E2 rebound

Zooulie12

Member
So I was stupid. About a month ago my doctor told me to stop taking my AI because my last labs showed my e2 was 28 (roche test) On Monday of this week I felt my e2 was getting high (since I had not taken my AI in over a month) so I took my past dose of my AI .25 on Monday. Anyways I bottomed out. Can’t get it up even with cialis. Fatigued even after 10 hrs of sleep: wondering how long recovery takes. I am also curious. If I stay off the AI permanently at some point won’t my e2 creep up high again? I do sub Q injections Monday and Thursday. Dose is 60mg twice a week. My body fat btw is very low. I say that because I was wondering if that has to do at all with your body holding more e2? Thanks!
 
Also normally after a work out I am not sore at all the next day. This week my muscles have been sore all week after a week. Are there people on here who don’t take an AI and who are on like a higher dose of testosterone then I am?
 
It would be a huge leap to even to get to thinking that 1, .25mg dose crashed your E, but given you have no labs and the one you do have is the wrong test, I'm not sure what else can be said.
 
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It would be a huge leap to even to get to thinking that 1, .25mg dose crashed your E, but given you have no labs and the one you do have is the wrong test, I'm not sure what else can be said.
Well it’s crashed my e2 before. My last labs when it crashed was TT 1040 E2- undectable and that was when I was taking just .25 once a week. So I am probably just sensitive to anastrolze. My biggest question is how long rebounds take? And if people can do trt without an AI.
 
It would be a huge leap to even to get to thinking that 1, .25mg dose crashed your E, but given you have no labs and the one you do have is the wrong test, I'm not sure what else can be said.
And my labs 2 weeks ago, to see how things were going. My TT was 890. E2-28. With sub q injections can your e2 stay at a normal amount. All I know is that with the roche test. E2 of 28 is probably still considered low on the sensitive
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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