Testosterone Products in Canada - (oral, nasal, transdermal, injectable)

Big pharma transdermal T patch Androderm manufactured by Allergan Inc. was discontinued back in 2018!

Big pharma brand name Andriol (oral TU) manufactured by Merck was also discontinued back in 2018 and more recently 2024 our beloved Delatestryl (testosterone enanthate) manufactured by Valeant has been discontinued.

The only oral TU available is the generic PMS-Testosterone and Taro-Testosterone capsules.

Come 2025 we may have the option to use the newer versions of oral TU Kyzatrex or Tlando which are available in the US as Marius Pharmaceuticals and Verity Pharmaceuticals are currently seeking approval from Health Canada!

The only injectable TE available is the recently approved generic Hikma testosterone enanthate although it looks as though there is going to be an ongoing shortage in the market!

For injectable TC we still have big pharma Depo-Testosterone manufactured by Pfizer or generic Taro-Testosterone Cypionate.

Main downfall here is they are both only available in the 100 mg/mL strength!

When it comes to transdermal T we still have big pharma Androgel manufactured by BGP Pharma ULC and the generic Taro-Testosterone gel or brand Testim gel manufactured by Paladin Labs Inc.

Downfall here is the strengths are low compared to compounded transdermal gels/creams.

Luckily we still have the option of seeking out compounded transdermal or injectable T.

We also still have nasal T gel Natesto manufactured by Acerus Biopharma Inc but they are on shaky ground!

Sorry bros but the short-acting injectable TP (testosterone propionate) will never be available so your only option would be seeking out a UGL source!




Screenshot (40200).png








 
Big pharma transdermal T patch Androderm manufactured by Allergan Inc. was discontinued back in 2018!

Big pharma brand name Andriol (oral TU) manufactured by Merck was also discontinued back in 2018 and more recently 2024 our beloved Delatestryl (testosterone enanthate) manufactured by Valeant has been discontinued.

The only oral TU available is the generic PMS-Testosterone and Taro-Testosterone capsules.

Come 2025 we may have the option to use the newer versions of oral TU Kyzatrex or Tlando which are available in the US as Marius Pharmaceuticals and Verity Pharmaceuticals are currently seeking approval from Health Canada!

The only injectable TE available is the recently approved generic Hikma testosterone enanthate although it looks as though there is going to be an ongoing shortage in the market!

For injectable TC we still have big pharma Depo-Testosterone manufactured by Pfizer or generic Taro-Testosterone Cypionate.

Main downfall here is they are both only available in the 100 mg/mL strength!

When it comes to transdermal T we still have big pharma Androgel manufactured by BGP Pharma ULC and the generic Taro-Testosterone gel or brand Testim gel manufactured by Paladin Labs Inc.

Downfall here is the strengths are low compared to compounded transdermal gels/creams.

Luckily we still have the option of seeking out compounded transdermal or injectable T.

We also still have nasal T gel Natesto manufactured by Acerus Biopharma Inc but they are on shaky ground!

Sorry bros but the short-acting injectable TP (testosterone propionate) will never be available so your only option would be seeking out a UGL source!




View attachment 48145











00:29:13 - Oral vs Injectable Testosterone: Benefits and Comparisons

01:05:55 - Kyzatrex: A New Approach to Testosterone Delivery





If your goal is to minimize chances of driving up hematocrit let alone hitting a high-end short-lived daily peak twice daily then 400 mg BID is most likely the way to achieve such unless you are one of those hyper responders who will fare well on a lower daily dose!



*At a mean follow up time of 6 months, patients demonstrated a significant increase in TT (263 to 798 ng/dL), drop in SHBG (32.4 to 17.83 nmol/L), and increase in calculated fT (7.24 to 26.74 ng/dL). FSH and LH, while lower, were maintained at non-zero levels (FSH from 5.7 to 2.9 mIU/mL and LH from 3.3 to 1.9 mIU/mL). Estradiol modestly increased (20.5 to 24.7 pg/mL) while hematocrit did not significantly increase (44.9% to 47.4%). No patients reported testicular atrophy or were initiated on aromatase inhibitors. One patient had a hematocrit rise above 52% (53.2%) and was reduced to 300 mg BID.

* Initiating oral TU therapy with Kyzatrex at 400 mg BID is safe and effective in achieving therapeutic serum testosterone levels. The high dose was well-tolerated and resulted in substantial symptom improvement, high patient satisfaction, and adherence. These findings support considering a higher starting dose for hypogonadal men considering oral TU therapy.





 
Big pharma transdermal T patch Androderm manufactured by Allergan Inc. was discontinued back in 2018!

Big pharma brand name Andriol (oral TU) manufactured by Merck was also discontinued back in 2018 and more recently 2024 our beloved Delatestryl (testosterone enanthate) manufactured by Valeant has been discontinued.

The only oral TU available is the generic PMS-Testosterone and Taro-Testosterone capsules.

Come 2025 we may have the option to use the newer versions of oral TU Kyzatrex or Tlando which are available in the US as Marius Pharmaceuticals and Verity Pharmaceuticals are currently seeking approval from Health Canada!

The only injectable TE available is the recently approved generic Hikma testosterone enanthate although it looks as though there is going to be an ongoing shortage in the market!

For injectable TC we still have big pharma Depo-Testosterone manufactured by Pfizer or generic Taro-Testosterone Cypionate.

Main downfall here is they are both only available in the 100 mg/mL strength!

When it comes to transdermal T we still have big pharma Androgel manufactured by BGP Pharma ULC and the generic Taro-Testosterone gel or brand Testim gel manufactured by Paladin Labs Inc.

Downfall here is the strengths are low compared to compounded transdermal gels/creams.

Luckily we still have the option of seeking out compounded transdermal or injectable T.

We also still have nasal T gel Natesto manufactured by Acerus Biopharma Inc but they are on shaky ground!

Sorry bros but the short-acting injectable TP (testosterone propionate) will never be available so your only option would be seeking out a UGL source!




View attachment 48145








The generic PMS-Testosterone now discountinued due to business reasons.

The only option left for oral TU is the Taro-Testosterone capsules.

No big deal here as the majority of men are using injectable esterified T (enanthtae/cypionate).

Hopefully Health Canada approves Kyzatrex which should happen sometime soon if it goes through!

It is doing well in the US as Marius is taking the game over for oral T-therapy!

Their team is stacked and the relentless marketing is making a huge difference.




1749407952322.webp

1749407980481.webp
 
The generic PMS-Testosterone now discountinued due to business reasons.

The only option left for oral TU is the Taro-Testosterone capsules.

No big deal here as the majority of men are using injectable esterified T (enanthtae/cypionate).

Hopefully Health Canada approves Kyzatrex which should happen sometime soon if it goes through!

It is doing well in the US as Marius is taking the game over for oral T-therapy!

Their team is stacked and the relentless marketing is making a huge difference.




View attachment 52057
View attachment 52058

 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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