The Use of Human Chorionic Gonadotropin and Testosterone in Adolescents with Constitutional Delay of Growth and Puberty and Hypogonadism

madman

Super Moderator
* This review integrates evidence across diagnostic, therapeutic, and psychosocial domains to clarify what is well supported, what remains provisional, and where the principal contradictions in the literature lie, and it proposes methodologically robust priorities for future research, including harmonized diagnostic thresholds, adequately powered comparative trials of gonadotropin regimens, and longitudinal assessment of fertility and bone outcomes into adulthood

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