Questions new protocl

I am injecting 0.4 ml twice a week from a cyp/prop 160/40 mg/ml twice a week. This is 80mg twice a week if I am doing my calculations correctly. It fact my total T was a lot higher and my T was in the mid 20s when I started with Defy. My total T has come down to the number quoted above and my SHBG has also come down from 77 to 62. I assume this is what is causing my free T to be where it is at. In fact, the Defy doctor told me in my last consultation that we should not even pay attention to the high T ( due to my high SHBG) and focus on free T. Not sure what I am missing. Thanks.
How is your HCT running, any issues with high levels?
 
Yes, that is the way I felt. I miss that!

We are all focused on hormones, but perhaps it's something to do with neurotransmitters?

Dopamine, which controls pleasure, reward and anxiety .

Epinephrine, which is involved in the fight or flight response. Epinephrine is what makes lovers' hands sweat, causes hyperactivity and your hearts racing.

Serotonin, which is associated with mood, sexual desire, appetite, sleep, memory and learning.

Main reason I mention this, if it were all hormonal, I would think we would have discovered the magic combination by now.
 
How is your HCT running, any issues with high levels?
No issues with HCT or nay other marker. I run a complete blood panel with my functional medicine doctor. 17 pages! Everything is good. What puzzle me is how quickly the change happened. 4 weeks of feeling like 20 again and then all the sudden this change. I can and do get erections but not as strong and as often as those 4 weeks. I do get my morning wood but I used to get it before starting hormone replacement therapy. Anyway, I will find out what it is. I have an appointment tomorrow with Defy but also seeing an amazing functional medicine doctor.
 
We are all focused on hormones, but perhaps it's something to do with neurotransmitters?

Dopamine, which controls pleasure, reward and anxiety .

Epinephrine, which is involved in the fight or flight response. Epinephrine is what makes lovers' hands sweat, causes hyperactivity and your hearts racing.

Serotonin, which is associated with mood, sexual desire, appetite, sleep, memory and learning.

Main reason I mention this, if it were all hormonal, I would think we would have discovered the magic combination by now.
Humm.. Maybe you are right. I will look into this. Thank you
 
Humm.. Maybe you are right. I will look into this. Thank you
Yes. I checked one of the many tests that I have done in the last moth. Great input, thanks! I run an organic acids tests and I do have some some Neurotransmitter imbalances. I don't remember what my doc said about it but I will ask her tomorrow. Good point. Just curious, have you tested for that? If so what do you take? Thanks!
 
Yes. I checked one of the many tests that I have done in the last moth. Great input, thanks! I run an organic acids tests and I do have some some Neurotransmitter imbalances. I don't remember what my doc said about it but I will ask her tomorrow. Good point. Just curious, have you tested for that? If so what do you take? Thanks!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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