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Why Some Men on TRT Experience Anxiety and Brain Fog Despite Optimal Testosterone Levels
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Understanding the Role of Neurosteroids, Upstream Hormones, and Practical Solutions Curated By Nelson Vergel | ExcelMale.com Introduction: The TRT Paradox One of the most frustrating experiences reported by men on testosterone replacement...
How to Increase Allopregnanolone, The Happiness Neurosteroid.
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DEEP DIVE: Strategies to Increase Allopregnanolone A Comprehensive Review for Mental Health Support 1. What is Allopregnanolone? Allopregnanolone (ALLO) is a neurosteroid synthesized from progesterone that acts as a potent positive allosteric...
Palmitoylethanolamide (PEA) Pain Management: A Comprehensive Review
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Palmitoylethanolamide (PEA) A Comprehensive Review of Mechanisms, Clinical Evidence, and Practical Applications January 2026 Abstract Palmitoylethanolamide (PEA) is an endogenous fatty acid amide belonging to the N-acylethanolamine family with...
Top 20 Hair Research Studies of 2025 - Minoxidil, Finasteride, Dutasteride
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The 20 Most Influential Hair Research Studies of 2025 A Comprehensive Review of the Year's Groundbreaking Findings in Hair Loss Treatment and Research Based on Dr. Donovan's Year-End Webinar | December 29, 2025 As we close out 2025, it's an...
FDA Testosterone Regulation: The Complete Guide to Label Changes, Cardiovascular Safety, and the Future of TRT Access
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FDA Testosterone Regulation: The Complete Guide to Label Changes, Cardiovascular Safety, and the Future of TRT Access Curated By Nelson Vergel | ExcelMale.com | Updated January 2026 Is testosterone replacement therapy finally being recognized...
Coronary Artery Calcium (CAC) scoring and Coronary Computed Tomographic Angiography (CCTA) in Men with Low Testosterone
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Diagnostic Assessment Strategy: Cardiovascular Risk & Systemic Health in Hypogonadal Patients 1. Strategic Framework for Cardiovascular Risk in the Hypogonadal Male In the contemporary clinical landscape, the management of the hypogonadal male...
Options for Hair Loss Beyond Propecia
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Reversing and preventing hair loss can be a primary concern for many men and women who experience hair loss or thinning. Unfortunately hair loss can affect people at any point in their life, sometimes beginning in their 20s. According to the Mayo...
What are the best blood pressure medications to avoid erectile dysfunction?
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Are your blood pressure medications affecting your erections? This is one of the most common questions men ask when prescribed antihypertensive therapy—and for good reason. Many men on testosterone replacement therapy (TRT) also require blood...
Sex Hormone Binding Globulin (SHBG): The Complete Guide for Men on TRT
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By Nelson Vergel | ExcelMale.com | Updated December 2025 When evaluating testosterone levels, most men focus exclusively on total testosterone—a single number that tells only part of the story. What many don't realize is that a protein called...
Subcutaneous Testosterone Injections: The Complete Guide for Men on TRT
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Are you tired of painful intramuscular injections and wondering if there's a more comfortable way to administer your testosterone replacement therapy? For decades, intramuscular (IM) injections have been the standard method for testosterone...
Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options
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By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier...
Testosterone and Your Heart: What a Major New Study Really Found
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Summary: The TRAVERSE trial, a landmark FDA-mandated study involving over 5,200 men, has definitively concluded that testosterone replacement therapy (TRT) does not increase the risk of major cardiovascular events like heart attacks, strokes, or...

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