Nelson Vergel

Nelson Vergel

Nelson Vergel

A New Frontier in Diagnosing Low Testosterone: The CAG Repeat Game-Changer
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Imagine going to your doctor, complaining of fatigue, low libido, and mood swings, only to be told your testosterone levels are "normal." Frustrating, right? Well, a groundbreaking study from the University of Sheffield and Barnsley Hospital...
Weight Loss Could Be Key to Male Infertility: What the Research Says
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Weight Loss Could Be Key to Male Infertility: What the Research Says There's some exciting news for men struggling with infertility and obesity—losing weight could make a big difference. For the first time, research shows that shedding extra...
A Review on Testosterone: Estradiol Ratio—Does It Matter, How Do You Measure It, and Can You Optimize It?
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There is a natural balance between the major sex steroids, testosterone and estradiol, controlled by gonadal secretion and peripheral conversion by aromatase. This balance is impacted by a variety of inborn and acquired conditions, and, more...
Enclomiphene versus clomiphene study results
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Among 66 patients, enclomiphene exhibited a median testosterone increase of 166 (vs. 98 ng/dL, P=0.20) with lower estradiol change than clomiphene (–5.92 vs. 17.50 pg/mL, P=0.001). Adverse effects were statistically significantly less frequent...
Heavier Men May Require Higher TRT Doses
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We finally have a study that looked at this common question. Effect of Weight on Serum Testosterone Levels with Subcutaneous Testosterone Enanthate in Men with Testosterone Deficiency Introduction Obesity is a common issue among men and is...
Responses of different doses of testosterone injections on body composition, strength, etc.
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Comment: 125 mg per week was the lowest dose that provided statistically significant changes in lean body mass and fat mass. PAPER ATTACHED Testosterone dose-response relationships in healthy young men. Bhasin S, et al. Am J Physiol...
Semen Analysis Optimum Parameters
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Here is a sample semen analysis report (optimum ranges) that I was able to obtain from a friend. Infertility testing: In an evaluation of a man's fertility, each aspect of the semen analysis is considered, as well as the findings as a whole...
Testosterone Decreases Fat and Increases Muscle: Study Explores Mechanism of Action
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PRDM16 is a gene that helps control the development of two types of fat in the body: brown and white fat. Brown fat helps generate heat and burns energy, while white fat stores energy. PRDM16 plays a key role in determining whether cells become...
500 IU of hCG Twice Per Week Used Alone in Men with Low Testosterone and ED- Study Results
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The study titled "Efficacy of 500 IU HP-hCG in the Management of Testosterone Deficient Secondary Male Hypogonadism," conducted by researchers at Chirayu Medical College and Hospital in Bhopal, Madhya Pradesh, aimed to evaluate the effectiveness...
Interview with Compounding Product Expert Shaun Noorian from Empower Pharmacy
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Nelson Vergel: I'm very happy to have Shaun Noorian, the owner and manager of Empower Pharmacy in Houston. He's a member of ExcelMale.com, and answers a lot of questions there. He's also a member of our ******** group called Testosterone...
Prostate cancer genotyping for risk stratification and precision treatment
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Understanding Prostate Cancer Genotyping and Risk Stratification Prostate cancer is a serious condition that affects many men, especially as they get older. Scientists are constantly looking for better ways to understand who is most at risk and...
Association of serum uric acid with male sexual hormones and erectile dysfunction
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This study investigates the causal relationship between uric acid test values and male sexual hormones, including testosterone, sex hormone-binding globulin (SHBG), estradiol (E2), and erectile dysfunction (ED) using a bidirectional two-sample...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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