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Subcutaneous Testosterone Injections: The Complete Guide for Men on TRT
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Are you tired of painful intramuscular injections and wondering if there's a more comfortable way to administer your testosterone replacement therapy? For decades, intramuscular (IM) injections have been the standard method for testosterone...
Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options
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By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier...
Fewer than half of HIV+ men found to have low testosterone are treated with TRT
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This nationwide study examines the prevalence of testosterone deficiency and the subsequent use of replacement therapy among men living with HIV. By analyzing data from over 100 million patients, researchers discovered that healthcare providers...
SteroidPlotter Guide: Understanding mg/Day, Ester Weights & True Testosterone Dosing
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How Much Testosterone Are You Actually Getting From Your TRT Protocol? If you're on testosterone replacement therapy (TRT), you've probably used a steroid calculator or plotter to visualize your dosing protocol. But here's a critical question...

US Federal and State Regulations on Testosterone and HCG

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Testosterone is a controlled substance in the US, specifically a Schedule-III controlled substance (in all but one State), and this includes any form of testosterone including injectable, transdermal, patches, pellets, and any compound or product...
Key Historical Failures and Lessons Learned from Attempts to Get a Testosterone Product FDA-Approved for Women
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FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
HCG Use in Men on TRT or as Monotherapy: Over 200 Questions and Answers
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I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...
Upcoming FDA Expert Panel on Testosterone Replacement Therapy for Men
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@Nelson Vergel We need you here! https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025 Location: FDA White Oak Campus, 10903 New Hampshire Ave., Building 31, Great Room, Silver...
Practical Clinical Summary on Testosterone Therapy in Women
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Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological...
How Anabolic Agents Can Save Your Muscles: One Man's Journey from Death Sentence to Thriving at 66
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Can testosterone and anabolic agents reverse muscle wasting? This is the story of how hormone therapy transformed HIV treatment—and what it means for men's health today. Nelson Vergel was diagnosed HIV-positive in 1985 when it was a death...
https://www.defymedical.com/get-started/.
How to Find a Good Doctor that Prescribes Testosterone Plus hCG: TRT Near Me
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Looking for a qualified TRT doctor who prescribes testosterone and HCG? Finding the right physician can make or break your hormone optimization journey. Many doctors are poorly trained in testosterone replacement therapy—they under-dose, skip...
Options for Delayed or Absent Orgasms Despite Stimulation in Men
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Experiencing delayed orgasm or anorgasmia on TRT? Many men on testosterone therapy report difficulty reaching climax despite normal erections and libido. This frustrating issue is more common than most realize—and it's often treatable once you...

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