hypogonadism

This gives us an OPTIMIZATION WINDOW of 11.8-15.9 ng/dL * over 20 years of the Millennium's clinical observation of patients we have identified that patients within this upper-mid quartile range demonstrate better energy, enhanced cognitive performance, improved metabolic stability and better...

* This narrative review integrates randomized and real‑world evidence on TRT‑associated AF, AKI, and PE, translates these signals into practical guidance for patient selection and safety monitoring, and outlines key methodological and mechanistic priorities for future research. In contemporary...

In this episode of Better Edge, Robert Brannigan, MD, president of the American Society for Reproductive Medicine (ASRM), discusses key updates from ASRM’s 2026 committee opinion on fertility preservation. Dr. Brannigan outlines what urologists should know about early identification, rapid...

In this episode, Shalin Shah, CEO of Marius Pharmaceuticals and a passionate advocate for testosterone education, shares insights on the misunderstood hormone that impacts both men and women. We dive into myths, testing protocols, treatment options, and the importance of early diagnosis for...

* The survey found that the most commonly reported symptoms over the past year (among those tested) included low energy or fatigue (48%), poor sleep (47%), reduced motivation (34%), low sex drive (28%), mood changes or irritability (27%), brain fog (26%), weight gain (26%), and reduced muscle...

* We devised a formula to calculate predicted total testosterone concentrations, based on meta-analyses of individual participant data from 21,074 men, aged 17-99 years, from nine cohort studies in Australia, Europe and North America of community-dwelling men with testosterone measured using...

* Dr. Jessica Colon-Franco is inspired by providing answers to physicians and patients using mass spectrometry. Dr. Jessica Colon-Franco is the Section Head of Clinical Biochemistry and Medical Director of the Special Chemistry Laboratory at Cleveland Clinic. Her clinical laboratory...

https://www.hhs.gov/press-room/fda-requests-updates-testosterone-therapy-labeling.html The U.S. Department of Health and Human Services, through the U.S. Food and Drug Administration (FDA), announced today that it is requesting updates to the prescribing information for testosterone...

Must listen here! Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost...

Powerhouse in the field! In this episode, Dr. Brandon and Dr. Morgentaler welcome Dr. Abdulmaged Traish, world-renowned hormone researcher and professor emeritus at Boston University, to talk about his incredible journey from growing up in a poor village with no electricity or running...

19:11 Why Enclomiphene Is So Unpredictable * the response is widely variable! Enclomiphene has quietly become one of the most prescribed men's health medications in America. It's marketed as the perfect alternative to testosterone replacement therapy (TRT): an oral medication that increases...

In this episode, Dr. Kelly Casperson is joined by urologist and men's health expert Dr. Helen Bernie to discuss why testosterone may be one of the most overlooked biomarkers in medicine. They dive into the surprising links between testosterone, diabetes, cardiovascular disease, osteoporosis...

I have been hammering this home on the forum over the years! Again the only way to know where your FT truly sits is to have it tested using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG! * This case highlights a critical diagnostic pitfall...

* We studied 394 men aged 22–76 years with primary (n=132), secondary (n=96), or functional (n=166) hypogonadism treated for up to 7 years with T-gel (1–3 actuations/day; n=168), TU 1000 mg intramuscularly every 10–14 weeks (n=142), or hCG 1500 IU subcutaneously twice weekly (n=84). *...

* We evaluated, for the first time in humans, whether chronic subcutaneous (SC) administration of kisspeptin-10 (KP10) can sustain gonadotropin secretion without desensitization. * This study provides the first evidence that chronic SC KP-10 administration can sustain gonadotropin secretion in...

https://endo2026.endocrine.org/searchGlobal.asp Background Exogenous estradiol (E2) may be prescribed for transgender females and menopausal women. Automated E2 immunoassays are widely used but bias often exists when compared to mass spectrometry (LC-MS) methods. Lack of assay...

https://endo2026.endocrine.org/searchGlobal.asp Introduction The association between circulating testosterone (T) levels and male sexual function was found to be stronger for free T than for total T. However, most studies have relied on calculated free T rather than directly measured...

Dr. Arthur Burnett discusses the way in which men traditionally have approached their health and talks about manners in which they may reframe their thinking.

Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in...

Erectile dysfunction is a very common condition in sexual medicine, but recognizing the symptoms and finding the right treatment isn't always easy. How do you know where to turn? Ask a Sexpert! In this video, Dr. Helen Bernie unpacks the common causes and symptoms of ED, as well as the various...

Born for this! https://www.renalandurologynews.com/features/mohit-khera-testosterone-therapy-for-men/ https://www.excelmale.com/threads/once-weekly-hcg-helps-preserve-fertility-in-men-on-testosterone-therapy-largest-study-yet.34086/

https://canadianhealthcarenetwork.ca/new-drug-jatenzo-oral-testosterone-replacement-therapy

My neck of the woods. One of the heavyweights in the field! Been at it for decades! Presented by: Dr. Shehzad Basaria Objectives: • To understand the Physiology of the Hypothalamic-Pituitary-Gondal Axis • To become familiar with various Etiologies of Male Hypogonadism •...

You've watched him pull away and wondered if something is actually wrong with his body — and you were right to wonder. Dr. Arthur Burnett, Johns Hopkins urologist, breaks down exactly what testosterone does (and doesn't) do for men's drive, erections, and mood — and why a basic blood test isn't...

In this episode of Pearls & Perspectives, Amy Pearlman, MD, is joined by Larry I. Lipschultz, MD, to discuss the growing interest in peptides, including their potential applications in men’s health, evolving regulatory landscape, and what urologists need to know as patient demand continues to...

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Good afternoon, I've been on TRT for little over 3 years and have tried every protocol under the sun, without ANY success. I am now in a phase where I realize I might need professional help, so if anyone has any online doctors that they would recommend and are ok with me doing UGL, please let...

* Immunoassays show acceptable accuracy for total T but are unreliable for free T measurement [19,20]. * As previously noted, the main limitation of free T evaluation in clinical practice is the poor accuracy of the available immunoassay methods [19]. To address this issue, several...

Join us for a live AMA on male fertility and sperm health! Urologist Dr. Andrew Sun (Urology Partners of North Texas) and reproductive endocrinologist Dr. Noorhasan (CCRM DFW) are teaming up to answer your questions — no topic off limits. From semen analysis and lifestyle factors to...

* Overall, the available evidence suggests that TRT may provide clinically meaningful improvements in mood for hypogonadal men, particularly those with low baseline testosterone and coexisting depressive symptoms. However, current data do not support its routine use as an antidepressant therapy...

* Each speaker presented compelling arguments supporting different testosterone delivery systems, illustrating that no single therapy is universally ideal for every patient. * Importantly, the session reinforced that the true “winner” of the debate was ultimately the patient. Rather than...