testosterone

For those of us with average T levels and/or higher SHBG, our bodies are producing enough T, they just aren't using what's there because it is being bound by SHBG and isn't bioavailable. Why hasn't the pharmaceutical industry focused on producing medications that control (increase/decrease)...

Hi guys, i am new here. I am a young man in his 20's and i have primary hypogonadism induced by a long steroids cycle without the use of HCG. In fact, 5 years ago, i did a Blast and Cruise for 1 year straight. I only used testosterone cypionate at 700mg/week during blast and 200mg/week during...

Hi all, Been on trt about 5 years. Bloodwork been stable for quite a while now. Happy with how everything is going. Recently I changed from luer lock syringes to 27g insulin syringes for my testosterone shots. Been thinking about it, when i used to use the old syringes there would be a tiny...

Has anyone experienced eczema like skin issues while on TRT? I don't mean injection site issues like redness and inflammation but systemic hive like, extremely itchy raised lesions on the back, chest, right and left flank. I have been off TRT for a few months now and the issue has increased. The...

Previously, on 100 mg, weekly, my free T was 225. Changed up after two months because I was feeling depleted five days out. Went to MWF, 34 mg, IM. Latest labs through Discounted showed a decrease in total(1064 to 1032) with free T down to 191. Now doing 40 mg, MWF and will recheck in six or...

Just throwing another question to the masses. I am currently into my third week of Clomid only, post a two month (or so) duration of self administered TRT (75mg weekly test-e). I started a week after my last injection with 12.5mg of Clomid daily (week 1) then upped it to 25mg daily from week 2...

My general doctor just prescribed me Trazodone to help with sleep. I've been on TRT for 2yrs through my clinic and I just want to verify that It's "safe" to take a low dose of Trazodone 50mg while on TRT? Thanks in advance!

History of testosterone therapy through the ages (2022) Mary Rostom, Ranjith Ramasamy, and Taylor P. Kohn The symptoms of testosterone deficiency have been known throughout history with evidence dating back to the twenty-first century BCE when men were castrated to be docile and obedient...

So I heard somewhere that 100mg of testosterone isn’t actually 100mg but a lower percentage is this true and how much would it be if it was cypionate in particular ? Thanks you guys !

So I’ve been doing daily IM shots and I must say I’ve gotten great results but I’m getting tired of how long and far I have to inject into my body and I hear subQ is so much easier especially with low amounts of testosterone. Is there anyone who has switched and gotten the same results or better...

There be a minority of people who simply don't "respond" (no benefits, you feel no different) to testosterone, no matter the protocol, at least the one's you've tried so far. What's your plan now? Have you given up and just accepted life as is? Are you still testing protocols hoping one day...

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I have heard that not using HCG concurrently with TRT will cause shrikage of improtant testicular cells and death over time. Rendering the balls damaged. I have also heard that HCG is not necessary if one does not feel good on it. And we can regain fertility just by adding a fertility...

I am currently on 100mg/week Test Cypionate, and .25mg Analtrozole same day. My body is more hairy than ever since I got on TRT. But I am seeing more hair thining on my head. Hair gets longer but hair is thining on my head. Little hair loss specially on sides on forehead. I am in my low's 40...

Hi all, I'd like some advice on reducing my testosterone dosage. Please by all means, treat me like the idiot I am because I still have much to learn. Below is my latest blood test results (as of yesterday). Testosterone translates to 946ng/dl and E2 to 31.3 pg/ml. From what I understand...

So I don’t want the medical technical Mumbo jumbo about it’s a carrier protein and all but what I want to know is if someone has low shbg what do they feel like . Should they feel tired , not optimized , workouts suck ,low sex drive, recovery ect . Does having normal levels make you feel better ?

First off I want to thank everyone who has helped me over the years with my protoco. But it seems to be like I am beating my head against the wall. I have hypogandis, 52, 5’8 155lbs and fit. I’m an epileptic who gets crushed by insomnia, which in turn causes seizures. Recently I have been...

Hi all, I posted a month ago about my trials an tribulations regarding my sweet spot was with high T 210mg/week and very low E < 5. only happy when estradiol is VERY low At that point I felt like conquering a small country over the weekend. Though my last nurse had approved it, my new nurse...

Has anyone tried navel transdermal testosterone application? This study Navel absorption: transdermal bioavailability of testosterone shows bioavailability of 79.9% compared to 49.9% forearm administration.

https://pubmed.ncbi.nlm.nih.gov/34661247/ Eur Rev Med Pharmacol Sci . 2021 Oct;25(19):5889-5903. doi: 10.26355/eurrev_202110_26865. Low testosterone levels and high estradiol to testosterone ratio are associated with hyperinflammatory state and mortality in hospitalized men with COVID-19 M...

Maybe someone here can advise me on where and how to proceed next. Perhaps there is some obscure hormone level or something else that the doctors have neglected to test for that would unlock the mystery of my condition. I am in despair that I will ever get an answer, much less any treatment. I...

Hello all. As the title states, I'm starting TRT and my doctor has prescribed 200 of mg of test cyp. / wk. I'm actually going to the clinic tomorrow so that they can show me how to self-administer. Good times ahead (I hope)! I'm not a gymhead these days, but have some leftover muscle from when...

Hi all, Wanted to know if anyone knew this. I'm aware that likely genital skin/scrotum is richest in 5a-reductase and thus yields the most DHT from topical testosterone (gel or cream). Does anyone know which site comes after that? From what I've read the sheer amount of skin you apply on...

If anybody's wondering whether this can be done without burning.. I've tried pouring a thin layer of testosterone gel onto aluminum paper, let it stay out for around.. 2-3 hours, then apply to the balls. The idea is to let some of the ethanol evaporate. And why I do this.. I can't get the...

Hi, There is a compounding pharmacy where I live but they don't know how to make testosterone cream. Does anyone have a formula / composition that I can send to them as reference?

Hi, I just got my blood work done with Quest Diagnostic and wanted to share some results. I inject Enanthate every day (10cc) subq, (170mg a week total), and take .5mg Anastrozole Mon/Wed/Friday. Total T: 1442 Free T: 524 E2: 32 (just a little high). My blood pressure is high, so I went to my...

There is a lot of information online about working out being good for testosterone production, while in the other hand it can actually be bad for it. I've been trying to research for information regarding this, and how much would actually be optimal for hormonal functions. Does anyone have...

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Hi, I hope all is well. I know that testosterone plays a significant role in the production and regulation of neurotransmitters such as dopamine, serotonin, GABA etcetera. If testosterone levels are low for an individuals physiological state then this can ofcourse cause social anxiety...

Sorry if this question is already floating out there in another thread. I couldn't find it. Wondering who y'all use for TRT replacement and hormone optimization care. I know Defy is a big one used by many. Are there others I might consider? Who do YOU (yes, you reading this) use? Do you...