Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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PDE5i's work like this in order of priority:

Strength:
#1. Lavitra
#2. Viagra
#3. Cialis

Half Life:
#1. Cialis - ~16 hours
#2. Lavitra - ~6 hours
#3. Viagra - ~4 hours

You want the longer half life for the stack so the drug is in effect for almost 24 hours.
 
Guys, is there a peticular reason why Doxosin is preferred over let's say alfluzosin?

Sorry I haven't read the whole thread yet. This is all new to me. The reason I ask is that I currently have a prescription for Alfuzosin, but I'm sure my Dr will let me try Doxosin.

Also can you consume Maca with this stack?

Also what if one wants to take a full 20mg of C on the weekend?
 
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Just completed reading the entire thread. Glad I did. A bunch of great info. Thinking about going bulk powders, and adding Beat powder. Powders are time consuming and a mess. The ability to use a spoon instead of a scale sure speeds things up.

Has there been any other updates to the stack?
 
I recently switched my L-Agrinine to a new product made by NutraKey.

It's a Aplha-Ketoglutarate which is both ultra micronized for higher bioavailability and also Pharmacy grade to boot.

I get it in the powder form and take it with my NO stack and believe it or I can see and feel a difference in both vascularity and harder muscle pumps.

Here's link to the product and I recommend the powder as you can add it to your protein shakes before and after each training session.

https://thenutrakey.com/product/arginine-akg/

This is an excellent product and not expensive as far as amino acid prices go.
 
I recently switched my L-Agrinine to a new product made by NutraKey.

It's a Aplha-Ketoglutarate which is both ultra micronized for higher bioavailability and also Pharmacy grade to boot.

I get it in the powder form and take it with my NO stack and believe it or I can see and feel a difference in both vascularity and harder muscle pumps.

Here's link to the product and I recommend the powder as you can add it to your protein shakes before and after each training session.

https://thenutrakey.com/product/arginine-akg/

This is an excellent product and not expensive as far as amino acid prices go.

Very cool! Thanks Gene! Appreciate your post.
 
I recently switched my L-Agrinine to a new product made by NutraKey.

It's a Aplha-Ketoglutarate which is both ultra micronized for higher bioavailability and also Pharmacy grade to boot.

I get it in the powder form and take it with my NO stack and believe it or I can see and feel a difference in both vascularity and harder muscle pumps.

Here's link to the product and I recommend the powder as you can add it to your protein shakes before and after each training session.

https://thenutrakey.com/product/arginine-akg/

This is an excellent product and not expensive as far as amino acid prices go.

What's a good starting dose?
 
Ive been using 5g Arg powder and mixing it with 2g Citrulline in a shaker bottle. The flavor is barely tolerable, it's not terrible but it's not great. I still capsule and tablet the Doxazosin and Pycnogenlol, use liquid Cialis.
This last week after stopping Omeprazole which competes for NO or donwregulates NO, I'm having superb erections. Reliable erections. I'm quite pleased. I used the stack twice per day and mid day I get a heavy dose of Citrulline in my preworkout so I count that, too.
 
Ive been using 5g Arg powder and mixing it with 2g Citrulline in a shaker bottle. The flavor is barely tolerable, it's not terrible but it's not great. I still capsule and tablet the Doxazosin and Pycnogenlol, use liquid Cialis.
This last week after stopping Omeprazole which competes for NO or donwregulates NO, I'm having superb erections. Reliable erections. I'm quite pleased. I used the stack twice per day and mid day I get a heavy dose of Citrulline in my preworkout so I count that, too.

Good to hear Vince. Sounds Luke you figured out a good econo route for this stack. Is the liquid C working for you? Does it compare with brand name?

Are you buying pycnogenol in bulk powder?
 
The liquid I get as a "research chemical" works as intended, I can't compare to brand name, insurance won't pay for it and it's too pricey otherwise.
This is the same thing as Pyc, "French Maritime Pine Bark Extract, or pinus maritima" and quite economical.
http://www.amazon.com/gp/product/B00FFAFUAU?psc=1&redirect=true&ref_=oh_aui_detailpage_o03_s00

Great thanks! Be nice too do a poll on Indian pharmacy compared to research chems compared to name brand.
 
I just use the scoop they provide which is about 1.5 grams.

I use it three times a day and bookend my training sessions with in added into my protein shake.

Cool...thanks. I ordered everything last night. I'll probably start out slow and check blood pressure as I increase dosage.
 
Great thanks! Be nice too do a poll on Indian pharmacy compared to research chems compared to name brand.

I've done both and found Research Peptide Sites to be an excellent quality, easy to order, easy to get, no custom concerns and best of all...it works.

Just give it a try and you'll see.
 
Thing I found to split the research chems are how they're formulated, I guess, I like a more watery consistency over a thicker more viscous formula. Personal preference.
 
It's an Alpha blocker though I have no idea with Alpha's with different names act in the same way. If you're having trouble finding it I might suggest you give the stack a try without it as you may not need it. Doxazosin(?) is easily found at the usual overseas pharmacy's, look for "Doxacard".
 

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