trt

  1. T

    DHT Cream dosing help

    Hello, I got 10% DHT cream in lipsomal base 50ml. How much of cream do I use per day? There is no instructions or dosing. Im using it for the purpose of PFS. Im on TRT cream as well. Thanks
  2. madman

    Can You Take Testosterone and Still Have Kids? What Every Man Needs to Know

    TRT can change your hormones — but it may also shut down your sperm. In this video, Dr. Justin Houman (MD, board-certified urologist & men’s health specialist) explains how testosterone replacement therapy affects fertility, sperm count, and testicular function, how long recovery can take, and...
  3. madman

    Free vs Total Testosterone: What Most Men (and Doctors) Get Wrong

    Free testosterone vs total testosterone — which one actually matters? In this video, Dr. Justin Houman, board-certified urologist and men’s health specialist, explains the key difference between total testosterone and free testosterone, how sex hormone binding globulin (SHBG) affects your...
  4. madman

    Undecatrex™ an FDA-approved authorized generic version of Kyzatrex® is now available

    An Authorized Generic version of Kyzatrex has been approved. * An Authorized Generic is a prescription drug that is produced by a brand company under a New Drug Application (NDA) and marketed as a generic under a private label. It is identical to the branded product in appearance and has...
  5. madman

    KYZATREX® Safe for your liver: Lymphatic Absorption

    * The good news is that KYZATREX was specifically designed to be absorbed lymphatically. This means it bypasses your liver avoiding the liver toxicity associated with oral testosterone medications of the past. Kyzatrex® (testosterone undecanoate) an oral testosterone therapy Taken...
  6. madman

    Dr. Shalender Bhasin: Optimizing the Diagnosis and Treatment of Hypogonadism 2025

    Nelson's house u heard it here first! Dr. Shalender Bhasin! * over the past 4 decades he has become a global leader in the biology of androgens, sarcopenia and aging related functional decline, his research has shaped clinical guidelines, its informed public health policy particularly around...
  7. T

    Any reputable sources for DHT?

    Hello all. Im dealing with PFS symptoms from the use of finasteride. I went on TRT cream for symptom relief, but did not get much DHT related symptom relief. Looking to add DHT gel to my protocol. Anybody experienced benefits in regards to PFS symptoms with the use of DHT gel? Please advise...
  8. T

    Is my ED physical, psychological or hormonal?

    Good morning all, Hope everyone is well. I am a 33 year old man, currently weighing 88kgs and height 1.83 cm (6 foot). I have been battling erectile dysfunction for 10 years or so, starting from when I was 22 or 23 years old. I have posted about my journey in this thread (Help with...
  9. madman

    The role of testosterone in cardiovascular health: benefits and risks of replacement therapy

    * This paper examines testosterone’s dual role in the cardiovascular system. Low levels are linked to increased risks of heart failure (HF) and coronary artery disease (CAD), while testosterone replacement therapy (TRT) can improve heart function, exercise tolerance, and metabolic health...
  10. D

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I've seen that some people measure their rate of aging using tools like genetic or epigenetic clocks (e.g., DNA methylation age). I'm wondering how different testosterone dosages, from standard TRT levels up to supraphysiological doses, might affect the speed of aging as measured by these...
  11. madman

    Why Is Your Man So Tired? The Real Impact of Low Testosterone on Intimacy & Marriage

    Is your man more tired than usual, moodier, or pulling away from intimacy? You’re not imagining it. In this episode, I’m joined by Dr. Joshua Gonzalez: a board-certified urologist and sexual medicine specialist to talk about the low testosterone epidemic and why men’s midlife health is often...
  12. F

    Kyzatrex Health Canada approval

    Has anyone seen any updates on Kyzatrex approval by Health Canada? All I can find is approval was expected by the end of 2025 Q2 and we are closing in on Q4
  13. madman

    Testosterone at Home: Easy Step‑by‑Step Guide to Collecting Blood with the Tasso® Device | Hims HRT Journey

    Sample collection procedure Welcome to Testosterone by Hims. Learn how to collect blood samples at home with the Tasso® device as the first step of your testosterone journey. This tutorial will show you how to draw blood safely and comfortably in about 20 minutes and seamlessly get...
  14. J

    Thinking about TRT and could use some guidance

    Hello All, Long time lurker first time poster here. First of all thanks to all the people who make this great resource available. I have had many questions answered and the information here has helped me to better formulate the questions that remain. This is a long post with a lot to unpack so...
  15. madman

    Does TRT Affect 4Kscore? New Study Reveals Surprising Impact of Testosterone on Prostate Cancer Screening

    * Our study found that men receiving TRT had significantly lower 4Kscores and PSA levels despite equivalent age and prostate volumes along with similar rates of clinically significant prostate cancer. These findings suggest that 4Kscore may be less affected by exogenous testosterone than PSA...
  16. madman

    Testosterone Deficiency After Prostate Surgery: Why Up to 1 in 3 Men Develop Low T After Radical Prostatectomy

    * TD develops in 20-30% of men within 2-4 weeks of RP, with more profound TT suppression among those with higher-grade disease (e.g., Gleason 4+3). Mechanisms include retrograde venous shunting, DVC-induced intratesticular venous pressure elevation, and pneumoperitoneum-induced testicular...
  17. C

    Less estradiol with faster-acting testosterone?

    Just putting this out for discussion and comments. There have long been anecdotal suggestions that faster-acting testosterone leads to lower overall levels of estradiol. In particular, it's often claimed in regard to using testosterone propionate versus longer esters such as cypionate. It could...
  18. S

    Giving up on TRT after 5 years

    After 5 years of HRT/TRT I'm packing it in. I now have BPH, I'm on a statin and repatha, I take cialis and an alpha blocker... testosterone and hcg, occasionally arimidex. The thing is that I didn't need any of these drugs 6 years ago before I started TRT so why am I on them now? I bought...
  19. Fernando Almaguer

    Factors Involved in Immune Resilience and Longevity

    This guys channel is fascinating. N of 1 type experimentation with diet to see how blood markers correlate with increase or decrease of certain foods. He has great guests as well. This lecture explores immune resilience, a crucial factor for health and longevity that counteracts...
  20. madman

    Uncovering Varicoceles – The Hidden Men’s Health Issue Impacting 15% of Men and Their Fertility

    In this episode, the hosts explore the often-overlooked topic of varicoceles. Dr. Justin Houman sheds light on the prevalence of this condition, affecting approximately 15% of men, and discusses the challenges in diagnosing it. Dr. Houman also delves into the significant implications varicoceles...
  21. madman

    State-of-the-Art Lecture: Updates on testosterone replacement therapy CUA 2025

    Nelson's house.....you know where it's at! Conclusions
  22. Fernando Almaguer

    NUTRITION MARKERS TO TARGET ON TRT AND WHILE AGING.

    https://lpi.oregonstate.edu/sites/lpi.oregonstate.edu/files/2025-05/top_10_public_brochure.pdf Essential Micronutrients for Healthy Aging This briefing document summarizes key information from "top_nutrients for aging well.pdf," focusing on the importance of vitamins and minerals...
  23. S

    TRT Dose question

    For those that have known me over the years know that in the past, I definitely had my struggles with TRT and I’ve tried pretty much everything there is to try. I have now been on TRT the better part of 16 years and for the last several years, I’ve been using 60 mg once per week of testosterone...
  24. M

    From enclomiphene to TRT cream - where do I stand?

    Hey all, I’ve been on topical TRT compounded cream (100 mg/day) for 52d now. No prior exogenous T before this. 50mg twice daily (AM/PM), rotating between behind knees, deltoids, and inner thighs. Chose to avoid transscrotal application as I didn't want to spike DHT/E2. I was on enclomiphene at...
  25. N

    Is it time for TRT?

    Hello all. 36 years old. Just received my bloods today and as expected low levels all across the board. I had a test 3 years ago which also showed my testosterone levels at 10.9. I have had a few symptoms for the past few years but always just put it down to working shifts and getting older...
  26. C

    What affects free testosterone under TRT?

    I’ve covered this issue in many posts, but I thought it would be helpful to put more information in one thread and expand on the topic. TL;DR: Under TRT, free testosterone is proportional to the dose rate and inversely proportional to the metabolic clearance rate. The liver accounts for most of...
  27. madman

    How Lizard Sex Transformed Medicine

    Dr. Morgentaler! * As a Harvard Medical School professor who challenged an 80-year-old Nobel Prize-winning theory, I discovered that one of medicine's most accepted beliefs about testosterone and prostate cancer was actually a dangerous myth. As a Harvard Medical School professor who...
  28. T

    Help with what to do please bloodwork

    I am now off all testosterone and these are my numbers. I felt better on 20mg a week. Not making sense to me. Curious if there's a way to fix the free and total imbalance. Any help or advice is appreciated
  29. J

    Just1Cycle.com - Improved Steroid Plotter

    Our team at Just1Cycle has built an improved version of the existing steroid plotter everyone here is familiar with. Head over to just1cycle.com to check it out. Protocol Management Track compounds: steroids, supplements, ancillaries, peptides, SARMs, and more Customize compound and ester...
  30. Btoledo85

    Testosterone SubQ

    Compound testosterone cream vs Subq injections? Which has less side effects and better results as I don’t want my rbc and hemo to shoot up blood pressure etc.
  31. Btoledo85

    Compound Cream Tingling

    I’ve started the compound testosterone cream recommended dose 150mg day started with 100mg. It’s 20% I apply to scrotum writhing minutes and lasting few hours skin feels tingly and face gets flushed any alternatives or tips ?

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