My question might be a basic one, but what is the purpose of Sex Hormone Binding Globulin (SHBG)? In general terms I appreciate that SHBG binds to Total Testosterone (along with Albumin) to give us Free Testosteron. My question is not about...
In an insightful interview from the "Dr. Gabrielle Lyon" YouTube channel, Dr. Larry Lipshultz, a renowned expert in male reproductive health, discusses the alarming global decline in male fertility, attributing it to factors such as obesity...
Briefing Document: Estradiol in Men on TRT Source: Excerpts from "High Estradiol in Men on TRT: What to Do" by Nelson Viegel (excelmale.com) 1. The Role and Importance of Estradiol in Men Core Idea: Estradiol, often misconstrued as a solely...
* Probably the most challenging forms to quantify, due to their relatively low concentrations are the so called free forms. The free forms of all the hormones (shown in Figs. 1–3) are the hormones not bound to proteins, or conjugated to other...
Download slides (from my book "Beyond Testosterone"): Estradiol in Men Slides Estradiol in Men: The Stigma In the 2014 film The Other Woman, Cameron Diaz, Leslie Mann, and Kate Upton, portray three jilted females who discover they are...
Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...
I am very pleased to announce that I finally finished my full color 427-page booK: The Table of Contents of "Beyond Testosterone" is meticulously organized into detailed sections, each addressing key aspects of testosterone therapy...
Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...
Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...
* IA compared to LC-MS/MS in hypogonadal men overestimates significantly both the prevalence of biochemical Hy and TRT compensation both for TT and cfT. These results highlight the role of LC-MS/MS and SHBG assessments in every day clinical...
High Hematocrit Caused by Testosterone Replacement Therapy By Nelson Vergel, B.S.Ch.E., M.B.A. High hematocrit occurs when there is an excessive production of red blood cells. High hematocrit can cause the blood to become very viscous or...
Background: Please read this previous article: https://www.excelmale.com/threads/heart-palpitations-and-afib-in-older-men-on-testosterone-signals-from-traverse.28247/ New Data...