Body & Face Acne 8 Weeks On TRT

binkskii

New Member
Hey everyone,

I have been on 100mg of Testosterone Cypionate & 750 iu hCG for 8 weeks. My subcutaneous injection schedule is as follows:

20mg Test C - Monday, Wednesday, Friday, Saturday & Sunday

250 iu hCG - Tuesday, Thursday and Sunday


I have never had acne this bad before. My back and face are very bad right now. I thought it may be the high estradiol, so my doctor prescribed me Anastrozole. The dose was 0.5mg x 3 times per week. I know that is quite high so l've taken 0.25mg twice this week, hoping for some improvement.

If anything, it's gotten worse. I have become extremely self conscious and insecure about the acne. My face and hands are also swollen.

I posted a thread about body acne a few weeks ago. My back was beginning to break out but not horribly, my face was completely fine. Now my back has substantially worsened, and my face has completely broken out.

I am feeling much better mentally and physically since starting TRT. My free test was in the 100s so I felt horrible. I exercise daily, drink a lot of water and mostly eat clean.

I am really hoping I can get this under control. I've tried Clindamycin/Benzoyl Peroxide, Doxycycline and I am now considering Accutane.

I'm hoping someone can share their experiences and maybe some recommendations? I would really appreciate some help.
 

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I have never had acne this bad before. My back and face are very bad right now. I thought it may be the high estradiol, so my doctor prescribed me Anastrozole.
If anything, it's gotten worse. I have become extremely self conscious and insecure about the acne. My face and hands are also swollen.
Testosterone increases aldosterone produced in the adrenal glands, which enters the kidneys, and tells the kidneys to absorb more sodium, ad sodium carries water. This can lead to fluid retention and swelling.

HCG can cause acne, and fluid retention, more so than TRT in isolation.
 
I've tried Clindamycin/Benzoyl Peroxide, Doxycycline and I am now considering Accutane.
No, don't, this can cause loss of libido and erections and can be irreversible. I would not screw with your hormonal pathways using an endocrine disruptor.

Just lower your doses or stop the hCG.
 

hCG Mixing Calculator

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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