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How Compounding Pharmacies Are Challenging Big Pharma on Fair Access
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13-Minute Podcast: This podcast discussion examines the burgeoning role of compounding pharmacies, particularly in the context of GLP-1 medications, and how they are challenging the established dominance of Big Pharma. Driven by soaring drug...
Testosterone and Atrial Fibrillation
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11:25-12:50 * It is likely a U shape therapeutic curve with the lowest incidence of occuring at men with mid-range values of concentrations (350-550 ng/dL) Analysis of the Graph The graph shows a U-shaped relationship between testosterone...
Why Use hCG With TRT?- A Clinical Review
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Using hCG in Men on Testosterone Replacement Therapy (TRT) – A Clinical Review Introduction Exogenous testosterone replacement therapy (TRT) can profoundly suppress the hypothalamic-pituitary-gonadal (HPG) axis through negative feedback. By...
Deca Gains. What to expect
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Doc just prescribed me 100mg weekly of Deca for joint pain and a bad shoulder. my current protocol is Test Cyp 180mg weekly (pin eod). I am a seasoned lifter. 38 years old. about 12% bf. Pull 500 pound deadlifts for reps. Since starting TRT...

Zimislecel: Stem Cell–Derived, Fully Differentiated Islets Cured Type 1 Diabetes?

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Type I Diabetes Mellitus is a terrible disease causing premature death and morbidity. Micro and macrovascular damage are the main contributing factors to injury. This video reports on an article published in the NEJM. The treatment seems to work...
Testosterone Replacement Therapy (TRT) Facts Every Man Should Know
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Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...
Smoking Cessation's Effects on Male Hormonal Levels
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This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
Pregnenolone in Men: Help determining proper dosage and frequency
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Wondering what pregnenolone dose and frequency works best for optimizing your hormone balance on TRT? Pregnenolone, the "mother hormone" that serves as a precursor to numerous steroid hormones, requires careful dosing consideration due to its 3-4...
WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT
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Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert...

Best Sleep Supplements

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Please share which sleep supplements work best for you.
Stanford Rheumatologist Reveals Surprising Causes of Joint Pain
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Dr. Tamiko Katsumoto is a Stanford rheumatologist specializing in immunology and inflammation. She is both physician and scientist who gets over-the-top raves from her patients. The Protective Power of Food Against Joint Pain An Interview with...

Anyone taking PCSK9 inhibitors (i.e. Repatha)?

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I have a scrip for Repatha but haven't yet started. Covered by insurance so cost not an issue. Was concerned that LDL would go too low and cause issues. Also, side effects. Read that it can cause hyperglycemia (diabetes). Any input would be...

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