Men's Health

Estrogen-It's what makes a real man
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Study: Low estrogen can cause problems for men Study: Low estrogen can cause problems for men (2013) Dr. Joel Finkelstein, an endocrinologist at Harvard Medical School and the lead author of a new study, talks about the effects of declining...
Metabolic benefits afforded by estradiol and testosterone in both sexes
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As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones...
Testosterone and Atrial Fibrillation
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11:25-12:50 * It is likely a U shape therapeutic curve with the lowest incidence of occuring at men with mid-range values of concentrations (350-550 ng/dL) Testosterone Therapy and Cardiovascular Risk: Insights from an Interventional...
Can Clomiphene / Enclomiphene Reverse Testicular Atrophy? Review of Limited Data.
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Below is a synthesis of what the literature presently shows about clomiphene (and its trans-isomer enclomiphene) and reversal of testicular atrophy in men. What hard data exist? Setting Study design (n) Testicular-volume result Time to...
Why Use hCG With TRT?- A Clinical Review
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Using hCG in Men on Testosterone Replacement Therapy (TRT) – A Clinical Review Introduction Exogenous testosterone replacement therapy (TRT) can profoundly suppress the hypothalamic-pituitary-gonadal (HPG) axis through negative feedback. By...
The Evolution of Testosterone Products in the U.S. (1935-2025)
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Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early...
Deca Gains. What to expect
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Doc just prescribed me 100mg weekly of Deca for joint pain and a bad shoulder. my current protocol is Test Cyp 180mg weekly (pin eod). I am a seasoned lifter. 38 years old. about 12% bf. Pull 500 pound deadlifts for reps. Since starting TRT...
Shifting the Testosterone Treatment Paradigm with Oral Testosterone (Kyzatrex)
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Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape...

Postorgasmic Illness Syndrome: An Update

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Briefing Document: Postorgasmic Illness Syndrome (POIS) Source: (Zizzo, Sávio, Ramasamy, Lima, 2022) I. Executive Summary Postorgasmic Illness Syndrome (POIS) is a rare and poorly understood condition primarily affecting men, characterized by a...
Testosterone Replacement Therapy (TRT) Facts Every Man Should Know
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Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...
Smoking Cessation's Effects on Male Hormonal Levels
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This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis
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From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...
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