testosterone

  1. madman

    He Lost His Drive. Is It His Testosterone?

    You've watched him pull away and wondered if something is actually wrong with his body — and you were right to wonder. Dr. Arthur Burnett, Johns Hopkins urologist, breaks down exactly what testosterone does (and doesn't) do for men's drive, erections, and mood — and why a basic blood test isn't...
  2. madman

    Understanding the Peptide Movement in Men’s Health, with Larry Lipschultz, MD

    In this episode of Pearls & Perspectives, Amy Pearlman, MD, is joined by Larry I. Lipschultz, MD, to discuss the growing interest in peptides, including their potential applications in men’s health, evolving regulatory landscape, and what urologists need to know as patient demand continues to...
  3. madman

    Testosterone Treatment in Prediabetes and Obesity: Cases and Review of Literature

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  4. madman

    The interplay between testosterone and depression: bridging research, clinical applications, and health

    * Overall, the available evidence suggests that TRT may provide clinically meaningful improvements in mood for hypogonadal men, particularly those with low baseline testosterone and coexisting depressive symptoms. However, current data do not support its routine use as an antidepressant therapy...
  5. madman

    How Does the Penis Change With Age - and What Can Men Do About It?

    Curated By Nelson Vergel | ExcelMale.com | Updated May 2026 Most men assume their penis will stay exactly as they remember it from their 20s. Then, somewhere in their 40s or 50s, things start to feel different. The erections are not quite as firm, morning wood has become less reliable, and a...
  6. madman

    Testosterone Levels Improve in Men under GLP-1 Receptor Agonist Therapy

    Dr. Andres Guillen Lozoya discusses findings from, "Testosterone Levels Improve in Men under GLP-1 Receptor Agonist Therapy.” This study aimed to evaluate changes in total and free testosterone before and after GLP-1RA therapy in men
  7. madman

    Clinical Implications of Minipuberty

    * In male infants, luteinizing hormone (LH) and testosterone during minipuberty are present at levels similar to those in adults but subsequently become undetectable. This phenomenon was shown in infant boys more than 50 years ago. https://www.nejm.org/doi/full/10.1056/NEJMra2305989
  8. madman

    Holistic approach to male LUTS

    Speakers: Prof. J-N.L. Cornu (FR) Dr. M. Tutolo (IT) Dr. D. Elterman (CA) M. Creta, Naples (IT) This recording explores a holistic, patient-centred approach to male lower urinary tract symptoms (LUTS) beyond single-symptom treatment strategies. Male LUTS are common, heterogeneous, and...
  9. madman

    Sun Pharma signs Definitive Agreement to Acquire Organon

    Mumbai, India, April 27, 2026 and Jersey City, New Jersey, April 26, 2026 – Sun Pharmaceutical Industries Limited (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: SUNPHARMA, BSE: 524715) (together with its subsidiaries and/or associated companies, “Sun Pharma”) and Organon & Co. (NYSE: OGN)...
  10. madman

    Testosterone Recovery Dynamics After Short-Term ADT for Localized Prostate Cancer

    * Dr. Tombal recommends relugolix, an oral GnRH antagonist that restores normal testosterone within 90 to 120 days, when ADT is required, and notes that patients who fail to recover normal testosterone have worse prognosis. * He also supports testosterone supplementation in symptomatic...
  11. madman

    Higher Testosterone for Postmenopausal Women on HRT? Study Suggests ~78 ng/dL Total Testosterone Target

    Abstract INTRODUCTION AND OBJECTIVES: Testosterone replacement therapy (TRT) is an established treatment for hyposexual desire in postmenopausal women, yet the broader effects of TRT on menopausal symptoms remain uncertain. Our research aims to define optimal testosterone levels for symptomatic...
  12. madman

    Testosterone Replacement Therapy - Experts Discuss - safety (hematocrit/CVD), efficacy, formulation selection

    * Panelists address the risk of polycythemia associated with testosterone therapy, particularly injectable formulations, and emphasize the importance of monitoring hematocrit changes relative to baseline values rather than absolute thresholds alone Moderated by Manoj Monga, MD, FACS...
  13. madman

    Vasectomy Reversal Leads to Couple's Restored Fertility with Dr. Larry Lipshultz

    https://www.urologyhealth.org/healthy-living/urology-care-podcast/sexual-health-podcasts/vasectomy-reversal-leads-to-couples-restored-fertility-with-dr-larry-lipshultz
  14. madman

    Sex Hormone Influences on Venous Thrombotic and Cardiovascular Risk

    https://www.nejm.org/doi/abs/10.1056/NEJMra2202438
  15. madman

    One of the most stigmatized and misunderstood hormones in medicine

    Testosterone levels have dropped more than 25% over the past two decades — and the downstream effects on brain health, cardiovascular function, energy, and libido are only beginning to be understood. Leslie sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to go deep on one of the most...
  16. madman

    CMV, Inflammation, and Aging in Treated HIV

    The CMV Paradox Why a Silent Virus May Be Driving the HIV Aging Gap, and What a New Trial Reveals About Closing It A research summary for people living with HIV, clinicians, and advocates Chronic inflammation, not HIV itself, is driving the premature heart disease, cancer, and frailty that...
  17. madman

    Sexual Health, Libido, and Orgasm: What Medicine Missed

    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Kelly Casperson, a urologist, author, and host of the podcast “You Are Not Broken”. Dr. Casperson trained in a specialty that treats both men and women, which gave her an early and clear view of the gender gap in sexual...
  18. V

    Sleeping much better on Kyzatrex vs injections

    I had been on daily subq injections of T cyp for 7 years. During the entire time, my sleep quality was pretty poor. It would take 30-60 minutes for me to fall asleep. I would wake 1-3 times each night to go to the bathroom (1 was a good night, 3 a bad night). I would average a good 3-4 hour...
  19. madman

    The Other Half of Fertility: Understanding Male Infertility

    https://audioboom.com/posts/8890570-the-other-half-of-fertility-understanding-male-infertility Think infertility is just a women's issue? Think again. In this eye-opening episode of the Modern Parenthood Podcast, Dr. Dorette Noorhasan is joined by Dr. Andrew Sun. A trained urologist who...
  20. madman

    Assessing the Decline in Libido: Hormonal Complexity, Vascular Health, and Psychosocial Stress

    https://www.bocaratontribune.com/bocaratonnews/2026/04/assessing-the-decline-in-libido-hormonal-complexity-vascular-health-and-psychosocial-stress/ ED is multifactorial and vascular issues are the most common cause. T plays a small role! * only about 5% or less of erectile dysfunction is...
  21. madman

    Why Bad Sleep Is Destroying Your Erection

    If you have erectile dysfunction and you’re not sleeping well — or if you’ve never been tested for sleep apnea — this video explains why that matters more than you might think. We break down the three biological mechanisms that connect sleep to erection quality, what obstructive sleep apnea is...
  22. madman

    PSA Control After Treatment Suspension: EMBARK Data at 36 Months

    Dr. Neal Shore https://www.urotoday.com/video-lectures/asco-gu-2026/video/5448-psa-control-after-treatment-suspension-embark-data-at-36-months-neal-shore.html Neal Shore discusses EMBARK trial exceptional responders who maintained PSA below 0.2 for approximately three years while recovering...
  23. madman

    Pathophysiology of Androgenetic Alopecia and Implications for Treatment

    Key points here! * Genetic variants, including polymorphisms in the androgen receptor (AR) gene, influence individual susceptibility and therapeutic response. Highlights * Androgenetic alopecia (AGA) is the most common form of hair loss, affecting both men and women through a progressive...
  24. madman

    Dynamic Modulation of LH Secretion by Continuous Kisspeptin Infusion in Healthy Men

    * Within the arcuate nucleus, a specialized subset of kisspeptin neurons, known as KNDy (Kisspeptin/Neurokinin B/Dynorphin) cells, functions as a “pulse generator,” coordinating rhythmic bursts of activity that drive the pulsatile release of GnRH [3, 4]. * Three healthy adult men received a...
  25. madman

    Restoring Balance: Exploring Testosterone Replacement in Prostate Cancer

    In this insightful presentation, Dr. Leon Telis examines the evolving evidence behind testosterone replacement therapy (TRT) in men with prostate cancer. Once considered unsafe, TRT is now supported by growing research showing that it can be both safe and beneficial for select patients...
  26. T

    21 y.old male, one testicle, post-varicocelectomy – considering TRT + hCG (fertility concerns)

    Hey everyone, looking for informed opinions/experiences because I’ve been dealing with this for a while now. Background: 21 years old male Only one testicle (lost the other earlier, long story involving medical negligence which has honestly made me very skeptical of doctors) Remaining...
  27. whiting1986

    DHEA & PREGNENOLONE SUCCESS STORIES

    Hi guys hope you are all well. I have been on trt since 2021.(might of seen my threads) 1st time was absolutely amazing apart from a few hiccups along the way. The 2nd time my body would just not let me tolerate the same dose that I was on before 125mg of sus250 and 250iu hcg 2x week. Im...
  28. madman

    Prostate, Testosterone, & LUTS Explained

    In this crucial episode, host Dr. Ray Christensen is joined by experts to dive into the most common and critical topics in men's health, including prostate issues, testosterone, lifestyle, and sexual health. We answer your call-in questions live and break down complex medical terms like LUTS...
  29. madman

    Testosterone and women's health: breaking the stigma

    In this episode, Dr Louise Newson is joined by urologist, educator and hormone health advocate Dr Kelly Casperson to challenge some of the most persistent myths surrounding testosterone and women’s health. Drawing on both clinical experience and scientific evidence, they explore why testosterone...
  30. madman

    Testosterone Replacement Therapy and Prostate Cancer

    Conclusions
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