Updated Labs - Help Please

This is a temporary fix!

Last thing you want here is to get caught up on the donating merry go round.

Many end up donating too frequently only to end up crashing their ferritin which can open up another can of worms.

You need to get to the root cause here which for the majority is running too high a trough/steady-state FT but in your case judging by all of your previous labs you never had a high-end/high FT (20-25 ng/dL) other then back in Feb/Mar when you were hitting a TT 1115/958 ng/dL!

Even then have no idea where your RBCs, hemoglobin and hematocrit sat when you were running a high-end/high TT which was only for a few months.

When first starting TTh hematocrit needs to be checked at 3 and 6 months then 12 months in as the biggest increase will be seen within the first 3-6 months.

Need to give it 6 months on said protocol (dose of T/injection frequency) to see where it truly ends up!

Where did your RBCs and H/H sit at baseline (pre-TTh)?

As of now on your current protocol you are hitting 53%!




03/17/2025:

Testosterone: 1115 ng/dL (range 300 - 1080 ng/dL)
SHBG: 39 (range 17-56 nmol/L)
Testosterone Free-Calc: 252.0 pg/mL (range 47.0 - 244 pg/mL)
*these labs were done post injection around 1:00 PM and were not trough labs.





Threw in the same SHBG 39 nmol/L as it is highly doubtful it was much higher.

02/17/2025:

Estradiol: 33.7 pg/mL (range 11.8 - 39.9)
Testosterone: 958 ng/dL (range 280 -1100)
SHBG: *not measured*
Testosterone Free-Calc: *not measured*


Hey sir, here are my results from 12/28/2024 about 2 weeks after initiating the 16mg/daily + 500iu 3x per week protocol:

1755739737228.webp

1755739759833.webp


1755739647826.webp


Here they are from 04/07/2025:

1755739872221.webp

1755739902878.webp



And then from 5/14:

Total T: 643ng/DL
SHBG: 28.6 nmol/L
Albumin: 4.5 g/dL
Calc Free Testesterone: 147 pg/mL
Estradiol 20.0 pg/mL
Ferritin 67.4 ng/mL
Hematocrit 48.8% (ref. range 39.5-49.5%)
RBCs: 5.41 (ref. range 4.40 - 5.80)


So an increase from 44.5 to 5.79 on the most recent labs for RBCs, and a corresponding increase in HCT.

I donated blood this afternoon after work. I am not sure what else I should do besides retesting in 4 weeks to see where things stand? Very open to suggestions.
 

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Hey sir, here are my results from 12/28/2024 about 2 weeks after initiating the 16mg/daily + 500iu 3x per week protocol:

View attachment 52628
View attachment 52629

View attachment 52627


Here they are from : 04/07/2025
View attachment 52630
View attachment 52631


And then from 5/14:

Total T: 643ng/DL
SHBG: 28.6 nmol/L
Albumin: 4.5 g/dL
Calc Free Testesterone: 147 pg/mL
Estradiol 20.0 pg/mL
Ferritin 67.4 ng/mL
Hematocrit 48.8% (ref. range 39.5-49.5%)
RBCs: 5.41 (ref. range 4.40 - 5.80)


So an increase from 44.5 to 5.79 on the most recent labs for RBCs, and a corresponding increase in HCT.

I donated blood this afternoon after work. I am not sure what else I should do besides retesting in 4 weeks to see where things stand? Very open to suggestions.

12/28/2024

Your baseline hematocrit would have been close to 44% as you were hitting 44.5% 2 weeks after starting exogenous T which means nothing as the biggest increase will been seen 3-6 months after starting therapy and there can still be a further increase up to a year.


04/07/2025

Just over 3 months on therapy your hematocrit went from 44-49.5%.


5/14/2025

4.5 months in it was sitting at 48.8%


5/29/2025

5 months in your hematocrit is a whopping 53.1%.

Your baseline pre-TT was around 44% and 5 months in has risen drastically!


Need to get to the root cause here as again looking over all the labs you posted unfortunately using different labs as your reference ranges are all over the place you only spent a few months with a high-end/high trough FT.

Even if you were running a high-end/high trough FT from the get-go there is no way you would see a drastic increase 44-53.1% from T-therapy.

This should have been a red flag here as your doctor seems to be out to lunch!
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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