SUMMARY: This comprehensive article examines the combination of testosterone replacement therapy (TRT) with GLP-1 medications like semaglutide and tirzepatide for men managing both low testosterone and obesity or type 2 diabetes. Research...
This nationwide study examines the prevalence of testosterone deficiency and the subsequent use of replacement therapy among men living with HIV. By analyzing data from over 100 million patients, researchers discovered that healthcare providers...
Clascoterone 5% Topical Solution for Male Androgenetic Alopecia Overview Clascoterone 5% topical solution represents what could be the first genuinely novel therapeutic mechanism for male pattern hair loss in over three decades. Cosmo...
How Much Testosterone Are You Actually Getting From Your TRT Protocol? If you're on testosterone replacement therapy (TRT), you've probably used a steroid calculator or plotter to visualize your dosing protocol. But here's a critical question...
FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
Melatonin's Role in Reproductive Health and Fertility Executive Summary Melatonin (N-acetyl-5-methoxytryptamine), a neurohormone primarily known for regulating circadian rhythms, demonstrates profound and multifaceted effects on male and female...
I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...
Starting a family with a partner that you love is one of the most magical and exciting experiences that you will ever encounter. It is also daunting and very intimidating, but ultimately, becoming a parent will change you for the better. Sadly...
Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological...
Can testosterone and anabolic agents reverse muscle wasting? This is the story of how hormone therapy transformed HIV treatment—and what it means for men's health today. Nelson Vergel was diagnosed HIV-positive in 1985 when it was a death...
Experiencing delayed orgasm or anorgasmia on TRT? Many men on testosterone therapy report difficulty reaching climax despite normal erections and libido. This frustrating issue is more common than most realize—and it's often treatable once you...
Can statins cause erectile dysfunction? This is a common concern for men taking cholesterol-lowering medications. The research is mixed—some studies suggest statins may actually improve erectile function by enhancing blood flow, while others...