Anastrozole dosing on Propionate

Buffbanker

New Member
Does anyone have any experience with dosing Anastrozole while on daily injections of Propionate? On Cypionate I was already taking such a low dose of Anastrozole of .0625 mg every 3.5 days. Since anastrzole’s half life is around 48 hours I could see every other day? Daily could also be used. Splitting hairs here, I know.

I’m hoping that I won’t need any and with upcoming labs I will have a better idea of estrogen management on daily Prop. Just started almost two weeks ago.
 
There's a youtube channel called "cortex labs". The guy on there is really good, not dogmatic, smart guy. He talks about Prop vs longer esters and a bunch of other things TRT/nootropics related. In some of his recent vids he addresses dosing Adex on Prop.

I think the conclusion is he needed either no E2 control at all when switching to Prop, or a tiny dose such as 0.06mg or even half of that twice/week.

Just in case, remember that even though Prop has already easily reached steady state on daily injections after two weeks, there's still probably some Cyp or Enanthate (~25%) in your blood after two weeks if you were transitioning from one of those esters.

I would wait at least another 3-4 weeks before running any tests for those longer esters to be completely out of your system and also for all your other hormones to have stabilized on the Prop, maybe even longer.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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