Excel Male Health Forum

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

24,000+ Active Members
33,000+ Discussions
20+ Years Expert Experience

Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel has spent four decades turning personal health challenges into a mission that's helped thousands of men reclaim their vitality. Diagnosed with HIV in 1985 and then creating a testosterone-based program to reverse wasting syndrome for himself and his peers, he became a pioneer in understanding how hormones affect quality of life—and has been on TRT himself for over 30 years.

A chemical engineer by training, Nelson has served as a key opinion leader for pharmaceutical companies on clinical research strategy, trained clinicians on hormone optimization protocols, and authored definitive guides including Testosterone: A Man's Guide & Beyond Testosterone. He founded DiscountedLabs.com to make lab testing accessible and built ExcelMale.com into a community where men find and share evidence-based answers.

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How to Increase Allopregnanolone, The Happiness Neurosteroid.
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DEEP DIVE: Strategies to Increase Allopregnanolone A Comprehensive Review for Mental Health Support 1. What is Allopregnanolone? Allopregnanolone (ALLO) is a neurosteroid synthesized from progesterone that acts as a potent positive allosteric...
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Palmitoylethanolamide (PEA) A Comprehensive Review of Mechanisms, Clinical Evidence, and Practical Applications January 2026 Abstract Palmitoylethanolamide (PEA) is an endogenous fatty acid amide belonging to the N-acylethanolamine family with...
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The 20 Most Influential Hair Research Studies of 2025 A Comprehensive Review of the Year's Groundbreaking Findings in Hair Loss Treatment and Research Based on Dr. Donovan's Year-End Webinar | December 29, 2025 As we close out 2025, it's an...
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Landmark Study Reveals How Different Testosterone Doses Affect Muscle, Fat, and Health Markers in Young Men A deep dive into one of the most influential studies on testosterone dosing reveals key takeaways for anyone interested in hormone...
Older Men Metabolize Testosterone More Slowly Than Young Men
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Why Older Men May Need Less Testosterone: The Surprising Science of Metabolic Clearance 1. Introduction: The Hormonal Paradox In the world of hormone replacement therapy and longevity, the prevailing assumption is often that "more is better." If...
FDA Testosterone Regulation: The Complete Guide to Label Changes, Cardiovascular Safety, and the Future of TRT Access
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FDA Testosterone Regulation: The Complete Guide to Label Changes, Cardiovascular Safety, and the Future of TRT Access Curated By Nelson Vergel | ExcelMale.com | Updated January 2026 Is testosterone replacement therapy finally being recognized...
Repatha (Evolocumab) Effects on Coronary Artery Calcium (CAC) Scoring and CCTA
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Prepared: January 2026, Curated by Nelson Vergel Key Finding: Evolocumab induces significant coronary plaque regression and stabilization but does not differentially affect coronary calcium accumulation compared to statin monotherapy. However...
Coronary Artery Calcium (CAC) scoring and Coronary Computed Tomographic Angiography (CCTA) in Men with Low Testosterone
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Diagnostic Assessment Strategy: Cardiovascular Risk & Systemic Health in Hypogonadal Patients 1. Strategic Framework for Cardiovascular Risk in the Hypogonadal Male In the contemporary clinical landscape, the management of the hypogonadal male...
Exercise for Men on Testosterone Replacement Therapy: The Complete Guide to Building Muscle and Losing Fat
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Introduction: Why Exercise Matters More on TRT Are you getting the most out of your testosterone replacement therapy? For many men on TRT, the answer is no—and the missing link is often a properly designed exercise program. While testosterone...
The Testobolome: How Your Gut Bacteria Control Your Testosterone
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What You Need to Know Scientists have discovered that the trillions of bacteria living in your gut don't just help you digest food—they also control how much testosterone your body has available to use. They're calling this system the...
L-Carnitine and CoQ10 for Male Fertility: Positive Placebo-Controlled Study Results
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L-Carnitine and CoQ10 for Male Fertility: The Complete Evidence-Based Guide to Improving Sperm Quality Curated By Nelson Vergel | ExcelMale.com | Updated January 2026 Introduction Could a simple combination of two naturally occurring compounds...
The Psychedelic Medicine Pipeline 2026
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The psychedelic drug development landscape has reached an inflection point in early 2026, with Compass Pathways achieving the first positive Phase 3 psilocybin trial results in June 2025, while Lykos Therapeutics' MDMA rejection has reshaped...

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