hypogonadism

19:11 Why Enclomiphene Is So Unpredictable * the response is widely variable! Enclomiphene has quietly become one of the most prescribed men's health medications in America. It's marketed as the perfect alternative to testosterone replacement therapy (TRT): an oral medication that increases...

In this episode, Dr. Kelly Casperson is joined by urologist and men's health expert Dr. Helen Bernie to discuss why testosterone may be one of the most overlooked biomarkers in medicine. They dive into the surprising links between testosterone, diabetes, cardiovascular disease, osteoporosis...

I have been hammering this home on the forum over the years! Again the only way to know where your FT truly sits is to have it tested using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG! * This case highlights a critical diagnostic pitfall...

* We studied 394 men aged 22–76 years with primary (n=132), secondary (n=96), or functional (n=166) hypogonadism treated for up to 7 years with T-gel (1–3 actuations/day; n=168), TU 1000 mg intramuscularly every 10–14 weeks (n=142), or hCG 1500 IU subcutaneously twice weekly (n=84). *...

* We evaluated, for the first time in humans, whether chronic subcutaneous (SC) administration of kisspeptin-10 (KP10) can sustain gonadotropin secretion without desensitization. * This study provides the first evidence that chronic SC KP-10 administration can sustain gonadotropin secretion in...

https://endo2026.endocrine.org/searchGlobal.asp Background Exogenous estradiol (E2) may be prescribed for transgender females and menopausal women. Automated E2 immunoassays are widely used but bias often exists when compared to mass spectrometry (LC-MS) methods. Lack of assay...

https://endo2026.endocrine.org/searchGlobal.asp Introduction The association between circulating testosterone (T) levels and male sexual function was found to be stronger for free T than for total T. However, most studies have relied on calculated free T rather than directly measured...

Dr. Arthur Burnett discusses the way in which men traditionally have approached their health and talks about manners in which they may reframe their thinking.

Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in...

Erectile dysfunction is a very common condition in sexual medicine, but recognizing the symptoms and finding the right treatment isn't always easy. How do you know where to turn? Ask a Sexpert! In this video, Dr. Helen Bernie unpacks the common causes and symptoms of ED, as well as the various...

Born for this! https://www.renalandurologynews.com/features/mohit-khera-testosterone-therapy-for-men/ https://www.excelmale.com/threads/once-weekly-hcg-helps-preserve-fertility-in-men-on-testosterone-therapy-largest-study-yet.34086/

https://canadianhealthcarenetwork.ca/new-drug-jatenzo-oral-testosterone-replacement-therapy

My neck of the woods. One of the heavyweights in the field! Been at it for decades! Presented by: Dr. Shehzad Basaria Objectives: • To understand the Physiology of the Hypothalamic-Pituitary-Gondal Axis • To become familiar with various Etiologies of Male Hypogonadism •...

You've watched him pull away and wondered if something is actually wrong with his body — and you were right to wonder. Dr. Arthur Burnett, Johns Hopkins urologist, breaks down exactly what testosterone does (and doesn't) do for men's drive, erections, and mood — and why a basic blood test isn't...

In this episode of Pearls & Perspectives, Amy Pearlman, MD, is joined by Larry I. Lipschultz, MD, to discuss the growing interest in peptides, including their potential applications in men’s health, evolving regulatory landscape, and what urologists need to know as patient demand continues to...

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Good afternoon, I've been on TRT for little over 3 years and have tried every protocol under the sun, without ANY success. I am now in a phase where I realize I might need professional help, so if anyone has any online doctors that they would recommend and are ok with me doing UGL, please let...

* Immunoassays show acceptable accuracy for total T but are unreliable for free T measurement [19,20]. * As previously noted, the main limitation of free T evaluation in clinical practice is the poor accuracy of the available immunoassay methods [19]. To address this issue, several...

Join us for a live AMA on male fertility and sperm health! Urologist Dr. Andrew Sun (Urology Partners of North Texas) and reproductive endocrinologist Dr. Noorhasan (CCRM DFW) are teaming up to answer your questions — no topic off limits. From semen analysis and lifestyle factors to...

* Overall, the available evidence suggests that TRT may provide clinically meaningful improvements in mood for hypogonadal men, particularly those with low baseline testosterone and coexisting depressive symptoms. However, current data do not support its routine use as an antidepressant therapy...

* Each speaker presented compelling arguments supporting different testosterone delivery systems, illustrating that no single therapy is universally ideal for every patient. * Importantly, the session reinforced that the true “winner” of the debate was ultimately the patient. Rather than...

Curated By Nelson Vergel | ExcelMale.com | Updated May 2026 Most men assume their penis will stay exactly as they remember it from their 20s. Then, somewhere in their 40s or 50s, things start to feel different. The erections are not quite as firm, morning wood has become less reliable, and a...

Justin Dubin, M.D. Urologist Director of Men’s Sexual Health Baptist Health Miami Cancer Institute

15:01 - Diagnosis, Assessment and Evaluation Male factor infertility accounts for nearly half of all infertility cases, yet male evaluation is often delayed or overlooked. In this episode of BackTable Urology, Dr. Robert Brannigan joins guest host Dr. Catherine Nam to unpack the 2024...

https://www.urologytimes.com/view/fda-grants-clearance-to-total-testosterone-assay The FDA has granted clearance to Revvity’s automated chemiluminescence immunoassay (ChLIA) for total testosterone measurement.1 The assay is designed to support diagnostic testing for androgen-related disorders...

Listen closely Dr/ Khera hitting the nail on the head here! T is a threshold hormone! Set-points ya dig! 31:15- 35:34 * The risks of chasing supraphysiological levels Most people don’t take their health seriously until something goes wrong. In this conversation with Dr Mohit Khera, we...

Another one under the belt for Dr. Bhasin! https://edhub.ama-assn.org/jn-learning/audio-player/19061825 Interview with Shalender Bhasin, MBBS, author of Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism: A Randomized Clinical Trial, and Peter C. Albertsen, MD, author...

https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2848537#google_vignette

No one should be using/elying on the known to be inaccurate direct immunoassay! Speakers: Jessica Colon-Franco, Ph.D., Cleveland Clinic; Leslie Farris, Ph.D., Cleveland Clinic Accurate assessment of free testosterone (FT) is essential in evaluating androgen...

https://mariuspharma.com/news/marius-pharmaceuticals-announces-key-leadership-expansion-and-launch-of-marius-ai-positioning-the-company-as-the-first-ai-native-pharmaceutical-company/ Raleigh, N.C., (May 7th, 2026) – Marius Pharmaceuticals, Inc., the makers of KYZATREX® (testosterone...

Shalin Shah explains how testosterone serves as a key biomarker for overall health and outlines common symptoms that indicate testing is needed: including fatigue, muscle loss, and decreased libido. He emphasizes that while lifestyle factors like diet, sleep, and exercise are foundational...