Excel Male TRT Forum

The Evolution of Testosterone Products in the U.S. (1935-2025)

Jun 27

Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early...

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Deca Gains. What to expect

Jun 26

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Doc just prescribed me 100mg weekly of Deca for joint pain and a bad shoulder. my current protocol is Test Cyp 180mg weekly (pin eod). I am a seasoned lifter. 38 years old. about 12% bf. Pull 500 pound deadlifts for reps. Since starting TRT...

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Shifting the Testosterone Treatment Paradigm with Oral Testosterone (Kyzatrex)

Jun 26

Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape...

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Zimislecel: Stem Cell–Derived, Fully Differentiated Islets Cured Type 1 Diabetes?

Jun 24

Type I Diabetes Mellitus is a terrible disease causing premature death and morbidity. Micro and macrovascular damage are the main contributing factors to injury. This video reports on an article published in the NEJM. The treatment seems to work...

Chronic Illnesses Health & Wellness

Postorgasmic Illness Syndrome: An Update

Jun 24

Briefing Document: Postorgasmic Illness Syndrome (POIS) Source: (Zizzo, Sávio, Ramasamy, Lima, 2022) I. Executive Summary Postorgasmic Illness Syndrome (POIS) is a rare and poorly understood condition primarily affecting men, characterized by a...

Men's Health Sex drive

Testosterone Replacement Therapy (TRT) Facts Every Man Should Know

Jun 23

Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...

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Smoking Cessation's Effects on Male Hormonal Levels

Jun 22

This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...

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Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

Jun 22

From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...

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Pregnenolone in Men: Help determining proper dosage and frequency

Jun 21

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Hi all, I've been experimenting with pregnenolone for over a year now, with varied success. I seem to get benefits at 100mg (such as higher libido, more pronounced nighttime erections and better sleep); however, I don't get these results...

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The hormonal regulation of men’s sexual desire, arousal, and penile erection

Jun 21

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Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...

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Lipo-C - Who's using / what doses?

Jun 20

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Hey Folks, I'm curious to see who is using Lipo-C, what your dose/injection schedule is, and what your results (subjective or not) are so far. I recently started with Defy. Dr. Saya had no problem adding Lipo-C to my regimen. (I'm dying for...

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Anastrozole - Enduring Side Effects 5 Years Later

Jun 19

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Hello all, I’m 28yo male in the US. When I was in my early 20s, I had a residual puffy nipple from puberty. I was very self conscious about this, being pretty deep in weight lifting, and my primary care physician prescribed an anti-estrogen...

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