Heart Health

Anyone taking PCSK9 inhibitors (i.e. Repatha)?

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I have a scrip for Repatha but haven't yet started. Covered by insurance so cost not an issue. Was concerned that LDL would go too low and cause issues. Also, side effects. Read that it can cause hyperglycemia (diabetes). Any input would be...
What Every Man Needs to Know | Testosterone 101
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Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...
New Drug Rusfertide: Managing Polycythemia Vera to Reduce Risks and Improve Lives
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Polycythemia vera is a classic myeloproliferative neoplasm and a chronic type of leukemia, which often leads to overproduction of various blood cells. Summary: Managing Polycythemia Vera to Reduce Risks and Improve Lives Polycythemia vera (PV)...
How Your Vitamin D Level Can Boost the Heart Health Benefits of Testosterone Therapy for Men: New Study
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Vitamin D Status Shapes the Cardiometabolic Pay-Off of Testosterone Therapy in Late-Onset Hypogonadism Abstract Late-onset hypogonadism (LOH) is common in aging males and is frequently accompanied by features that drive cardiovascular and...
Ankle swelling after starting testosterone injections
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I got this question from a friend of mine today who started testosterone replacement 3 weeks ago (injections of 100 mg per week): "I've been gaining a lot of weight. Does this mean my estradiol is high? I don't have any nipple soreness or severe...
Changes in Blood Cells May Explain Why Some Older Men Had Cardiovascular Issues Using Androgel in the TRAVERSE Trial
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Background: Please read this previous article: https://www.excelmale.com/threads/heart-palpitations-and-afib-in-older-men-on-testosterone-signals-from-traverse.28247/ New Data...

Best Medications to improve Ejection Fraction in Testosterone Users?

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It turns out I had crazy high blood pressure (170/100), likely for months, too much caffeine, stress and I'm 125kg/275 pounds / 192cm/6'4, 44 years old. Last week a cardiologist put me on Dipperam 5+160 (5mg Amlodipine + 160mg Valsartan), using...
Heart Palpitations and AFIB in Older Men on Testosterone: Signals from TRAVERSE
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Heart palpitations and AFIB (Atrial Fibrillation) risk in older men using testosterone is examined in the video below. Highlights [⚠️] Testosterone use in older men and its link to heart palpitations and AFIB. [] Research findings suggest a...
Left Ventricle Hypertrophy and Nandrolone ( Decadurabolin )
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Dear Nelson Vergel and forum members, I am a long time reader, first time poster, In fact I registered just to post these questions. While I have addressed this to Nelson specifically I would be very grateful for any evidence-based input from...
Fluoroless Pulsed Field Ablation of Atrial Fibrillation
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Mansour Razminia, MD, a cardiac electrophysiologist at Northwestern Medicine, discusses the innovative technique of fluoroless pulsed field ablation (PFA) for treating atrial fibrillation. He explains how this ultra-rapid electrical field safely...
Rises in Hematocrit is Associated with An Increased Risk of Cardiac Events in Men Starting Testosterone Therapy
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ABSTRACT Objective Elevated hematocrit (Hct) can result in increased risk of major adverse cardiac events(MACE) in men receiving testosterone therapy (TTh). However, the impact of the magnitude of the change in Hct from baseline after starting...

Is it safe for men with history of pulmonary embolism who are taking blood thinners to start testosterone ?

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There are no published studies conducted on men with a history of pulmonary embolism (PE) who are taking blood thinners and want to use testosterone replacement therapy (TRT). However, they do provide a broad overview of the relationship between...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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