Blood Tests

Estradiol: The "Other" Male Hormone
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Download slides (from my book "Beyond Testosterone"): Estradiol in Men Slides Estradiol in Men: The Stigma In the 2014 film The Other Woman, Cameron Diaz, Leslie Mann, and Kate Upton, portray three jilted females who discover they are...
Managing the Testosterone-to-Estradiol Ratio in Men on TRT
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Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...
The TRT Guide from ExcelMale.com
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Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...
What Every Man Needs to Know | Testosterone 101
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Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...
Regular testosterone test overestimates hypogonadism in men compared to the LC-MS/MS assay
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* IA compared to LC-MS/MS in hypogonadal men overestimates significantly both the prevalence of biochemical Hy and TRT compensation both for TT and cfT. These results highlight the role of LC-MS/MS and SHBG assessments in every day clinical...
How Your Vitamin D Level Can Boost the Heart Health Benefits of Testosterone Therapy for Men: New Study
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Vitamin D Status Shapes the Cardiometabolic Pay-Off of Testosterone Therapy in Late-Onset Hypogonadism Abstract Late-onset hypogonadism (LOH) is common in aging males and is frequently accompanied by features that drive cardiovascular and...
Changes in Blood Cells May Explain Why Some Older Men Had Cardiovascular Issues Using Androgel in the TRAVERSE Trial
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Background: Please read this previous article: https://www.excelmale.com/threads/heart-palpitations-and-afib-in-older-men-on-testosterone-signals-from-traverse.28247/ New Data...
How Many Men Have False-Positive PSA Tests that Lead to Unnecessary Biopsies?
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PSA Screening, Prostate Biopsies, and Prostatitis: Prevalence and Outcomes Frequency of PSA-Triggered Biopsies (U.S. and Global) Prostate-specific antigen (PSA) screening became widespread in the 1990s, resulting in a high volume of prostate...
Testosterone Assays
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Testosterone Assays (2022) Brendan King, MD, Caleb Natale, MD, Wayne J.G. Hellstrom, MD The accurate detection and quantification of serum testosterone levels are necessary for the diagnosis of hypogonadism in men, evaluation of endocrine...
Controversies with Testosterone Replacement Therapy: Lecture by Dr Khera
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As usual Nelson's Excel is where it's at! Mohit Khera, MD, MBA, MPH, Professor of Urology, F Brantley Scott Chair in Urology, Medical Director of the Laboratory for Andrology Research, Medical Director for the Scott Department of Urology...

Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

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All, I react very badly to injectable T (56 hematocrit @ 100 mg split 3x per week SubQ). My ferritin suffers greatly here and sits in the 20's to low 30's. I want it to be above 70. Testosterone have given me a severe case of periodic limb...
Iron Supplements: How to get the most benefits without feeling sick
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Have you tested your iron levels lately? Are you currently taking iron? Are you taking it every day? (spoiler alert: you don't want to take iron every day!) Iron may be a standard, almost boring supplement to think about, but having adequate...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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