and I am genuinely surprised at the results. I posted my previous labs on another thread, and I will put them below again as well...
  25. C

    Coming off after 10 years non stop self administered "trt" MISSION IMPOSSIBLE RECOVERY

    So, firstly - I am completely aware I have a <1% chance of ever making a FULL recovery and the chances are I'm going to end up on TRT for life. But anyway - always up for a challenge and I hope this gives others who are in a similar situation some motivation. Straight to the story: Hopped on at...
  26. madman

    Unusual pulmonary embolism under TRT in male hypogonadism: a case report

    https://www.endocrine-abstracts.org/ea/0110/ea0110ep1386 Background Testosterone replacement therapy (TRT) is a well-established treatment for symptomatic hypogonadal men to maintain secondary sex characteristics and alleviate symptoms associated with testosterone deficiency. However...
  27. C

    Concerned about hair loss: TRT + deca vs TRT alone vs deca alone

    Looking for advice starting my journey. Recovering from anorexia. A physician myself but also following with a men’s health specialist. I can give labs if needed but not sure how to best run this given my history of AGA. In the past had developing AGA. got a small hair transplant and started...
  28. S

    22 yr Old Low E2, 0 Libido

    Hi Everyone, My endo recently started me on TRT - 75 mgs Test E every 5 days after finding a pituitary microadenoma causing low T. Before starting I had the whole cocktail of issues - depression, fatigue, 0 libido, ED, Restrictive eating, Binge eating, Finding no pleasure in anything. I am a...
  29. R

    Texas Premier Online Wellness Clinic

    Renewd Health empowers individuals with holistic healthcare solutions and personalized care plans. Our services include hormone replacement therapy, medical weight loss, nutritional guidance, and peptide/NAD therapy. Our experienced team ensures exceptional care in a supportive community that...
  30. madman

    Updates in testosterone therapy - Oral T combination Therapy

    * Sun explains how oral testosterone formulations—thanks to their short-acting pharmacokinetics—can preserve some endogenous testosterone production, unlike traditional injections that often completely suppress it. * He details how he customizes treatment plans by blending oral testosterone...
  31. madman

    Enabling Harmonization of your Streoid Hormone LC-MS/MS Clinical testing

    $48.83 https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ms High quality analytical methods! Got Total T or better yet FT anyone LOL! The gold satndard LC-MS/MS and Equilibrium Dialysis is where it's at BRUH! * for steroids that exhibit diurnal and age related changes...
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