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Sex hormones like estrogen and testosterone don’t just affect things like body shape or voice—they also play a role in how the immune system works. This is especially important for transgender people who take these hormones as part of their...
Download slides (from my book "Beyond Testosterone"): Estradiol in Men Slides Estradiol in Men: The Stigma In the 2014 film The Other Woman, Cameron Diaz, Leslie Mann, and Kate Upton, portray three jilted females who discover they are...
Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...
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I got this question from a friend of mine today who started testosterone replacement 3 weeks ago (injections of 100 mg per week): "I've been gaining a lot of weight. Does this mean my estradiol is high? I don't have any nipple soreness or severe...
TRT Hormone Predictor Widget
TRT Hormone Predictor
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
