Heart Health

Unmasking Risks: Prevalence of Erythrocytosis Among Men on T-Therapy Across Different Formulations

Sep 17

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* The study population included men with (i) early morning total testosterone (TT) using LCMS, (ii) free T (FT) measured using equilibrium dialysis, and (iii) who were started on TTH. * Men using intramuscular or topical testosterone face a...

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How to Lower High Hematocrit Caused by Testosterone Replacement Therapy (TRT)

Jul 23

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High Hematocrit Caused by Testosterone Replacement Therapy By Nelson Vergel, B.S.Ch.E., M.B.A. High hematocrit occurs when there is an excessive production of red blood cells. High hematocrit can cause the blood to become very viscous or...

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FDA Expert Panel on Menopause and HRT Recommends Removing Black Box Labels

Jul 19

This was a very important meeting with top experts that are trying to change guidelines. This FDA panel recently recommended removing the warning (“black box”) labels on menopausal HRT, citing potential benefits like reduced heart attack and bone...

Heart Health Hormones HRT in Women Women's Health

Managing Erectile Dysfunction & Heart Health

Jul 18

Dr. Dapo lluyomade * I think erectile dysfunction, we should really begin to think of erectile dysfunction as subclinical atherosclerosis until proven otherwise Is your patient’s sexual dysfunction an early indicator of serious...

Erectile Dysfunction Heart Health Men's Health

Can Certain Blood Pressure Medications Decrease Hematocrit?

Jul 17

ARBs, or Angiotensin II Receptor Blockers, are a class of medications primarily used to treat high blood pressure (hypertension). They also play a role in managing heart failure and protecting kidney function, particularly in patients with...

Heart Health High Hematocrit Men's Health Testosterone side effects TRT

New Zealand does not let me give blood to decrease high hematocrit on TRT

Jul 12

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Hi Guys Blood lab turned me away for having Haemoglobin of 198. Apparently the limit is 185(Here in New Zealand) I am currently on 80mg(split twice a week 40+40)of test cyp deep IM. Have been on this for 4 months and going well. Can't do and...

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Iron Supplementation Protocol to Raise Ferritin FAST While on TRT: The Vorck Protocol

Jul 12

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The Vorck Protocol Summary Background: The protocol was developed by a TRT user since 2001 who had difficulty recovering ferritin levels after blood donations. After conducting personal research and consulting with a hematologist in May 2021, he...

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Testosterone and Atrial Fibrillation

Jul 04

11:25-12:50 * It is likely a U shape therapeutic curve with the lowest incidence of occuring at men with mid-range values of concentrations (350-550 ng/dL) Testosterone Therapy and Cardiovascular Risk: Insights from an Interventional...

Health & Wellness Heart Health Men's Health Testosterone side effects TRT

Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

Jun 22

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From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...

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WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT

Jun 17

Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert...

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Anyone taking PCSK9 inhibitors (i.e. Repatha)?

Jun 09

I have a scrip for Repatha but haven't yet started. Covered by insurance so cost not an issue. Was concerned that LDL would go too low and cause issues. Also, side effects. Read that it can cause hyperglycemia (diabetes). Any input would be...

Chronic Illnesses Health & Wellness Heart Health

What Every Man Needs to Know | Testosterone 101

May 17

Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038