Using hCG in Men on Testosterone Replacement Therapy (TRT) – A Clinical Review Introduction Exogenous testosterone replacement therapy (TRT) can profoundly suppress the hypothalamic-pituitary-gonadal (HPG) axis through negative feedback. By...
Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early...
Doc just prescribed me 100mg weekly of Deca for joint pain and a bad shoulder. my current protocol is Test Cyp 180mg weekly (pin eod). I am a seasoned lifter. 38 years old. about 12% bf. Pull 500 pound deadlifts for reps. Since starting TRT...
Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape...
Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...
This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...
Hi all, I've been experimenting with pregnenolone for over a year now, with varied success. I seem to get benefits at 100mg (such as higher libido, more pronounced nighttime erections and better sleep); however, I don't get these results...
Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...
Hello all, I’m 28yo male in the US. When I was in my early 20s, I had a residual puffy nipple from puberty. I was very self conscious about this, being pretty deep in weight lifting, and my primary care physician prescribed an anti-estrogen...
38M who has been on TRT + HCG for ~5 years or so. I wanted to see if I could restart production with the help of enclomiphene, as prior to TRT I had a great response to clomid but could not handle the estrogen related sides. I started 12.5mg ED...