TRT

The Evolution of Testosterone Products in the U.S. (1935-2025)
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Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early...
Shifting the Testosterone Treatment Paradigm with Oral Testosterone (Kyzatrex)
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Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape...
Testosterone Replacement Therapy (TRT) Facts Every Man Should Know
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Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...
Smoking Cessation's Effects on Male Hormonal Levels
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This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
Where to get Testosterone prescriptions?
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Been on TRT for almost two years. It's been life changing. I take .9 to 1cc per week of Enanthate injected. Took a while to dial it in, but 800 to 1000 seems to be the sweet spot for me. Then primary care physician retired, new guy want's it to...
Testosterone Therapy Induced High Hematocrit- Can Therapeutic Phlebotomy Be a Double-Edged Sword?
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https://ec.bioscientifica.com/view/journals/ec/aop/ec-24-0283/ec-24-0283.xml Therapeutic Phlebotomy: A Double-Edged Sword? Current Guidelines: "Several endocrine organizations mention therapeutic phlebotomy as a means of treating TTh–induced...
Where to Inject Testosterone: Intramuscular vs. Subcutaneous Injections
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No matter what kind of TRT your doctor has given you, a common question is where to inject testosterone. For decades, most men have injected their testosterone intramuscularly (IM), primarily into the glutes, quadriceps, or deltoids, using a 1 to...
Testosterone blood level is correlated with immune cell abundance in transgender young people on gender affirming hormones
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Sex hormones like estrogen and testosterone don’t just affect things like body shape or voice—they also play a role in how the immune system works. This is especially important for transgender people who take these hormones as part of their...
The TRT Guide from ExcelMale.com
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Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...
What Every Man Needs to Know | Testosterone 101
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Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...
Regular testosterone test overestimates hypogonadism in men compared to the LC-MS/MS assay
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* IA compared to LC-MS/MS in hypogonadal men overestimates significantly both the prevalence of biochemical Hy and TRT compensation both for TT and cfT. These results highlight the role of LC-MS/MS and SHBG assessments in every day clinical...
The FDA Was WRONG About Testosterone? Major Label Update Explained
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In this episode, Dr. Morgentaler and Dr. Brandon talk about the FDA finally reversing its stance on testosterone risks, what that means for heart health, and why it’s a big win for science—and for patients. Chapters 00:07 – FDA's New Stance...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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