shbg

From my many posts on this forum many people probably know by now that I am a Low SHBG guy (8-18 labcrop range) which manifested after starting TRT 10 yrs ago... I have never gotten dialed in despite numerous changes in Test dosage, injections, etc... It's been a struggle to lose weight despite...

Ok, I just read through the entire Low SHBG sticky thread and have been researching all over this forum regarding low SHBG and Trt dosing... I was able to pull a lab test from 12 years ago prior to starting TRT and I had a SHBG of 44 (lab corp range)... Since starting TRT my SHBG has dropped...

Sex hormone-binding globulin (SHBG) is produced and secreted by the liver into the bloodstream where it binds sex steroids and regulates their bioavailability. Traditionally, body mass index (BMI) was thought to be the major determinant of SHBG concentrations and hyperinsulinemia the main cause...

I've had an issue for the last couple of months now where my TT has not been nearly as high as it used to be given a particular dose of T cyp. Early Feb I saw a 600 off 150mg/week. Last week, 730 off of 182mg/week + 150IU HCG EOD. Last fall, I was at 1200 with 200mg/week. Where the hell could...

PARTICIPATION NEEDED! Of those EM members that have taken nandrolone or are currently taking nandrolone alongside their TRT, we are conducting a small ExcelMale study to help determine the effect that nandrolone has on Total Testosterone, E2, Prolactin, SHBG, free T, and DHT while taking TRT...

I know that most TRT places recommend 3-6 months for TRT to show results for low total T. My case may be different, as I have a test of 700 due to a high SHBG of 66. These were my baselines before starting Natesto. I’ve been on Natesto for 2 months, and I can’t really tell if it’s helping. I...

Gents, I’d love to get some input on this. I’ve started TRT 3 months ago. 43, fairly healthy, lifting 4 times a week. Baseline: BP 120/72 TT 275 (264-916) FT 12.5 (6.8-21.5) E2, SENSITIVE 10.6 (8-35) SHBG 25.7 (16.5-55.9) HCT 45.1 (37.5-51) TRIGLYCERIDES 117 (0-149) HDL 35 (39- ?) LDL...

I know there are many low SHBG posts and most are negative for the most part. I wanted to share some things that I have learned through some experimentation over the last 4 years seeking more libido that have helped me dial some things in to my current protocol: 19mg T-Proprionate ED .25mg AI...

Some threads state some folks "aromatize a lot" or "aromatize a little". What does this mean? Is it related to SHBG?

Hi everyone, I’m thinking of giving the scrotal cream a try after almost a year of injections and limited success with varying protocols. I’m wondering if there are any high shbg guys like myself that have tried the cream and what has been your experience? My shbg pre-trt was between 55-70. On...

I have been on TRT for 2.5 years and have had textbook levels - TT around 1000, FT in the 20's, SHBG fluctuates between 45-50 and E2 typically matches SHBG. I have never had any E2 symptoms though I will admit that my regimen would create an E2 nightmare for most - test cyp 60 mg every 3.5, HCG...

I haven't seen this mentioned previously. This suggests that those who are struggling with low SHBG should test for hyperinsulineamia. The relationship between serum levels of insulin and sex hormone-binding globulin in men: the effect of weight loss. As SHBG is not known to alter the...

Is there a proven way or supplement for lowering IGF1 ? Besides the internet BS regarding diet .

Hi, I have low SHBG, and have been on TRT for the past 5 years with very low success. If I feel good with energy and libido it is for a few hours/days, and then it fades. Since I have low SHBG, that was my first suspect, but after reading about post FPS and Accutane, I am afraid my issue is due...

Hi All, Can low SHBG guys comment on what is your protocol? and Whether it works successfully for libido and energy? - From what I have read and in my personal case, when E2 is low, mirroring SHBG values, it is like the sweet spot, and rationale is that the low SHBG makes too much of free E2...

Has anyone with low SHBG increased their injection frequency (say from 2x a week to every other day or daily) and found yourself feeling better?

Hi all, from the uk. 34 years old. starting TRT due to lifelong ED, and only weird thing in my bloodwork is over the range SHBG 60 ( 5-55 ) everything else is fine. I need caverject to perform, so I'm starting TRT to see if low free test is my issue. I injected 125mg on Sunday night few...

Just got approved TRT because of my tricky SHBG. Would love some advice on this subject.

I managed to cut my SHBG in half over 6 months by taking 9mg Boron Daily and an increase of 40mg of testosterone weekly. great free T increase as well!

Seems the standard protocol for TRT is to start at 100mg Test C per week. Should one consider a higher starting dose if they are: 1.) Larger (in my case 6'3", 200lbs, <10%bf) 2.) Have low total T of which a very high amount is SHBG My last test results are: Total test: 499 ng/dL SHBG: 55.1...

When I first started TRT may doctor at the time said that we needed to get my SHBG down as it was at 60. Sure enough TRT reduced it to 35. It crept up again as I was put on a lower T dose to try and reduce aromatisation ednding up at the start of this year at 48 - at the same time my Total T...

I've been on TRT since May 2016. I'm currently on a three-month break to reassess some things and am trying to educate myself so that I can hopefully have better results if I have to get back on (which is looking increasingly likely). I have low SHBG (currently around 18 NMOL/L, but as low as...

I’m a low shbg guy and was a patient of dr crislers for years we tried everything we could for my low t levels except transdermals. Currently I’m at 211 total t. I have low shbg. 12-15. I did horrible on all kinds of injection protocols. I stayed away from gel because of small child and another...

Hi, I am a low SHBG guy who has managed to increased it to around 14-15 while on TRT. It has been years trying to fine tune my protocol and after several lab tests and anaztrozole dosing, I have confirmed I feel best when my E2 is around 10ish. At that level my libido is very good, no bloating...

I'm around 700 natural T due to high shbg-60ish, and e2 is low 16-19. Would a low dose of T cyp keep me from shutting down my natural T? My thinking is that the extra T would push down shbg, then e2 might slowly increase to mid 20s without a shutdown. I have been experimenting with T and had a...

Guys that have low SHBG, what protocols have you used and what is your SHBG? I’m a low SHBG guy myself (11) prior to starting TRT and have tried ED @20mg and it still put my free over the top and E2 out of control. Just thought we could all share in one post what all we’ve tried and the results.

When I started trt my SHBG was 51 on a range of 19.3-76.4. My trough T has settled around 850-900 with a free T of 28-33. One peculiar thing is while my T has stabilized at a consistent place, SHBG keeps dropping. My last 3 labs were 37, 32, now 28. While trough total T was 876, 842, 883...

Hi, How many of you guys noticted lowered SHBG after starting TRT? I am most curious about people who had high-ish SHBG before taking testosterone. For me the drop was almost 50%.

I am high shbg, consistently over 55-65 (range 15-55) I am currently on 40 mg test 2x per week and 360 iu hcg 3x per week. I am getting very inconsistent sleep and feeling up/down throughout the week. I know high shbg typically go with larger, single injections but I’m worried that even more...

My SHBG is on the lower side at around 25. Total T is 650 trough days and E2 around 45. I currently inject 50mg test C two times a week (Tuesdays and Fridays) It has been mentioned on here in the past that I may benefit from an EOD schedule due to my low-normal SHBG. How do I calculate the...

I only seem to get libido and good/random erections during a protocol change, I have reduced my dosage several times and each time I get good libido in week 2 or 3 and then it dissapears. I am a daily low shbg injector. Has anyone dealt with this and how did you rectify it? Theory #1. it was...