Blood work results, Defy initial consult coming up

JoseB

New Member
Long time lurker, first post. Just got back my lab results, waiting on consult with Defy. 44 year old male having trouble building muscle and toning. 5'6'', 155 lbs, skinny fat. Realized that DHT and Prolactin were not added to the blood test as requested, I do take finasteride 1mg EOD. What do you think?


Labcorp results:
Testosterone, Serum 821 ng/dL 264 - 916
Free Testosterone(Direct) 14.1 pg/mL 6.8 - 21.5
DHEA-Sulfate 341.8 ug/dL 102.6 – 416.3
TSH 1.45 uIU/mL . 0.450 - 4.500
LH 5.9 mIU/mL 1.7 - 8.6
Prostate Specific Ag, Serum 0.2 ng/mL 0.0 - 4.0
Insulin-Like Growth Factor I 153 ng/mL . 75 - 216
Estradiol, Sensitive 12.2 pg/mL 8.0 - 35.0
Sex Horm Binding Glob, Serum 54.8 nmol/L 16.5 – 55.9

Glucose 106 mg/dL 65-99 High
T4 1.8 ng/dL 0.82 -1.77 High
Reverse T3, Serum 21.4 ng/dL 9.2 – 24.1
T3 2.8 pg/mL 2.0 – 4.44
 
Free T isn't great but I doubt there's a real justification for TRT based on the numbers alone, most guys would like to have numbers like yours.
If anything get off the Finasteride...google "Post Finasteride Syndrome".
 
What concerns me is the estrogen at 12.2, free estrogen percentage and the fact SHBG is on the higher end. When I read the line about being on Finasteride, my heart skipped a beat. I would at the very least stop Finasteride and then if nothing improves consider TRT.

Finasteride can cause HPTA dysfunction so it's hard to recommend TRT at this point.
 
Thanks for both your replies. I've been on finasteride almost 15 years for hair loss, this year I decided to change to EOD because of some of the stories I've read on this forum. Thankfully, I have not had any of the sexual side effects. Let me read up on discontinuing use altogether.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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