How to transition from injections to cream?

Protonus

New Member
What is the correct protocol to transition from cypionate injections to cream? I am taking 60mg e3d of cyp currently and would like to switch to 50mg of cream to the scrotum daily. I am due for my next shot tomorrow. Should I start with 25mg per day for a week and then up to 50 or is there a better way?
 
The change is going to possibly be bumpy for you no matter how you approach it. I would prefer to have a spike (as you call it) than stop cold turkey for 2-3 (or 4) weeks and then start up with the cream.
 
I think your plan to stop injections and ramp up the cream over two to three weeks is a good one. You'll still feel the transition, but there's no need to make it worse with bigger hormonal fluctuations.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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