Testosterone side effects

ExcelMale Newsletter Signup

What are the best blood pressure medications to avoid erectile dysfunction?

Jan 06

Are your blood pressure medications affecting your erections? This is one of the most common questions men ask when prescribed antihypertensive therapy—and for good reason. Many men on testosterone replacement therapy (TRT) also require blood...

Erectile Dysfunction General Health Men's Health Testosterone side effects TRT

Sex Hormone Binding Globulin (SHBG): The Complete Guide for Men on TRT

Jan 02

By Nelson Vergel | ExcelMale.com | Updated December 2025 When evaluating testosterone levels, most men focus exclusively on total testosterone—a single number that tells only part of the story. What many don't realize is that a protein called...

Blood Tests Hormones Peptides Testosterone Testosterone side effects TRT blood tests

Subcutaneous Testosterone Injections: The Complete Guide for Men on TRT

Jan 02

Are you tired of painful intramuscular injections and wondering if there's a more comfortable way to administer your testosterone replacement therapy? For decades, intramuscular (IM) injections have been the standard method for testosterone...

High Hematocrit Men's Health Testosterone Testosterone side effects TRT

Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options

Dec 29

By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier...

Men's Health Testosterone Testosterone side effects TRT

Testosterone and Your Heart: What a Major New Study Really Found

Dec 29

Summary: The TRAVERSE trial, a landmark FDA-mandated study involving over 5,200 men, has definitively concluded that testosterone replacement therapy (TRT) does not increase the risk of major cardiovascular events like heart attacks, strokes, or...

Heart Health Men's Health Muscle Gain Testosterone side effects

Clascoterone: New Hair Loss Treatment Safer than Finasteride?

Dec 18

1,176
13

Learn how clascoterone works, clinical uses for hair loss and acne, dosing basics, and safety considerations. Clascoterone 5% Topical Solution for Male Androgenetic Alopecia Overview Clascoterone 5% topical solution represents what could be the...

Hair loss Men's Health Testosterone side effects

US Federal and State Regulations on Testosterone and HCG

Dec 17

22,725
5

Testosterone is a controlled substance in the US, specifically a Schedule-III controlled substance (in all but one State), and this includes any form of testosterone including injectable, transdermal, patches, pellets, and any compound or product...

Men's Health Testosterone Testosterone side effects TRT

Key Historical Failures and Lessons Learned from Attempts to Get a Testosterone Product FDA-Approved for Women

Dec 12

FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...

Hormones HRT in Women Testosterone Testosterone side effects TRT Women's Health

HCG Use in Men on TRT or as Monotherapy: Over 200 Questions and Answers

Dec 05

22,864
25

I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...

Fertility HCG Hormones Men's Health Sex drive Testosterone Testosterone side effects TRT

Upcoming FDA Expert Panel on Testosterone Replacement Therapy for Men

Dec 02

@Nelson Vergel We need you here! https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025 Location: FDA White Oak Campus, 10903 New Hampshire Ave., Building 31, Great Room, Silver...

Men's Health Testosterone Testosterone side effects TRT

HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

Nov 15

9,332
56

What's the best HCG dosing protocol for men on TRT? Whether you're using HCG to maintain fertility, prevent testicular atrophy, or preserve intratesticular testosterone, the dosing frequency matters. Should you inject daily, every other day, or...

Fertility HCG Men's Health Sex drive Sperm count Testosterone side effects

Options for Delayed or Absent Orgasms Despite Stimulation in Men

Nov 15

Experiencing delayed orgasm or anorgasmia on TRT? Many men on testosterone therapy report difficulty reaching climax despite normal erections and libido. This frustrating issue is more common than most realize—and it's often treatable once you...

Erectile Dysfunction Estradiol estrogen in men Men's Health Sex drive Testosterone side effects TRT