Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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I worked shoulders yesterday and my pump was extreme to say the least.... And I haven't even started the Cialis yet!!! Can't wait to add that and see what happens...

Awesome! I'm sitting on the couch thinking about going to the gym. If not today then tomorrow. Just got back from Vegas. Still recouping.
 
Awesome! I'm sitting on the couch thinking about going to the gym. If not today then tomorrow. Just got back from Vegas. Still recouping.

Also I have some vascularity but not much... I have also not eaten so great over the holidays and it's cold... With all that being said I could see veins in my biceps (wasn't even working them) yesterday that I have never seen before! When I lean up a %, add Cialis and it gets warmer I can't wait to see the results!!!! Also I am in-between doctors so My T is falling yet I still have morning wood!!!!
 
WOW! that's great! I'm also in the process of switching over to Defy. Currently on cream and it's working, but want to start HCG and current doc won't.

I felt best on cream but I was concerned about too much DHT in regards to my hair loss... From what I am reading I think Cream/gel, HCG along with back filling some other hormones might be the best route... Sermorelin has me intrigued but I wonder if labs dictate it's use or finances...

Add this ^^^^ to Gene's stack and I think I/we will be rocking....
 
I felt best on cream but I was concerned about too much DHT in regards to my hair loss... From what I am reading I think Cream/gel, HCG along with back filling some other hormones might be the best route... Sermorelin has me intrigued but I wonder if labs dictate it's use or finances...

Add this ^^^^ to Gene's stack and I think I/we will be rocking....

Sermorelin runs a few hundred dollars a month and takes 6 months to a year to see results - just an FYI - not trying to talk you out of it.
 
Sermorelin runs a few hundred dollars a month and takes 6 months to a year to see results - just an FYI - not trying to talk you out of it.

I don't think I took any labs in regards to it... I keep seeing how people sleep better and I have never been a good sleeper, that intrigues me the most... I just wonder if they would introduce to the protocol regardless of labs...
 
2 Protocols:

Daytime (Nitric Oxide Protocol)
The Nitric Oxide protocol is comprised of ingesting 6 grams, which is 6,000 milligrams of specifically formulated arginine, 1-3 times during the day.


Benefits following the Daytime Protocol:
Anti-oxidant
Is Rejuvenative
Is an Adaptogen
Boosts energy level
Helps maintain healthy blood sugar levels
Reduces blood pressure
Reduces risk of heart disease, stroke and cholesterol
Unclogs arteries
Reduces the risk of cardio-vascular heart disease
Improves cardio-vascular disease that is already prevalent
Helps in promoting healthy Sexual Performance
Directions for taking L'arginine for Daytime Use: (General Health Benefits)
Suggested Serving: Mix one serving (3/4 scoop providing 3 g L-arginine) with 4-8 oz. water (depending on individual taste). Stir to dissolve. If water is very cold, mixture will take about 1 minute to dissolve. Add 3-4 cubes of ice to activate the flavour system (if desired). One serving (1 scoop) may be taken one to three times per day. Do not take within ½ hour of other meals or drinks. Do not mix with high glycemic drinks, flavoured water, or juices.


2. Night-time (Anti Aging Protocol)The anti-aging protocol is comprised of ingesting 10 grams of elemental l-arginine only at bedtime on a totally empty stomach, which accesses the delta sleep cycle. If you take l-arginine during the night you will get all of the benefits of Nitric Oxide and anti-aging. If you take l-arginine during the day you won’t get any anti-aging benefits. It really just depends on what people are looking for.Benefits following the Night-time Protocol:
Increases Muscle Mass

Supports Growth
Stimulates Muscle Development
Supports Hypothalamic Response
Helps decrease Body Fat
Anti-oxidant properties
Helps maintain Healthy Blood Sugar Levels
Boosts energy levels
Is Rejuvenative
Helps in promoting Healthy Sexual Performance
Is an Adaptogen
Growth Hormone: Helps provide necessary building blocks for the body to maintain healthy growth hormone levels
Helps produce Nitric Oxide
Stimulates production of Human Anti-Aging mechanisms for those over 23 years.
Directions for taking Larginine for Night-time Use: (Anti-Aging Benefits)
Anti-aging benefits of L-arginine only occurs when 6-10 grams of specifically formulated L-arginine is ingested in a low glycemic format with no competing proteins or amino acids present.

Mix 2 servings (2 full scoops) in desired amount of water, 30 minutes prior to sleep on an empty stomach. Do not ingest food, including protein drinks, high glycemic drinks, or supplements containing any other amino acids with or within 2 hours of taking this product at bedtime. Ingesting food, amino acids, or high glycemic ingredients with or near this product is not in any way harmful, it simply will negate the benefits.
L-Arginine will not work unless you follow this protocol. If you don't go to sleep within that time frame or if there is a presence of food, the L-arginine will not cross the blood brain-barrier. The L-Arginine benefits for the night-time protocol will be wasted. You need to sleep for a minimum of 4 hours. Ideally you should sleep 8 hours for your body to repair itself.

You will still get the Cardio-vascular benefits, but not the anti-aging benefits.

Obviously you need to decide which is best for your goals.

Source of Data: Arginine Dosage
Also there is a few other sites that support these assumptions you can find several by simply googling key words.
 
Thanks Vince, think I've read you are supposed to take on an empty stomach. Just wondered how important it was. I'll do some searching.
 
Hey guys how does Gene get a 12 hour split for the Cialis and Doxazosin if you take it in the afternoon and before bed. That's more like 8-10hours?
 
Gene, do you take this everyday? If yes, do you plan to take it for life? I am 55. Erections taking much longer to achieve and not as good as they used to be. During sex, instead of a continuous erection - it waxes and wanes. This has me very worried.
 
Gene, do you take this everyday? If yes, do you plan to take it for life? I am 55. Erections taking much longer to achieve and not as good as they used to be. During sex, instead of a continuous erection - it waxes and wanes. This has me very worried.

It says morning, noon, and bedtime so yes, it's a 3x a day regimen, and for life? Yes, if you want the benefits of it you must take it daily.
 
Gene, do you take this everyday? If yes, do you plan to take it for life? I am 55. Erections taking much longer to achieve and not as good as they used to be. During sex, instead of a continuous erection - it waxes and wanes. This has me very worried.

Yes, I take this every day and plan on taking it for life; the health benefits abound.
 
Regarding icarin

I don't know of any stimulation effects of any amino acid and don't know how they could even do that knowing the way they work.

IMO, the body thrives on regulatory so there is no need to "cycle" off of the amino acids to get a better effect.

I've been on this for a number of years now and still get all the great subjective benefits.

This is an excellent health stack that can be taking for years.

All icarin that I am finding is minimum 500 mg. Your nitric oxide stack suggests 150 mg. Where can I find icarin in 150 mg dose? Thanks.
 
All icarin that I am finding is minimum 500 mg. Your nitric oxide stack suggests 150 mg. Where can I find icarin in 150 mg dose? Thanks.

Check the %... Mine is 30% so that would make it 150MG... I love the stack as much as anything in my protocol... For me the Pycnogenol is what I seem to run out of the most and is the most expensive...
 

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