1 year HRT and just started with injection - Troubleshooting

Low estradiol is something to avoid, just high estradiol is to be avoided. Frequently men at the commencement of TRT find themselves with low E2. As therapy progresses levels will typically rise. I would NEVER use testosterone undecanoate. It enters the body and levels jump, as can estradiol. Despite what you seem to believe, you will never get a steady-state level of testosterone with it because you are on a modified roller-coaster ride. Dr. Saya's response that I posted earlier states that in order to achieve true, steady-state serum levels it is necessary to inject very small amounts of testosterone on a daily basis. Most men do not need to do this, they achieve excellent results on every 3.5 day injections, or every other day injections. I went for a radical solution, so to speak, and am glad I did.
 
Low estradiol is something to avoid, just high estradiol is to be avoided. Frequently men at the commencement of TRT find themselves with low E2. As therapy progresses levels will typically rise. I would NEVER use testosterone undecanoate. It enters the body and levels jump, as can estradiol. Despite what you seem to believe, you will never get a steady-state level of testosterone with it because you are on a modified roller-coaster ride. Dr. Saya's response that I posted earlier states that in order to achieve true, steady-state serum levels it is necessary to inject very small amounts of testosterone on a daily basis. Most men do not need to do this, they achieve excellent results on every 3.5 day injections, or every other day injections. I went for a radical solution, so to speak, and am glad I did.

In the last few days a lot of my questions were answered. Thanks a lot for your answers.

Here a little update on my state/well beeing: Everyday it gets a little bit better. Tomorrow morning is Injection Nr. 4.
Anxiety is almost away and my head feels so much better than in the beginning. Tomorrow is gonna be the last E5D Injection. After that I will go down to E3.5D I think.
 
In the last few days a lot of my questions were answered. Thanks a lot for your answers.

Here a little update on my state/well beeing: Everyday it gets a little bit better. Tomorrow morning is Injection Nr. 4.
Anxiety is almost away and my head feels so much better than in the beginning. Tomorrow is gonna be the last E5D Injection. After that I will go down to E3.5D I think.

I am pleased to know you feel pleased. Keep,us posted!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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