Is storing extra Testosterone Cream 20% 200mg/ml in Freezer safe to do?

Caketocake

New Member
Well, I was prescribed the 200mg/ml T Cream (transcrotal) two clicks, twice a day, however after receiving 3 bottles of it, I have been only doing it at one single click, once a day with surprisingly VERY good results. At this rate (if I maintain the same dosage), these bottles will end up lasting quite a while. The bottle says discard after 6 months. If I store them in the freezer, will they be able to go past the 'use by/discard by' date?
 
It's a pretty good bet that out of caution they will recommend against freezing. The procedure is unlikely to have been tested, and there will be concerns about crystallization and separation of ingredients. The expiration date at six months out typically means that it's only been tested for that long, not that the medication suddenly goes bad after that.
 
Well, I was prescribed the 200mg/ml T Cream (transcrotal) two clicks, twice a day, however after receiving 3 bottles of it, I have been only doing it at one single click, once a day with surprisingly VERY good results. At this rate (if I maintain the same dosage), these bottles will end up lasting quite a while. The bottle says discard after 6 months. If I store them in the freezer, will they be able to go past the 'use by/discard by' date?

No pharmacy will ever recommend using past the discard date regardless of whether it works or not.

I wouldn't freeze it myself, I would seal it in a couple of plastic zipper bags because it seems like the cream tends to dry out.

I never like freezing any sort of creamy substance.

Try bagging it, use the oldest one you have, then do a total T test to see if it works any different.
 
It is not recommended to store the cream at a temperature other than what is indicated on the medication. Stability studies that have been performed using the active ingredient, Testosterone, and the vehicle that the Testosterone is mixed in shows almost no degradation after 180 days , so the potency of the medication likely won't be significantly affected if used for a short period of time after the Beyond Use Date stated on the medication
 
Well, I was prescribed the 200mg/ml T Cream (transcrotal) two clicks, twice a day, however after receiving 3 bottles of it, I have been only doing it at one single click, once a day with surprisingly VERY good results. At this rate (if I maintain the same dosage), these bottles will end up lasting quite a while. The bottle says discard after 6 months. If I store them in the freezer, will they be able to go past the 'use by/discard by' date?
Newbie here,
I store meds in the fridge “ cool and dry”.
 
I live in a part of the country that gets very cold in the winter. I asked the local compounding pharmacy that made my cream about freezing, and the reply was that it would not affect the strength of the cream. Doing it intentionally and for long periods of time...that might change things?
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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