low shbg

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  1. E

    Any new studies on low SHBG?

    I've been gone for a while but anything new with low SHBG? Any drugs in production that boost SHBG? Any new reasons why SHBG could be low? Any new low sHBG TRT protocols? Did ERO here finally get fixed up lol?
  2. M

    Low SHBG and anxiety?

    I know there’s a handful of cases of which starting trt has increased anxiety. I have had bouts of anxiety while on trt and will admit I’m still trying get dialed in. I know estrogen levels play a role being high or low is reported for anxiety, thyroid levels as well. In Dr. Crislers book he...
  3. C

    Switched to EOD and feeling worst

    Guys, As some of you know, I recently changed protocols from weekly injections to every 3.5 days. That change was a pretty drastic decision on my part but I almost immediately felt the benefits of it and stayed the course for seven weeks before drawing blood the day before next injection...
  4. C

    Will I benefit more if I switch to EOD

    I wanted to start another thread so not to get off topic with another thread I started. About 8 weeks ago I switched to 50mg of test every 3.5 days and feel pretty good on that protocol but feel there is room for Improvement. On this protocol I have not needed any AI’s which is one of the main...
  5. Systemlord

    Everyday TRT protocol dosing suggestions?

    It's been several weeks now since I added anastrozole .125 to my TRT protocol and I'm an over-responder and attempting to dose anastrozole seems like a losing battle, I've tried 1/4 of a .125 EOD which ends with my feeling terrible after only a week. I went 10 days without any AI, days two and...
  6. O

    Testosterone and Anastrozole starting dose for ED injections

    Can some of you knowledge gentleman help me formulate a starting dose for ED TRT injections. I am low SHBG, high free T, and high estrogen guy. Really stuck on how much test and anastrozole I should begin with given my situation.
  7. B

    New to T/HCG - Some Questions

    Hey guys, I'm not sure if this is the correct place for this but I thought I'd try to get some feedback on my situation. I've experimented some form of hormone replacement in the past: Pellets - expensive and the Dr. seemed to be about $$$/Too difficult to keep up with Clomid - higher T numbers...
  8. C

    Low SHBG

    I am looking for advice about my current regimen. I’m 42 years old and have been on trt for one year. I’m on 200 mg per week of test cyp along with 1.5 mg arimidex per week. My latest blood test was a few weeks ago and my results were 841 total testosterone with 22 for estradiol. My SHBG is...
  9. T

    5 months into TRT, Low SHBG, Very high Free T, Struggling to find a solution.

    Hello respected members, My age is 31 years and i have just completed 5 months of my TRT. Its been a struggle from the very start because i am a low SHBG guy(14.5 nmol/l). Previously I have tried different protocols like, 50 mg E 3.5 D Labwork T =721, E2 =42(non sensitive) 60 mg E 3.5 D...
  10. M

    Part of the Low SHBG Club and trying to dial in my protocol

    I'm a healthy 41 year old guy and in good shape, training BJJ and doing kettlebells 6 days/week. I started TRT this past February with Test C 100mg IM weekly after experiencing low T symptoms for several months. Pre TRT labs: TT 498, TF 14, SHBG 18. No E2 was drawn. After 5 weeks I had noticed...
  11. T

    Low SHBH means more free Test, So why TRT?

    When i started my TRT my initial total Test were 250-300 ng/dl and it was giving me classical low T symptoms. At that stage i had an SHBG of 19.8 to start with ( TRT lowered it to 14.5). But the confusion here is that when i had 300 total test before TRT i still had low T symptoms, BUT my SHBG...
  12. T

    I really need help !!! 12 weeks and depressed/stuck due to low shbg.

    I am 31 years old and 12 weeks into TRT. Please help me as i am really confused and stuck after my low shbg test came out last week. I am just kind of stuck at 12 th week. Seems like so much things revolving in my head at this stage. So it is best if i give you what i have done so far. I had...
  13. S

    Optimal TRT Strategy for low SHBG guys; SSRI effects; HCG vs. T injections effect on polycythemia

    Hi everyone, I've been reading here for a little over a year and I've found this site most educational. Thank you to Nelson for all the informative material on this website (I also enjoyed your book which I bought on Amazon) and for everyone else here who contributes information and shares...
  14. E

    Low SHBG: T Gel along with Injected T has Helped Somewhat

    As many members already know, my 5+ years of TRT benefits on a scale of 1 to 10 with 10 the best, have been a 1 at best. (I am not exaggerating) I have genetically low SHBG and its the hand that I have been dealt, so I have been trying anything that I can think of to try to help. The latest...
  15. Vince Carter

    E2 levels for low SHBG guys

    Prompted by a reply from Dr Saya: "As a side note, your E2 is lower than we like, but with the somewhat low SHBG you will have a higher free estradiol (same as a higher free testosterone) at any given total E2 level. Translation...the E2 is a bit low, but not as low as it appears on the...
  16. Gianluca Bonetti

    low SHBG guy, free T high, too much medication or SHBG creates imbalances?

    I have been wondering, since last conversation with Doc. if I actually I'm using too much Testosterone medication, the low SHBG confuses me a bit, before talking to doc I had always thought that to feel well TT would be the number to look at, I was wrong, Free T would be the testosterone ready...
  17. E

    LOW SHBG increasing

    My SHBG was at 4 last year, I got lots of blood work done except for Cholesterol. My liver numbers were in range, kind of higher side but never expected anything to be wrong. I was frustrated because everything was perfect. my A1C and thyroid numbers were perfect. That's when I did some more...
  18. E

    LOW SHBG not due to ANYTHING

    Blood work, didn't eat for 10 hours prior... My liver is fine too SHBG 6 (11 - 80) TSH 1.79 (0.45 - 5.1) T3, Free 3.9 (2.8 - 5.3) T4, Free 1.1 (0.8 - 2.2) Hemogolobin A1c 4.8% (4.0 - 5.6%) Estimated Avg Glucose 91 <154
  19. Nelson Vergel

    Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans

    Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans Andreas Peter1, Konstantinos Kantartzis1, Jürgen Machann2, Fritz Schick2, Harald Staiger1, Fausto Machicao1, Erwin Schleicher1, Andreas Fritsche1, Hans-Ulrich Häring1 and Norbert Stefan1 1Department of...
  20. Nelson Vergel

    People with lower SHBG and Vitamin D have fatty liver

    Combined Association of Vitamin D and Sex Hormone Binding Globulin With Nonalcoholic Fatty Liver Disease in Men and Postmenopausal Women: A Cross-Sectional Study. Wang N, et al. Medicine (Baltimore). 2016. Abstract This study aimed to explore the combined associations of 25(OH)-vitamin D...
  21. E

    TRT has been underwhelming for 4+ years - Low SHBG

    TRT for me has always been underwhelming even though my blood work is fine, I eat well and exercise 5 to 6 days a week. Libido was far better when I had low T than it has even been since. Tri-mix works, but with my low libido I don't really care much about having sex. No appreciable muscle gain...
  22. P

    SHBG low and free testosterone hight! and low vitamin D

    Witam wszystkich! SHBG i wolny testosteron niska wysoko&#347;&#263;, co robi&#263;? mniej SHBG mniej wolnego testosteronu, co jest nie tak? Przepraszam angielski
  23. V

    How can one increase SHBG when it is too low?

    I've been having some serious problems with my liver's low output of SHBG. Instead of increasing and decreasing the level like it is supposed to, my liver produces one tiny amount that does not change regardless of testosterone or estrogen levels. This leads to horrible, horrible over...
  24. Okian

    Low SHBG ! Good or bad?

    Found this article which says .. '' low SHBG is often a sign of many of the worst chronic diseases that we face in modern, civlized societies. 1. Obesity and Being Overweight. Low SHBG is associated with obesity. [1] The reason is probably due to a loss of insulin sensitivity as we'll...
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