Empower’s 200mg/ml T cream is equivalent to what injection dosage?

[Caketocake]

Sorry for the newbie question but can someone tell me with Empower’s 200mg/ml cream doing 2 clicks twice per day (scrotal application) is equivalent to how much of the same injection dosage?

 

[Cataceous]

Because of wide variations in absorption you're not really going to know until you try it. But I can give you a sense of the numbers. I assume your dispenser is giving a quarter of an mL per click, so you're talking about 200 mg per day. Through regular skin, absorption can be around 10%, or 20 mg. This is like 28.56 mg of testosterone cypionate per day, or 200 mg per week. However, scrotal skin can absorb much more efficiently, with cited figures going up to 60%. With this amount you'd be getting 120 mg per day of T, equivalent to 172 mg T cypionate a day or 1200 (!) mg per week. I kind of doubt you'll see this much absorption, but it still seems like a high dose, and one likely to send DHT extremely high.

 

[Cataceous]

I should add that the figures I mentioned are for gels. Creams might not be absorbed quite as well, making the numbers a little less outlandish.

 

[Vince Carter]

Cataceous gave a great breaksdown there but you really can't equate the two, you'd have to get started on a dose and test and evaluate and titrate up, or down.

 

[S1W]

Having done both 100mg (1/2 ml 200mg/ml cream/day) compounded cream and 100mg/week (50mg E3.5D) injections they were likely somewhat similar for me.

Anyway, Vince Carter is correct in that you cannot equate creams/injections.

EDITED: To remove part where I questioned dosing - I did not read the original post closely enough.

 

[Cataceous]

Cataceous knows his stuff and I'm sure either he made a typo or I'm not reading it correctly, but if it is 200mg/ml, and you're using 2 clicks per day, wouldn't that be 1/2 ml = 100mg? That would be closer to 100mg/week injections, not 200mg/week.
...

Caketocake said "2 clicks twice per day".

 

[S1W]

Caketocake said "2 clicks twice per day".

Ha! I guess it was problem #2 on my part - I didn't read it correctly.

 

[Cataceous]

Ha! I guess it was problem #2 on my part - I didn't read it correctly.

I made the same mistake—something about having two "twos" in the sentence?—but I caught it while still writing my post...

 

[SteveCleves]

Did some forum searching and online research on this topic. This seems to be the most relevant.

It seems like, in practice, the scrotal cream to injected equivalent, again in practice, is that your daily cream dose is roughly equivalent to a weekly dose of injectable test.

So 200mg of 20% cream on scrotum daily is roughly equal to 200mg of test cyp weekly.

Thoughts?