testosterone

In this episode of the You Are Not Broken Podcast, Dr. Kelly Casperson shares the biggest takeaways from the 2026 ISSWSH Conference (International Society for the Study of Women’s Sexual Health). We cover the latest research on women’s sexual health, hormones, testosterone therapy, and new...

Professor Alan Rogol

* Substantial evidence suggests that sleep disorders may impair testosterone levels, partially improved after specific treatments (for instance: positive airway pressure for OSA). On the other hand, appropriate indications for testosterone replacement therapy (TRT) can alleviate hypogonadism...

I turned 40 back in October. I am not on TRT or any other hormones. I noticed that in the past six months or so that my ejaculate has noticeably decreased. Any thoughts on why that would happen and can I do anything about it?

Hitting the nail on the head here! * More than 30 years later, he argues that the regulatory framework no longer reflects current clinical evidence and may be doing more harm than good. In this episode, Arundhati Parmar interviews Shalin Shah, CEO of Marius Pharmaceuticals, about...

Dr. Janine Davis Overview Conclusion

* The CDC Hormone Standardization Program for Total Testosterone (HoSt-TT) evaluates assay performance against ID-LC-MS/MS using clinically relevant concentrations. * The TSTII assay is CDC HoSt-TT certified, has strong alignment to LC-MS/MS, and shows good correlation of calculated FT with...

Mohit Khera Lifespan, Healthspan and Sexspan Example of someone that lives 81 yrs old Conclusion

This is wild! Low-intensity Pulsed Ultrasound Enhancement of Testosterone Production https://patents.justia.com/patent/20230249005 https://journals.lww.com/ajandrology/fulltext/2021/23060/low_intensity_pulsed_ultrasound_stimulates.9.aspx

Chapters 1:18 What are the implications of the NEJM's new paper on PSA? 5:28 At what age should most men be getting their PSA checked? 7:56 What is the usual "next step" following a high PSA reading? 10:52 What exactly does a high PSA signify? Does it always mean cancer? 14:24 Alex's conclusions

All those so called gurus polluting social media and the half-wits pushing that more T is better mentality bull*** stinkin up those so called men's health/HRT forums! * At the same time, the non-medical environment has evolved, with online marketplaces, informal supply chains, and...

* With more than 40 years of experience, Dr. Burnett has helped shape modern men’s health, pioneering nerve-sparing prostate surgery, advancing nitric oxide research that paved the way for treatments like Viagra, and mentoring physicians around the world...

Dr. Allaire breaks this down! * protecting your erection is protecting your health Eric Allaire Andropause is often presented as the male equivalent of menopause — but this idea is misleading. In this video, I explain why andropause is largely a myth, how testosterone really works...

* “d3-T is a novel, structurally identical form of testosterone where select hydrogen molecules have been substituted with deuterium. This small change creates a significant breakthrough.” * AVA-291 is a “next-generation testosterone designed to retain [testosterone]’s androgen activity while...

In this episode, Dr Louise Newson is joined by urologist and sexual medicine specialist Prof Mohit Khera to talk about testosterone in women and why it remains one of the most misunderstood and underused hormones in medicine. Crucially, this conversation goes far beyond libido. This is a...

For men on testosterone replacement therapy, what benefits and side effects have you personally experienced, and how long did it take to notice changes?

* The findings from TTrials, TRAVERSE, T4DM and other recent studies have provided high-quality evidence of the metabolic benefits and low risk of serious adverse events associated with testosterone therapy. Reflecting this new evidence, the FDA revised its black box warning regarding...

Dr. Anand Patel is a GMC-registered GP and one of the UK's leading experts in men's health, specialising in healthy sexual function, testosterone deficiency, and male fertility. Studies are showing that men are dissatisfied with their penis size and commonly experiencing a wide array of sexual...

Think testosterone is just a male hormone? Think again. In this game-changing conversation, Shalin Shah, CEO of Marius Pharmaceuticals, debunks a major myth in women’s health. Spoiler alert: women have more testosterone than estrogen, and when those levels drop during perimenopause and...

https://kellycaspersonmd.substack.com/p/2026-goals KELLY CASPERSON, MD DEC 29, 2025 The past decade (or 2025 for that matter) has shown that progress in women’s health does not result from being polite, patient, or quiet. It advances when individuals speak uncomfortable truths openly and...

* The investigators plan to explore the direct role of these sex-specific hormones in regulating blood flow to the brain by blocking hormone production in healthy males and females and giving back testosterone and estrogen, respectively. The investigators will then conduct a range of tests to...

Understanding Polycythemia

In this episode, Dr. Brandon and Dr. Morgentaler talk about how emerging research suggests testosterone therapy may not only be safe but could actually help protect against aggressive prostate cancer, while also touching on practical approaches to maintaining sexual connection at midlife...

The FDA encourages the public to comment in docket FDA-2025-N-6743 Expert Panel on Testosterone Replacement Therapy for Men. https://www.federalregister.gov/public-inspection/2025-22466/request-for-information-expert-panel-on-testosterone-replacement-therapy-for-men An unpublished Notice by...

Something is happening to men, and no one is talking about it. Child attachment and parenting expert Erica Komisar reveals how modern society is rapidly stripping men of their traditional roles, leaving many feeling lost, directionless, and disconnected from both their families and their...

Testosterone Saturation Model https://www.nature.com/articles/s41443-025-01206-3 Abstract Testosterone replacement therapy (TRT) remains controversial in men with a history of prostate cancer due to historical concerns regarding oncologic safety. This scoping review aimed to...

In this episode, Dr. Jesse Mills tackles pressing issues surrounding men's health, from the effects of nicotine pouches to the latest in genetic therapy. They discover the role of peptides, explore options for penile health, and face the stigma that often hinders open discussions. The hosts also...

https://www.managedhealthcareexecutive.com/view/optum-rx-removes-reauthorizations-from-an-additional-40-drugs Beginning in January 2026, Optum Rx is removing reauthorizations for two new drug classes: hormone therapies and knee osteoarthritis injectables. Beginning Jan. 1, 2026, Optum Rx, the...

Dr. Davis cutting deep here! 27:30 HRT loses its black box warning 29:29 The harm of over prescribing and big dose HRT There is a lot we don’t know about the menopause. It’s a stage of life that can be difficult to navigate for many women - especially since the advice online is all over...

* These effects can be life-altering and can lead to social withdrawal, relationship strain and reduced capacity to work. With key neurotransmitter systems including serotonin, allopregnanolone and gamma-aminobutyric acid (GABA) being modulated by fluctuating levels of oestradiol, progesterone...

Testosterone for women is one of the most confusing and misunderstood topics in women’s health. In this episode, Dr. Heather Hirsch and Dr. Kelly Casperson explain why women need testosterone, the science behind female testosterone levels, and how testosterone dosing for women actually works. We...