How to calc Cyp to scrotal cream doses?

Rentner2022

New Member
I (54M) am currently taking 130 Test Cyp a week but want to try scrotal cream to see if it is better at improving libido symptoms. Currently 130 TC/wk (split 3x) puts me at about the right overall level (trough TT at 1000, free T at 25, E2 sensitive at 34). But I don't want to switch entirely, I want to move to a split protocol.

So here's what I was thinking- if one click is .25 ml and it's a 50 mg/ml cream, then that's 12.5 Test per click. At a 50% absorption rate that 6 mg Test absorbed per click. 130 mg/wk injected is 18.5 mg/day of TC. I think TC is about 70% Test so that's 13 mg Test/day. So if I wanted to start with a split protocol adding one click a day of cream that means I can cut my TC injections by half (to say maybe 70 mg/wk)?

Do I have that math right? Has anyone done anything similar?
 
If you have an idea of how you absorb you could get a better calculation. But you don't know that yet so you're taking a shot in the dark.
 
I would use the half of a normal shoulder dose and look from there. Since your bloods will stabilize in days you can dial it in pretty fast.

there are two studies about transscrotal application:


scrotum appl. is 5-8 times stronger than normal skin sites
 
I (54M) am currently taking 130 Test Cyp a week but want to try scrotal cream to see if it is better at improving libido symptoms. Currently 130 TC/wk (split 3x) puts me at about the right overall level (trough TT at 1000, free T at 25, E2 sensitive at 34). But I don't want to switch entirely, I want to move to a split protocol.

So here's what I was thinking- if one click is .25 ml and it's a 50 mg/ml cream, then that's 12.5 Test per click. At a 50% absorption rate that 6 mg Test absorbed per click. 130 mg/wk injected is 18.5 mg/day of TC. I think TC is about 70% Test so that's 13 mg Test/day. So if I wanted to start with a split protocol adding one click a day of cream that means I can cut my TC injections by half (to say maybe 70 mg/wk)?

Do I have that math right? Has anyone done anything similar?

If you want to replicate a trough TT of 1000 with a 20% cream, try 2 clicks AM and 2 clicks PM and see where that get you 12h after application.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
8
Guests online
139
Total visitors
147

Latest posts

Back
Top