Always include the reference ranges/testing methods used for TT/FT and estradiol when posting labs.
Critical to use the most accurate testing methods TT/estradiol (LC-MS/MS) and FT (Equilibrium Dialysis).
You are getting caught up on your TT when the most critical fraction FT is what truly matters here as it is the active unbound fraction of T responsible for the positive effects.
The standard starting dose is 100 mg T/week or 50 mg split twice-weekly.
Yes some men may choose jump in on dailies but it's far from common.
You are injecting 100 mg T/week split into dailies and as you can see your hitting a very high TT 1130.6 ng/dL (39.2 nmol/L) but the s**t kicker here is you have really high SHBG 65.2 nmol/L which means your FT would be healthy but far from high.
Men with highish/high SHBG will need to hit a high-end/high TT in order to achieve a healthy/high FT.
Not sure what testing method was used for testing your FT but the only way to know where its truly sits would be testing using the gold standard Equilibrium Dialysis assay otherwise you would need to use/rely on the next best testing method the go to calculate Vermeulen (cFTV) which will give a good approximation.
If we use the go to cFTV with a very high TT 1130.6 ng/dL, high SHBG 65.2 nmol/L and Albumin 4.8 g/dL your cFTV 17 ng/dL is healthy but not high.
Top-end of the reference range 25 ng/dL.
View attachment 58139
View attachment 58138
FT <5 ng/dL would be considerd low.
FT 5-9 ng/dL would be considered the grey zone where some men may experience symptoms of low-T.
FT 10-15 ng/dL would be healthy.
FT 20-25 ng/dL would be high-end/high!
Your cFTV is 17 ng/dL and this is on a daily protocol!
Would not even consider lowering your dose yet as your FT is not that high and seeing as you are injecting daily your peak--->trough would be minimal and your blood levels will be very stable throughout the week.
If you were hitting a high FT 25-30 ng/dL then you would easily have room to lower your weekly dose and bring it down if. need be but this is not the case.
Highly doubtful your libido/ED issues have anything to do with your FT.
I would tread lightly when it comes to self treating with thyroid meds.
Even then chances are if your most recent prolactin 736 is high then it could easily put a damper on your libido and with a lack lustre libido that can cause ED.
Your prolactin 1243 back in may was even higher and you had a huge jump (285-1243) from 6-12 weeks of starting T.
Also keep in mind there is much more involved than just hormones when it comes to libido and erectile. function.
A Drop in Sexual Drive Among Both Men and Women in Middle Age Is Rarely Solely Due to Plummeting Hormone Levels; Clinicians Point to Erectile Dysfunction, Sleep Disruption, and the Overwhelming Influence of Relationship Quality and Mental Load. A notable decrease in sexual desire, or libido, is...
www.bocaratontribune.com
ED is multifactorial and vascular issues are the most common cause.
T plays a small role!
* only about 5% or less of erectile dysfunction is caused by hormone imbalances like a testosterone deficiency, surprisingly but its true because it has a smaller role with erections
* most erectile dysfunction is caused by vascular issues so vascular is the most common cause because many men have high blood pressure, cholesterol...
14:20-16:47 (erections/erectile dysfunction)
You need 5 things to get a good erection:
1. good blood flow
2. good nerves
3. good testosterone levels
4. neurotransmitters/arousal
5. state of mind
