trt

Hello, I have been lurking on this forum, looking at other cases and learning a little from them, but now I would like some guidance from you about my situation. At the age of 24, I was diagnosed with secondary hypogonadism, but it was a problem I had had before that age. (I related my symptoms...

My body has been wrecked since 2020. (got COVID19 June 2020, then hit by 2 hurricanes, August & October 2020). I am not sure if COVID was solely responsible for my current issues or the mix of two high stress environments caused me burn out to the point of adrenal failure which is what I believe...

Hi everyone, I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or only after HCG is discontinued. Here’s my full background and current plan: TRT History On TRT for ~3 years total Started...

Ive experienced and have seen others who have had trouble dialing in, that take days or a week of their protocol and feel so much better.. Ive felt this myself and cant figure it out. Its not as simple as the dose being to high, because I took some days off then adjusted my dose down 25% and the...

Hi everyone, I’ve been on TRT for about a year and I’ve tracked things pretty closely the whole time. I tried spreadsheets and a few tools, but nothing quite matched what I wanted, so I built this app for myself and I’m opening it up as a beta to share with the community. Axis estimates...

https://pubmed.ncbi.nlm.nih.gov/34445892/ Abstract Purpose: We sought to compare testosterone formulations and determine the degree that hematocrit increases vary by testosterone therapy formulation. As head-to-head trials are rare, network meta-analysis of the contemporary studies is the only...

Above is above is Most recent test at 28-30mg EOD. Below is test from end of July at 24-26mg EOD. Yes I feel like shit, and my shbg was 9.8! Im doing subq EOD and just recently am trying ED injections. I dont understand how my e2 has trippled? Does anyone have any input on this? What route...

I know I just started TRT at 140mg a dose with hcg. I'm never looking to go crazy then I need to and take more anabolic steroids. With under supervision, a lot of the risk can be mitigated? Even lets say I want to run TRT at least to change composition of how fat I look now to a bit fitted. From...

I've been on TRT for years, through the same clinic. I hadn't been taking my AI during that time, but the doc really, really felt that my numbers should be lower than 20, so he advised me to give it a try. Just did the blood work and yikes. T: 950 E: < 5 SHBG: 30 All of my other numbers are...

Hey guys, Looking for some advice on my TRT protocol. I'm 21, had testicular cancer last year (orchiectomy + chemo, now in remission). Been on TRT for about 3 months, trying to dial it in since I'm still having issues. Here's the situation: Complaint: Zero libido, some anhedonia, water...

I am 46 years old and I`ve been on TRT for around 7 years. I decided to try and stop TRT because It has been mostly ok but I struggle with libido and sensitivity down there as well as difficulty ejaculating and reaching orgasm although my testosterone was quite OK between always between 700 -...

Hi guys, Bit of context, I’m a 28-year-old male. I started TRT because of brain fog and wanting better muscle gains. When I first started Test Cypionate at 100 mg per week divided into 3 injections, I felt great for the first few weeks. But then I developed insomnia, bloating, and ED. I...

Hey guys….new here and just looking for some guidance. I’m a 51 year old male who I consider in pretty good shape. 5’9” and 180 lbs. I do CrossFit 3-4 days a week. I take no prescription medications. Only a couple of supplements. Very healthy with no risk factors for ED. Beginning of this year...

I have been taking 200mg of cypionate twice weekly for 12 weeks. I am "supposed" to be take 200mg bi-weekly. My doctor wants a blood test. How long after stopping the injections will my levels drop. Should I do PCT or just slowly go back to bi-weekly?

Hey all, I'm new here so I hope this question is ok as I've not found much on this low level of dosage. I've been dealing with high e2 symptoms for a while and my E2 is creeping up (currently 48pg/ml). Not super high but very high for me as I started trt at 15pg/ml. I just aromatize kinda...

Hello, I got 10% DHT cream in lipsomal base 50ml. How much of cream do I use per day? There is no instructions or dosing. Im using it for the purpose of PFS. Im on TRT cream as well. Thanks

Hello all. Im dealing with PFS symptoms from the use of finasteride. I went on TRT cream for symptom relief, but did not get much DHT related symptom relief. Looking to add DHT gel to my protocol. Anybody experienced benefits in regards to PFS symptoms with the use of DHT gel? Please advise...

Good morning all, Hope everyone is well. I am a 33 year old man, currently weighing 88kgs and height 1.83 cm (6 foot). I have been battling erectile dysfunction for 10 years or so, starting from when I was 22 or 23 years old. I have posted about my journey in this thread (Help with...

I've seen that some people measure their rate of aging using tools like genetic or epigenetic clocks (e.g., DNA methylation age). I'm wondering how different testosterone dosages, from standard TRT levels up to supraphysiological doses, might affect the speed of aging as measured by these...

Hello All, Long time lurker first time poster here. First of all thanks to all the people who make this great resource available. I have had many questions answered and the information here has helped me to better formulate the questions that remain. This is a long post with a lot to unpack so...

Just putting this out for discussion and comments. There have long been anecdotal suggestions that faster-acting testosterone leads to lower overall levels of estradiol. In particular, it's often claimed in regard to using testosterone propionate versus longer esters such as cypionate. It could...

After 5 years of HRT/TRT I'm packing it in. I now have BPH, I'm on a statin and repatha, I take cialis and an alpha blocker... testosterone and hcg, occasionally arimidex. The thing is that I didn't need any of these drugs 6 years ago before I started TRT so why am I on them now? I bought...

This guys channel is fascinating. N of 1 type experimentation with diet to see how blood markers correlate with increase or decrease of certain foods. He has great guests as well. This lecture explores immune resilience, a crucial factor for health and longevity that counteracts...

https://lpi.oregonstate.edu/sites/lpi.oregonstate.edu/files/2025-05/top_10_public_brochure.pdf Essential Micronutrients for Healthy Aging This briefing document summarizes key information from "top_nutrients for aging well.pdf," focusing on the importance of vitamins and minerals...

For those that have known me over the years know that in the past, I definitely had my struggles with TRT and I’ve tried pretty much everything there is to try. I have now been on TRT the better part of 16 years and for the last several years, I’ve been using 60 mg once per week of testosterone...

Hey all, I’ve been on topical TRT compounded cream (100 mg/day) for 52d now. No prior exogenous T before this. 50mg twice daily (AM/PM), rotating between behind knees, deltoids, and inner thighs. Chose to avoid transscrotal application as I didn't want to spike DHT/E2. I was on enclomiphene at...

Hello all. 36 years old. Just received my bloods today and as expected low levels all across the board. I had a test 3 years ago which also showed my testosterone levels at 10.9. I have had a few symptoms for the past few years but always just put it down to working shifts and getting older...

I’ve covered this issue in many posts, but I thought it would be helpful to put more information in one thread and expand on the topic. TL;DR: Under TRT, free testosterone is proportional to the dose rate and inversely proportional to the metabolic clearance rate. The liver accounts for most of...

I am now off all testosterone and these are my numbers. I felt better on 20mg a week. Not making sense to me. Curious if there's a way to fix the free and total imbalance. Any help or advice is appreciated

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Compound testosterone cream vs Subq injections? Which has less side effects and better results as I don’t want my rbc and hemo to shoot up blood pressure etc.