Accutane while on TRT?

[Arcane]

Again I wish you the best. I hope your Dr explained how 'tane blocs 5 alpha reductase in tissue which in turn blocks DHT, so it's changing hormones. That's at even .5 mg. I had a MRI on my pitutary after doing 80 mg for 10 days and it said it was "small". The 43 years prior I had zero issues...5 weeks on accutane my life changed forever.

Not trying to scare anyone but if someone explained the real risks in 2010 to me, I would have never used this drug. But once a drug goes generic, the ship has sailed.

Isotretinoin, tetracycline and circulating hormones in acne - PubMed
Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin - PubMed
Sexual complications in people treated with Accutane | RxISK
https://rxisk.org/wp-content/uploads/2018/06/JRS744-2.pdf
https://rxisk.org/wp-content/upload...ition-Sexual-side-effects-of-isotretinoin.pdf

Ill keep you posted. Im almost 10 weeks in now. Feel fine. Libido is still good too. But I'm also taking Ashwagandha

 

[Arcane]

almost 4 months in. main side effects are dry lips, fatigue, eye watering occasionally and sky nostril/nosebleeds.

sex drive is down, but no ED issues currently

 

[Systemlord]

These are huge trade-offs, can you keep this up long-term?

 

[Arcane]

These are huge trade-offs, can you keep this up long-term?

3 more months? I think so. I dont think they’re permanent. The energy thing isnt huge as im ive dealt with much worse and ive been doing jiu jitsu at nights as for libido. Im glad its not high right now personally. ED would be a huge tradeoff but so far not having that. Praying it stays that way. Id say, if my skin stays clear after discontinuing and the energy-related sides go away after my accutane cycle, then yes it was worth it.

Mind you, I have literally exhausted almost every method of staving off acne besides spironolactone, with no success. Accutane allows me to do jiu jitsu again. Get sweaty and not have to worry about major breakouts anymore. Which is huge for me

 

[electrify]

Accutane, Ashwagandha, Spiro etc are all super risky whether on TRT or not, since they all have reports of anhedonia

 

[DaveK22]

Again I wish you the best. I hope your Dr explained how 'tane blocs 5 alpha reductase in tissue which in turn blocks DHT, so it's changing hormones. That's at even .5 mg. I had a MRI on my pitutary after doing 80 mg for 10 days and it said it was "small". The 43 years prior I had zero issues...5 weeks on accutane my life changed forever.

Not trying to scare anyone but if someone explained the real risks in 2010 to me, I would have never used this drug. But once a drug goes generic, the ship has sailed.

Isotretinoin, tetracycline and circulating hormones in acne - PubMed
Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin - PubMed
Sexual complications in people treated with Accutane | RxISK
https://rxisk.org/wp-content/uploads/2018/06/JRS744-2.pdf
https://rxisk.org/wp-content/uploads/2018/10/Citizen-petition-Sexual-side-effects-of-isotretinoin.p

I can't say it anymore than this ^^^
I don't wish this shit on anyone. Wish I had been warned

 

[Arcane]

I can't say it anymore than this ^^^
I don't wish this shit on anyone. Wish I had been warned

Ill get bloodwork after and share here