Nelson Vergel

Nelson Vergel

Nelson Vergel

Subcutaneous Testosterone Injections: The Complete Guide for Men on TRT
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Are you tired of painful intramuscular injections and wondering if there's a more comfortable way to administer your testosterone replacement therapy? For decades, intramuscular (IM) injections have been the standard method for testosterone...
Anastrozole for Men: The Complete Evidence-Based Guide for Testosterone Therapy
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By Nelson Vergel | ExcelMale.com | Updated December 2025 Introduction Should you take an aromatase inhibitor with testosterone replacement therapy? This question has sparked considerable debate in men's health circles, with some clinics routinely...
It's Not Just Low T: 5 Surprising Reasons Your Sex Drive Is Low
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The Libido Misconception For most men, a lagging sex drive triggers an immediate, single-minded thought: "It must be my testosterone." While T is a key player in male vitality, this assumption often misses the mark entirely. Libido is far more...
Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options
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By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier...
Sexual Function on TRT: Why Testosterone Alone May Not Be Enough for Erectile Function
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Many men begin testosterone replacement therapy expecting their sexual function to improve across the board—better libido, stronger erections, enhanced satisfaction. And while TRT often delivers significant benefits for desire and overall sexual...
Testosterone and Your Heart: What a Major New Study Really Found
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Summary: The TRAVERSE trial, a landmark FDA-mandated study involving over 5,200 men, has definitively concluded that testosterone replacement therapy (TRT) does not increase the risk of major cardiovascular events like heart attacks, strokes, or...
TRT and GLP-1 Medications: What Men Need to Know About Combining Testosterone Therapy with Semaglutide and Tirzepatide
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SUMMARY: This comprehensive article examines the combination of testosterone replacement therapy (TRT) with GLP-1 medications like semaglutide and tirzepatide for men managing both low testosterone and obesity or type 2 diabetes. Research...
Fewer than half of HIV+ men found to have low testosterone are treated with TRT
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This nationwide study examines the prevalence of testosterone deficiency and the subsequent use of replacement therapy among men living with HIV. By analyzing data from over 100 million patients, researchers discovered that healthcare providers...
New Hair Loss Treatment Safer than Finasteride?: Clascoterone 5% Topical Solution
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Clascoterone 5% Topical Solution for Male Androgenetic Alopecia Overview Clascoterone 5% topical solution represents what could be the first genuinely novel therapeutic mechanism for male pattern hair loss in over three decades. Cosmo...
SteroidPlotter Guide: Understanding mg/Day, Ester Weights & True Testosterone Dosing
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How Much Testosterone Are You Actually Getting From Your TRT Protocol? If you're on testosterone replacement therapy (TRT), you've probably used a steroid calculator or plotter to visualize your dosing protocol. But here's a critical question...
Key Historical Failures and Lessons Learned from Attempts to Get a Testosterone Product FDA-Approved for Women
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FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
Melatonin's Role in Reproductive Health and Fertility
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Melatonin's Role in Reproductive Health and Fertility Executive Summary Melatonin (N-acetyl-5-methoxytryptamine), a neurohormone primarily known for regulating circadian rhythms, demonstrates profound and multifaceted effects on male and female...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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