Health & Wellness

Oxandrolone (Anavar) : The Most Studied Oral Anabolic Agent in Wasting and Catabolic Conditions

May 20

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Oxandrolone is a man-made anabolic androgenic agent that has been studied by doctors for more than 30 years, mostly because it might help treat catabolic disorders and chronic wasting conditions like alcoholic hepatitis, severe burn injuries...

Anabolic Agents Chronic Illnesses General Health Health & Wellness Hormones Men's Health Muscle Gain Products Women's Health

The TRT Guide from ExcelMale.com

May 17

Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...

Blood Tests Erectile Dysfunction Estradiol estrogen in men Fatigue Fertility Health & Wellness Hormones How to Guides Men's Health Muscle Gain Sex drive Testicular Atrophy Testosterone Testosterone side effects TRT TRT blood tests TRT Doctors

What Every Man Needs to Know | Testosterone 101

May 17

Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...

Blood Tests Clomid (Clomiphene & Enclomiphene) Erectile Dysfunction estrogen in men Fatigue Fertility HCG Health & Wellness Heart Health Men's Health Testicular Atrophy Testosterone TRT TRT blood tests TRT Doctors

GLP-1 Medications (Semaglutide, etc.) Decrease Sex Drive

May 07

Study at a Glance Title: “Assessing the Impact of GLP-1 Receptor Agonists on Sexual Desire: A Qualitative Review” Authors: H. Quaile & R. Horwitz Journal: Journal of Sexual Medicine — published 1 April 2025 Why This Matters Glucagon-like...

Health & Wellness Men's Health Sex drive Weight Loss Women's Health

The FDA Was WRONG About Testosterone? Major Label Update Explained

May 07

In this episode, Dr. Morgentaler and Dr. Brandon talk about the FDA finally reversing its stance on testosterone risks, what that means for heart health, and why it’s a big win for science—and for patients. Chapters 00:07 – FDA's New Stance...

Health & Wellness Men's Health Testosterone Testosterone side effects TRT TRT Doctors

How Your Vitamin D Level Can Boost the Heart Health Benefits of Testosterone Therapy for Men: New Study

Apr 30

Vitamin D Status Shapes the Cardiometabolic Pay-Off of Testosterone Therapy in Late-Onset Hypogonadism Abstract Late-onset hypogonadism (LOH) is common in aging males and is frequently accompanied by features that drive cardiovascular and...

Blood Tests Health & Wellness Heart Health Men's Health Supplements TRT

Ankle swelling after starting testosterone injections

Apr 28

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I got this question from a friend of mine today who started testosterone replacement 3 weeks ago (injections of 100 mg per week): "I've been gaining a lot of weight. Does this mean my estradiol is high? I don't have any nipple soreness or severe...

Health & Wellness Heart Health Men's Health Testosterone side effects Water Retention and BP

Changes in Blood Cells May Explain Why Some Older Men Had Cardiovascular Issues Using Androgel in the TRAVERSE Trial

Apr 25

Background: Please read this previous article: https://www.excelmale.com/threads/heart-palpitations-and-afib-in-older-men-on-testosterone-signals-from-traverse.28247/ New Data...

Blood Tests Health & Wellness Heart Health Men's Health Testosterone Testosterone side effects TRT TRT blood tests

Empower Pharmacy CEO Shaun Noorian Challenges Big Pharma Over GLP-1 Drug Access and Pricing

Apr 24

Everyone is talking about GLP-1s. As these so-called "miracle drugs" for weight loss exploded in popularity, shortages quickly followed. That’s when compounding pharmacies stepped in, offering lower-cost, customizable versions of these...

Diabetes Fat Loss General Health Health & Wellness Men's Health Products Weight Loss Women's Health

What Every Man Should Know About Prostatitis

Apr 22

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What factors can falsely elevate your PSA level? There are other factors that can affect the PSA level besides prostate cancer. The following conditions can lead to increased PSA levels: Increasing age Benign prostate hyperplasia (BPH), a...

Chronic Illnesses Health & Wellness Men's Health Prostate

The Gut Microbiome and Testosterone: An Intriguing Connection

Apr 18

Introduction to the Gut Microbiome The human gut microbiome—an intricate community of trillions of bacteria and other microorganisms—has become one of the most fascinating subjects in medical research. A recent systematic review sheds new light...

General Health Health & Wellness Hormones Men's Health Testosterone Women's Health

How Can I Increase My Allopregnanolone ?

Apr 16

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We know that pregnenolone and progesterone increase allopregnanolone. Do you know any other hormones that increase allopregnanolone? Strategies to Increase Allopregnanolone for Mental Health Support Introduction: Allopregnanolone, Mood, and...

Health & Wellness Hormones Men's Health Mental Health

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038