Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene

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Jntsrgn

Member
Just want to add my protocol.... I take 20mg of Test Cyp on MWF (down from 60mg) along with 250 IU of HCG and 75 IU of HMG. My total T last draw was 1100 and Free T 244. E2 is always 60-70 without symptoms and I do not take any Anastrozole. Adding the HCG and HMG brought me from a completely absent sperm count to 15 million fully functional swimmers on my last analysis. I was able to become fertile without stopping TRT.
 
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Mastodont

Active Member
Is there anyone who has tried infrequent large doses of gonadorelin? Curious if gonadorelin is enough to prevent testicular shrinkage if taken daily or even eod-e3d.
In my country it's only available for cows, dont know if i could identify as one and get it prescribed, but it is 50micrograms per ml, larger doses might be problematic subq.
 

Cataceous

Super Moderator
Is there anyone who has tried infrequent large doses of gonadorelin? Curious if gonadorelin is enough to prevent testicular shrinkage if taken daily or even eod-e3d.
In my country it's only available for cows, dont know if i could identify as one and get it prescribed, but it is 50micrograms per ml, larger doses might be problematic subq.
As mentioned later in this post on the previous page, Royal Medical Center is or was using such protocols. I haven't noticed patients of theirs making comments here, but it's possible there are reports elsewhere. It would be good to know if the relatively infrequent, but robust pulses of LH and FSH are sufficient to prevent testicular atrophy. I don't recall if we nailed down the exact protocol, but I believe it was either 50 or 100 mcg taken once or twice a week.
 
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