Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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When I considered the tri-amino the thing I found disagreeable (personal pref) is that I didn't want to inject 1ml or more subq...that's a lot of fluid. Just a personal thing. Read Defy's page on how to use it.
 
Yes, I have used it many times. Injections for amino acid bio-availability is the best as the stomach and the first pass effect always play a toll on injestables.

You want to do the injections just before bed to get the bump in endogenous GH when you sleep and one hour before your work out to get a sick pump and massive vascularity.

It's good stuff and I like it.
Many thanks Gene! Your input is always appreciated!
 
When I considered the tri-amino the thing I found disagreeable (personal pref) is that I didn't want to inject 1ml or more subq...that's a lot of fluid. Just a personal thing. Read Defy's page on how to use it.


I used a shallow IM injection with a pin and never had a problem.

You could even go SQ if you wanted into any fat pad and still get excellent results.

I know, 1 ml sounds like a lot but it's not a problem at all.

If you're really interested in the tri-amino I say give it a shot!
 
Gene,

Since we are on the 27th page of this thread and I know from following it you have changed the stack as you have found better ingredients, can you post either in this thread or a new one what you are currently using as the stack and if you have the time where you are getting the ingredients.

Tom

Thank you Tom - I was thinking the same thing!
 
Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)



Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)




Most Important Testosterone, HCG, Anastrozole, Trimix, etc Fact Sheets on ExcelMale

I want to start this so bad!!!!! I have everything except what requires a prescription and I will inquire on that when I do my Defy consult... Should I start everything else without those 2 things? I need that forearm!!!!
 
You don't "need" half the things in that stack, sure they're nice and work in conjunction with each other, last thing I'd worry about is the Doxazosin. Which you can get from the online pharms w/o a script. Main two ingredients and the bulk of the success is the Arg and Citrulline.
 
New here. Just starting to get things ordered. Securetabs is having issues taking a VISA cc payment from new customers and doesn't know when they will get it fixed. Does anyone know of other legit sources to get Tadalafil in pill format?

Thanks!
 
I think ADC and reliable are the same company or both have the same web developer. Neither are taking credit cards at the moment so I am waiting until they get it working again. I never needed a script before, but noticed it mentioned when trying to check out.
 
My 2 cents - Get all the other ingredients and start taking it. As Vince mentioned, you are getting a ton of N.O. from the Arganine and Citruline.
 
My 2 cents - Get all the other ingredients and start taking it. As Vince mentioned, you are getting a ton of N.O. from the Arganine and Citruline.

I started today (minus the prescription stuff, add in Beet Root).... I can't wait to see how this goes... I have a pretty think bone structure and thick/bulky build so I would love some cuts and vascularity...
 
I almost have everything myself. Probably a good idea to ramp up anyway, and not take it all at once for the first time.

Don't forget to use a prepaid credit card for the overseas purchases.
 
You don't "need" half the things in that stack, sure they're nice and work in conjunction with each other, last thing I'd worry about is the Doxazosin. Which you can get from the online pharms w/o a script. Main two ingredients and the bulk of the success is the Arg and Citrulline.

Some of us don't even bother with Arginine except if you want to take it pre-workout. I take a higher dose of Citrulline to make up for it. Vince or someone posted some links about Arginine not being as efficiently processed whereas the citrulline goes right to the kidney.

In any case I don't see where it hurts to take L-Arginine I just chose to use BeetRoot powder once a day instead and now take 3g of L-Citrulline. I have a big sack of L-Arginine power so I tend to take some pre-workout when it's handy.
 
Thank you Vince, but I don't have a script for it so I'm looking for something like SecureTabs that doesn't require one.

I just click right on past that prompt for a script and I always get my product. That script request may be there for other purposes but it's not a "required" entry that I've had my order rejected.
 
I've been on Gene's stack minus the Cialis(made my lower back ache) and the doxazosin and it worked great, added beetroot powder and worked even better. this routine is hard to stick to unless you have plenty of disposable income and free time to take this much stuff 3 times a day. a recent study by the journal of the international society of sports nutrition showed taking L-citrulline and glutathione significantly increased markers of NO production, most notable 30min after working out, NO production decreased in the placebo group. This was 2grams of L-citrulline and 200mg of glutathione daily. This is a great stack Gene has put together but for those who need to it can be modified to fit your pocketbook and be effective.
 
Has anyone had any issues with gout flare up on this stack? I have had gout in the past and I know that Arginine can raise uric acid levels and cause a gout attack. I haven't had an attack in a while and no longer need my daily allopurino; I was up to 300mg a a day at one point. I lost close about 40 pounds and that seemed to really help the uric acid levels...Would love the benefits described, but would not want to deal with the gout again.
 

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