Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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My family practice doc prescribed it based on a past of having prostatitis a couple of times. I mean I had to ask. He didn't think it was strong enough to replace Lisinopril (and it wasn't) but figured the drug was good for "men's stuff".

He also prescribes Test and typically around 200mg per week is what most guys are on, but I didn't ask him to do it since I'd have to pay for it anyway because even though it's in our plan, they can deny it if you are over the low end of the range. So I stuck with Defy. Plus I am not sure if he prescribes HCG.
 
It's an Alpha blocker though I have no idea with Alpha's with different names act in the same way. If you're having trouble finding it I might suggest you give the stack a try without it as you may not need it. Doxazosin(?) is easily found at the usual overseas pharmacy's, look for "Doxacard".

Having taken "Doxacard", I can attest to the fact that it does, indeed, work as expected.
 
My family practice doc prescribed it based on a past of having prostatitis a couple of times. I mean I had to ask. He didn't think it was strong enough to replace Lisinopril (and it wasn't) but figured the drug was good for "men's stuff".

He also prescribes Test and typically around 200mg per week is what most guys are on, but I didn't ask him to do it since I'd have to pay for it anyway because even though it's in our plan, they can deny it if you are over the low end of the range. So I stuck with Defy. Plus I am not sure if he prescribes HCG.

Thinking about going with Defy myself. Meeting with my Doc today to discuss HCG, but I bet I'll probably be his first patient to take it.
 
Having taken "Doxacard", I can attest to the fact that it does, indeed, work as expected.

Good to know thanks. I couldn't find anything searching Doxicard, but I did find generic Doxazosin. Meeting with my urologist on Monday to discuss Doxazosin, but in an email he's already said it has too many side effects and prefers Alfuzosin.
 
Good to know thanks. I couldn't find anything searching Doxicard, but I did find generic Doxazosin. Meeting with my urologist on Monday to discuss Doxazosin, but in an email he's already said it has too many side effects and prefers Alfuzosin.


At the dose in my stack for Doxazosin the sides are rare...this is a very very low dose compared to how its prescribed by label.
 
Gene, just wanted you to know I've been following your protocol for the past few months and have had really great success. I read your recent post regarding arginine -akg and to be honest, I was a bit skeptical about whether I would really be able to feel a difference, but your advice has been so spot on in the past, I gave it a whirl. Much to my surprise, I did feel a difference. Not huge, but definitely noticeable. I guess the best way to describe it is my erections, while great already, were of an even higher, er, shall we say, quality. Thanks again for sharing - good stuff!
 
Gene, just wanted you to know I've been following your protocol for the past few months and have had really great success. I read your recent post regarding arginine -akg and to be honest, I was a bit skeptical about whether I would really be able to feel a difference, but your advice has been so spot on in the past, I gave it a whirl. Much to my surprise, I did feel a difference. Not huge, but definitely noticeable. I guess the best way to describe it is my erections, while great already, were of an even higher, er, shall we say, quality. Thanks again for sharing - good stuff!


Yes, the akg is a better quality L-Arginine product. Amino's are difficult to get good bio-availability due to the digestion process and Firs Pass effect. Whenever a product is "super micornized" bio-availability is significantly increased. Add to that the Pharmacy Grade and you know the product has to to live up to the standards of what it says it is...in other words, top quality.

All of this goes to better uptake and getting the end results we are seeking...it's why I use it now as part of my stack and to your point, I too have noticed a difference as well.
 
Gene,

Since we are on the 27th page of this thread and I know from following it you have changed the stack as you have found better ingredients, can you post either in this thread or a new one what you are currently using as the stack and if you have the time where you are getting the ingredients.

Tom
 
Hey guys on the icariin that Gene recommends it's 300mg per capsule. Gene's stack says 150 per serving. Is that being split in half or what? I think this was discussed in the thread, but didn't want to read 27 pages again.
 
Beet Root is just another way to get nitric oxide than taking Arginine and/or Citrulline. Adding it though would probably just be overkill and unnecessary. I tried some beet root powder and mixed with water it was terrible, I won't use it again.
 
Beet Root is just another way to get nitric oxide than taking Arginine and/or Citrulline. Adding it though would probably just be overkill and unnecessary. I tried some beet root powder and mixed with water it was terrible, I won't use it again.

I take Nature's Way 500MG capsules of beet root... I am naturally bulky and have a big bone structure (8 inch wrist @5 10.5) so I would love to get some cuts and vascularity... I can't wait to try this...
 
I take Nature's Way 500MG capsules of beet root... I am naturally bulky and have a big bone structure (8 inch wrist @5 10.5) so I would love to get some cuts and vascularity... I can't wait to try this...


That's the one I use as well.

This is a "stack" with the strategic idea that synergistically each compound works with one another to get optimal results...just like any stack.

You can see from the responses in here from the men who use it in some form that it provides for some amazing results!
 
Hi Gene, have you or anyone on this thread tried Defy Medical's tri-amino? I am wondering if it would be a stronger or more effective way to take advantage of the benefits of Arginine/Citrulline...
 
That's the one I use as well.

This is a "stack" with the strategic idea that synergistically each compound works with one another to get optimal results...just like any stack.

You can see from the responses in here from the men who use it in some form that it provides for some amazing results!

I will be a virgin for everything on the stack... So I am very excited to start... I am about 225-230 at 15% body fat... I need to cut a few percent but that forearm pic is amazing!!! I want just a slice of that vascularity!!! And morning wood would be nice too....
 
Hi Gene, have you or anyone on this thread tried Defy Medical's tri-amino? I am wondering if it would be a stronger or more effective way to take advantage of the benefits of Arginine/Citrulline...


Yes, I have used it many times. Injections for amino acid bio-availability is the best as the stomach and the first pass effect always play a toll on injestables.

You want to do the injections just before bed to get the bump in endogenous GH when you sleep and one hour before your work out to get a sick pump and massive vascularity.

It's good stuff and I like it.
 
I will be a virgin for everything on the stack... So I am very excited to start... I am about 225-230 at 15% body fat... I need to cut a few percent but that forearm pic is amazing!!! I want just a slice of that vascularity!!! And morning wood would be nice too....


You will get both...

I have buds in the gym tell me that when I an on my last reps per set and really straining that veins are popping out all over the place LOL!
 
You will get both...

I have buds in the gym tell me that when I an on my last reps per set and really straining that veins are popping out all over the place LOL!

Morning wood just stopped a couple weeks ago for no reason... My guess is E2 creeping on me... Just not the same waking up without it!!! Vascularity is a very nice touch and I have a little but not near enough... I can't wait to start it... It really just makes you look so more athletic...
 

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