Acne on TRT - A low dose Accutane?

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madman

Super Moderator
Does low progesterone cause acne?

Again it is plain as day.....your trough FT level is absurdly high!

You are running a trough TT 1200 ng/dL with an SHBG of only 30 nmol/L.

Yet you keep on trying to convince yourself it is something else!

Unf**king real to say the least.


From 2 of your previous threads:


I feel pretty good, but Ive been breaking out like crazy since bumping up my dose. any suggestions?



I know many have experience with Accutane, and claim that they cleared their Acne up permanently, But does anyone have experience with retinol, which is essentially topical Accutane?

since upping my dose, I’ve experienced a bit of acne. But I don’t want to take Accutane due to the long-term side effects. I’d rather exhaust other options first, so I’ve been thinking about taking retinol.

For those who have taken it, what was your experience like? Does it permanently shrink the sebum glands like Accutane does?
 
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madman

Super Moderator
Does low progesterone cause acne
post# 5

post# 26

post #30


William Llewellyn’s book:
ANABOLICS



"As mentioned, testosterone also elicits androgenic activity, which occurs by its activating receptors in what are considered to be androgen responsive tissues (often through prior conversion to dihydrotestosterone. See DHT Conversion). This includes the sebaceous glands, which are responsible for the secretion of oils in the skin. As the androgen level rises, so does the release of oils. As oil output increases, so does the chance for pores becoming clogged (we can see why acne is such a common side effect of steroid use). The production of body and facial hair is also linked to androgen receptor activation in skin and scalp tissues. This becomes most noticeable as boys mature into puberty, a period when testosterone levels rise rapidly, and androgen activity begins to stimulate the growth of hair on the body and face. Some time later in life, and with the contribution of a genetic predisposition, androgen activity in the scalp may also help to initiate male-pattern hair loss. It is a misconception that dihydrotestosterone is an isolated culprit in the promotion of hair loss, however; as in actuality it is the general activation of the androgen receptor that is to blame (see DHT Conversion). The functioning of sex glands and libido are also tied to the activity of androgens, as are numerous other regions of the central nervous/neuromuscular system"


DHT and Androgenic Side Effects

"In some regards, this local potentiation of testosterone's activity may be unwelcome, as higher androgenic activity in certain tissues may produce a number of undesirable side effects. Acne, for example, is often triggered by dihydrotestosterone activity in the sebaceous glands, and the local formation of dihydrotestosterone in the scalp is typically blamed for triggering male pattern hair loss. You should know that it is a terrible misconception among bodybuilders that dihydrotestosterone is an isolated culprit when it comes to these side effects. All anabolic/androgenic steroids exert their activities, both anabolic and androgenic, through the same cellular androgen receptor"

"Dihydrotestosterone is no different than any other steroid except that it is a more potent activator of this receptor than most, and can be formed locally in certain androgen-sensitive tissues. All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and DHT has no known unique ability in this regard"


The main point to keep in mind regarding acne or hair loss (genetically prone individuals).....is that DHT is not the sole contributor and it is the general activation of the AR that is responsible.

As Nelson stated any AAS other than testosterone can result in acne in genetically prone individuals.
 

Arcane

Active Member
Again it is plain as day.....your trough FT level is absurdly high!

You are running a trough TT 1200 ng/dL with an SHBG of only 30 nmol/L.

Yet you keep on trying to convince yourself it is something else!

Unf**king real to say the least.


From 2 of your previous threads:


I feel pretty good, but Ive been breaking out like crazy since bumping up my dose. any suggestions?



I know many have experience with Accutane, and claim that they cleared their Acne up permanently, But does anyone have experience with retinol, which is essentially topical Accutane?

since upping my dose, I’ve experienced a bit of acne. But I don’t want to take Accutane due to the long-term side effects. I’d rather exhaust other options first, so I’ve been thinking about taking retinol.

For those who have taken it, what was your experience like? Does it permanently shrink the sebum glands like Accutane does?
I already lowered my dose. I didnt ask about free test. I asked about progesterone to a different poster. Seriously, relax.
 

madman

Super Moderator
Does low progesterone cause acne

Hate to burst your bubble here and although far from common even nandrolone in high enough doses can cause acne!

*All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and DHT has no known unique ability in this regard"







*Acne, for example, is often triggered by dihydrotestosterone activity in the sebaceous glands, and the local formation of dihydrotestosterone in the scalp is typically blamed for triggering male pattern hair loss. You should know that it is a terrible misconception among bodybuilders that dihydrotestosterone is an isolated culprit when it comes to these side effects.
All anabolic/androgenic steroids exert their activities, both anabolic and androgenic, through the same cellular androgen receptor"

*"Dihydrotestosterone is no different than any other steroid except that it is a more potent activator of this receptor than most, and can be formed locally in certain androgen-sensitive tissues. All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and DHT has no known unique ability in this regard"
 

madman

Super Moderator
I already lowered my dose. I didnt ask about free test. I asked about progesterone to a different poster. Seriously, relax.
Unfortunately, everything is going over your head.

Could care less where one runs their FT levels if blood markers remain healthy and they are not battling any sides.

You are the one struggling with the acne.....not me.

Give it time than as even when lowering T dose hormones will be in flux during the weeks leading up until blood levels stabilize (4-6 weeks).

The acne will take time to reside.
 

madman

Super Moderator
Hammer this in your head!

*All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and DHT has no known unique ability in this regard"
 

Arcane

Active Member
Hammer this in your head!

*All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and DHT has no known unique ability in this regard"
Unfortunately, everything is going over your head.

Could care less where one runs their FT levels if blood markers remain healthy and they are not battling any sides.

You are the one struggling with the acne.....not me.

Give it time than as even when lowering T dose hormones will be in flux during the weeks leading up until blood levels stabilize (4-6 weeks).

The acne will take time to reside.
Hey bud. This isnt my thread, I already took your advice. @Gianluca said to check is progesterone so I asked him if that could be a cause of acne as well. You've already told me about Free Test tons of times. I Already "heard" you the first hundred times. hammer that in your head.

Can I make a post on these forums without you having a mental breakdown every time?
 

madman

Super Moderator
Hey bud. I already took your advice. Some guy said to check is progesterone so I asked him if that could be a cause of acne as well. You've already told me about Free Test tons of times. I Already "heard" you the first hundred times. hammer that in your head

Like I said plain and simple you're running too high trough FT level!

Yet you keep playing stupid.
 

Arcane

Active Member
Like I said plain and simple you're running too high trough FT level!

Yet you keep playing stupid.
like i said a million times. I already heard you and took your advice. My question to gianluca has nothing to do with that. Please relax
 

madman

Super Moderator
Update!

I now use 125mg Test E E6D.
That still caused acne problems so for now I use below protocol to have clear skin:

20mg Accutane EOD.

3x2g L-carnitine ED.
3x500mg Vitamine B5 ED.

I am gonna run out of accutane eventually and hope the B5/L-carnitine mix will be enough to keep the acne away.

Ps. and i wash with Emu oil soap everyday.

Regardless of lowering your dose from an absurd 250 mg t/week--->125 mg every 6 days you need to know where your trough FT level truly sits on the current protocol.

One can easily have high FT using such dose especially if you have lowish/low SHBG and even then many with higher SHBG could easily achieve a healthy let alone high FT on such dose.

SHBG will have a significant impact on TT/FT let alone can dictate what injection frequency may suit you best.

The only way to know where your FT truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration.

Regarding the use of Accutane although it can be an extremely effective medication it can cause side effects.

Personally, I would not use it.

Come to your own conclusions!

 

S1W

Well-Known Member
Looks like OP has already made his decision, however I figured I’d chime in with my general recommendation to avoid Accutane.

I strongly suspect Accutane use is one of the main reasons I’m currently on TRT.
 

Gianluca

Well-Known Member
Hey bud. This isnt my thread, I already took your advice. @Gianluca said to check is progesterone so I asked him if that could be a cause of acne as well. You've already told me about Free Test tons of times. I Already "heard" you the first hundred times. hammer that in your head.

Can I make a post on these forums without you having a mental breakdown every time?
Like Gman86 explained earlier, Progesterone counteracts E2 and DHT, peraphs a better word to use is balance, after all HRT is not only TT FT, all major hormones needs to be in balance. When I increased my progesterone level, I remember improving my body acne, and E2 symptoms. To note, my progesterone was rack bottom

I’m a low SHBG guy, when I also optimized my Thyroid I saw an improvement in body acne, most likely for less free DHT floating around
 

Gman86

Member
Like Gman86 explained earlier, Progesterone counteracts E2 and DHT, peraphs a better word to use is balance, after all HRT is not only TT FT, all major hormones needs to be in balance. When I increased my progesterone level, I remember improving my body acne, and E2 symptoms. To note, my progesterone was rack bottom

I’m a low SHBG guy, when I also optimized my Thyroid I saw an improvement in body acne, most likely for less free DHT floating around
Are u still taking progesterone?

How did optimizing ur thyroid decrease DHT? By increasing ur SHBG and binding to more of the DHT in ur system?
 

Gianluca

Well-Known Member
Are u still taking progesterone?

How did optimizing ur thyroid decrease DHT? By increasing ur SHBG and binding to more of the DHT in ur system?
I do, but pertaining the thread, my Progesterone level was increased with pregnenolone Capsule. I didn't say Optimizing Thyroid lowered DHT, but I had an improvement with my body acne. I assumed because my SHBG increased back then, leaving less Free Sex Hormones available,
 

gerardo

Member
I do, but pertaining the thread, my Progesterone level was increased with pregnenolone Capsule. I didn't say Optimizing Thyroid lowered DHT, but I had an improvement with my body acne. I assumed because my SHBG increased back then, leaving less Free Sex Hormones available,
Is a 50 mg capsule of progesterone enough to increase progesterone to 0.4? Thank
 
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