testosterone

Testosterone levels have dropped more than 25% over the past two decades — and the downstream effects on brain health, cardiovascular function, energy, and libido are only beginning to be understood. Leslie sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to go deep on one of the most...

The CMV Paradox Why a Silent Virus May Be Driving the HIV Aging Gap, and What a New Trial Reveals About Closing It A research summary for people living with HIV, clinicians, and advocates Chronic inflammation, not HIV itself, is driving the premature heart disease, cancer, and frailty that...

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Kelly Casperson, a urologist, author, and host of the podcast “You Are Not Broken”. Dr. Casperson trained in a specialty that treats both men and women, which gave her an early and clear view of the gender gap in sexual...

I had been on daily subq injections of T cyp for 7 years. During the entire time, my sleep quality was pretty poor. It would take 30-60 minutes for me to fall asleep. I would wake 1-3 times each night to go to the bathroom (1 was a good night, 3 a bad night). I would average a good 3-4 hour...

https://audioboom.com/posts/8890570-the-other-half-of-fertility-understanding-male-infertility Think infertility is just a women's issue? Think again. In this eye-opening episode of the Modern Parenthood Podcast, Dr. Dorette Noorhasan is joined by Dr. Andrew Sun. A trained urologist who...

https://www.bocaratontribune.com/bocaratonnews/2026/04/assessing-the-decline-in-libido-hormonal-complexity-vascular-health-and-psychosocial-stress/ ED is multifactorial and vascular issues are the most common cause. T plays a small role! * only about 5% or less of erectile dysfunction is...

If you have erectile dysfunction and you’re not sleeping well — or if you’ve never been tested for sleep apnea — this video explains why that matters more than you might think. We break down the three biological mechanisms that connect sleep to erection quality, what obstructive sleep apnea is...

Dr. Neal Shore https://www.urotoday.com/video-lectures/asco-gu-2026/video/5448-psa-control-after-treatment-suspension-embark-data-at-36-months-neal-shore.html Neal Shore discusses EMBARK trial exceptional responders who maintained PSA below 0.2 for approximately three years while recovering...

Key points here! * Genetic variants, including polymorphisms in the androgen receptor (AR) gene, influence individual susceptibility and therapeutic response. Highlights * Androgenetic alopecia (AGA) is the most common form of hair loss, affecting both men and women through a progressive...

* Within the arcuate nucleus, a specialized subset of kisspeptin neurons, known as KNDy (Kisspeptin/Neurokinin B/Dynorphin) cells, functions as a “pulse generator,” coordinating rhythmic bursts of activity that drive the pulsatile release of GnRH [3, 4]. * Three healthy adult men received a...

In this insightful presentation, Dr. Leon Telis examines the evolving evidence behind testosterone replacement therapy (TRT) in men with prostate cancer. Once considered unsafe, TRT is now supported by growing research showing that it can be both safe and beneficial for select patients...

Hey everyone, looking for informed opinions/experiences because I’ve been dealing with this for a while now. Background: 21 years old male Only one testicle (lost the other earlier, long story involving medical negligence which has honestly made me very skeptical of doctors) Remaining...

Hi guys hope you are all well. I have been on trt since 2021.(might of seen my threads) 1st time was absolutely amazing apart from a few hiccups along the way. The 2nd time my body would just not let me tolerate the same dose that I was on before 125mg of sus250 and 250iu hcg 2x week. Im...

In this crucial episode, host Dr. Ray Christensen is joined by experts to dive into the most common and critical topics in men's health, including prostate issues, testosterone, lifestyle, and sexual health. We answer your call-in questions live and break down complex medical terms like LUTS...

In this episode, Dr Louise Newson is joined by urologist, educator and hormone health advocate Dr Kelly Casperson to challenge some of the most persistent myths surrounding testosterone and women’s health. Drawing on both clinical experience and scientific evidence, they explore why testosterone...

Conclusions

In this episode of the You Are Not Broken Podcast, Dr. Kelly Casperson shares the biggest takeaways from the 2026 ISSWSH Conference (International Society for the Study of Women’s Sexual Health). We cover the latest research on women’s sexual health, hormones, testosterone therapy, and new...

Professor Alan Rogol

* Substantial evidence suggests that sleep disorders may impair testosterone levels, partially improved after specific treatments (for instance: positive airway pressure for OSA). On the other hand, appropriate indications for testosterone replacement therapy (TRT) can alleviate hypogonadism...

I turned 40 back in October. I am not on TRT or any other hormones. I noticed that in the past six months or so that my ejaculate has noticeably decreased. Any thoughts on why that would happen and can I do anything about it?

Hitting the nail on the head here! * More than 30 years later, he argues that the regulatory framework no longer reflects current clinical evidence and may be doing more harm than good. In this episode, Arundhati Parmar interviews Shalin Shah, CEO of Marius Pharmaceuticals, about...

Dr. Janine Davis Overview Conclusion

* The CDC Hormone Standardization Program for Total Testosterone (HoSt-TT) evaluates assay performance against ID-LC-MS/MS using clinically relevant concentrations. * The TSTII assay is CDC HoSt-TT certified, has strong alignment to LC-MS/MS, and shows good correlation of calculated FT with...

Mohit Khera Lifespan, Healthspan and Sexspan Example of someone that lives 81 yrs old Conclusion

This is wild! Low-intensity Pulsed Ultrasound Enhancement of Testosterone Production https://patents.justia.com/patent/20230249005 https://journals.lww.com/ajandrology/fulltext/2021/23060/low_intensity_pulsed_ultrasound_stimulates.9.aspx

Chapters 1:18 What are the implications of the NEJM's new paper on PSA? 5:28 At what age should most men be getting their PSA checked? 7:56 What is the usual "next step" following a high PSA reading? 10:52 What exactly does a high PSA signify? Does it always mean cancer? 14:24 Alex's conclusions

All those so called gurus polluting social media and the half-wits pushing that more T is better mentality bull*** stinkin up those so called men's health/HRT forums! * At the same time, the non-medical environment has evolved, with online marketplaces, informal supply chains, and...

* With more than 40 years of experience, Dr. Burnett has helped shape modern men’s health, pioneering nerve-sparing prostate surgery, advancing nitric oxide research that paved the way for treatments like Viagra, and mentoring physicians around the world...

Dr. Allaire breaks this down! * protecting your erection is protecting your health Eric Allaire Andropause is often presented as the male equivalent of menopause — but this idea is misleading. In this video, I explain why andropause is largely a myth, how testosterone really works...

* “d3-T is a novel, structurally identical form of testosterone where select hydrogen molecules have been substituted with deuterium. This small change creates a significant breakthrough.” * AVA-291 is a “next-generation testosterone designed to retain [testosterone]’s androgen activity while...

In this episode, Dr Louise Newson is joined by urologist and sexual medicine specialist Prof Mohit Khera to talk about testosterone in women and why it remains one of the most misunderstood and underused hormones in medicine. Crucially, this conversation goes far beyond libido. This is a...