Blood Tests

Testosterone/Estradiol Ratio: The Hidden Key to Low Libido in Men with Sexual Dysfunction?

Jul 07

Poster 149: Testosterone/Estradiol Ratio and Low Libido in Men with Sexual Dysfunction Title TESTOSTERONE: ESTRADIOL RATIO A STEP FORWARD TOWARDS THE UNDERSTANDING OF LOW LIBIDO IN MEN WITH SEXUAL DYSFUNCTION Authors Rodrigo Freddi, Rubens...

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Estrogen-It's what makes a real man

Jul 05

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Study: Low estrogen can cause problems for men Study: Low estrogen can cause problems for men (2013) Dr. Joel Finkelstein, an endocrinologist at Harvard Medical School and the lead author of a new study, talks about the effects of declining...

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Metabolic benefits afforded by estradiol and testosterone in both sexes

Jul 05

As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones...

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Why Use hCG With TRT?- A Clinical Review

Jul 02

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Using hCG in Men on Testosterone Replacement Therapy (TRT) – A Clinical Review Introduction Exogenous testosterone replacement therapy (TRT) can profoundly suppress the hypothalamic-pituitary-gonadal (HPG) axis through negative feedback. By...

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Smoking Cessation's Effects on Male Hormonal Levels

Jun 22

This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...

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Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

Jun 22

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From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...

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Pregnenolone in Men: Help determining proper dosage and frequency

Jun 21

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Hi all, I've been experimenting with pregnenolone for over a year now, with varied success. I seem to get benefits at 100mg (such as higher libido, more pronounced nighttime erections and better sleep); however, I don't get these results...

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WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT

Jun 17

Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert...

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Testosterone Therapy Induced High Hematocrit- Can Therapeutic Phlebotomy Be a Double-Edged Sword?

Jun 14

https://ec.bioscientifica.com/view/journals/ec/aop/ec-24-0283/ec-24-0283.xml Therapeutic Phlebotomy: A Double-Edged Sword? Current Guidelines: "Several endocrine organizations mention therapeutic phlebotomy as a means of treating TTh–induced...

Blood Tests High Hematocrit Men's Health Testosterone side effects TRT

High Estradiol in Men on TRT: What to Do

Jun 11

Briefing Document: Estradiol in Men on TRT Source: Excerpts from "High Estradiol in Men on TRT: What to Do" by Nelson Viegel (excelmale.com) 1. The Role and Importance of Estradiol in Men Core Idea: Estradiol, often misconstrued as a solely...

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Diagrams: Accurate Androgen and Estrogen Measurement in Human Serum and Plasma

Jun 06

* Probably the most challenging forms to quantify, due to their relatively low concentrations are the so called free forms. The free forms of all the hormones (shown in Figs. 1–3) are the hormones not bound to proteins, or conjugated to other...

Blood Tests Hormones TRT blood tests

Testosterone blood level is correlated with immune cell abundance in transgender young people on gender affirming hormones

Jun 03

Sex hormones like estrogen and testosterone don’t just affect things like body shape or voice—they also play a role in how the immune system works. This is especially important for transgender people who take these hormones as part of their...

Blood Tests Health & Wellness Hormones Testosterone Testosterone side effects TRT

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038