hypogonadism

  1. madman

    When to Switch your Patients T therapy

    As usual dropping some gems here!
  2. madman

    Tailoring T Therapy For Fertility and Cardiometabolic Patients

  3. madman

    Oral T Dosing and Lab Strategies

  4. madman

    Treatment of Symptomatic Male Hypogonadism with New Oral Testosterone Therapies: A Comparative Review of Jatenzo, Tlando, and Kyzatrex

    https://www.mdpi.com/2305-6320/13/1/1# Abstract Symptomatic male hypogonadism, defined by low serum testosterone with associated clinical symptoms, is increasingly treated with testosterone replacement therapy. Traditional oral formulations were limited by hepatotoxicity and poor...
  5. Nelson Vergel

    The doctor who overturned medicine’s fear of testosterone

    The first thing Abraham Morgentaler learned about testosterone is that it’s a brain hormone. It was in a lab at Harvard, while an undergraduate in the late 1970s, where he had this realization: A castrated male lizard put in a cage with a female would not perform its mating ritual and would be...
  6. madman

    The complications of multi-drug TRT (hCG; AIs; SERMs; 5ARIs)

    All those dime a dozen run of the mill T-clinics! High dosed T off the hop with an AI thrown in to boot LMFAO! * He explains that medications such as anastrozole, hCG, clomiphene, and enclomiphene—tools used thoughtfully in academic urology for specific indications—are now often bundled...
  7. madman

    Guidance on the use of oral TU : background, clinical considerations, and best practices

    When it comes to elevated hematocrit everyone is still so caught up on peak T levels! As I have been preaching for years on here running too high a trough/steady-state FT will have a big impact here! * While the precise mechanism underlying secondary polycythemia in the setting of TTh is still...
  8. madman

    The male hormone reset: how GLP-1RAs, lifestyle and testosterone transform obesity-linked problems

    Figure 1. Comparative overview of therapeutic approaches for male hypogonadism and metabolic dysfunction. The figure summarizes the key advantages and disadvantages of three main management modalities: GLP-1 receptor agonists (GLP-1 RAs), lifestyle modification (diet and exercise), and...
  9. madman

    Could Testosterone Therapy Protect Against Developing Prostate Cancer?

    In this episode, Dr. Brandon and Dr. Morgentaler talk about how emerging research suggests testosterone therapy may not only be safe but could actually help protect against aggressive prostate cancer, while also touching on practical approaches to maintaining sexual connection at midlife...
  10. madman

    Mohit Khera, MD, recaps key takeaways from FDA panel on TRT for men

    https://www.urologytimes.com/view/mohit-khera-md-recaps-key-takeaways-from-fda-panel-on-trt-for-men Mohit Khera, MD, MBA, MPH, recaps key takeaways from an FDA expert panel discussion on testosterone replacement therapy for men. In a recent interview with Urology Times®, Mohit Khera, MD, MBA...
  11. madman

    Own Your Testosterone with Natesto®

    https://www.natesto.com/ Save on NATESTO® With Eligible, commercially insured patients may pay as little as $25 per month*, per claim maximums apply. THE NATESTO® SAVINGS PROGRAM IS NOT HEALTH INSURANCE. *Manufacturer Terms: The Natesto Savings Program is not health insurance. Program...
  12. madman

    Testosterone Therapy: TT/Free T; Safety (CVD, PCa; Erythrocytosis); Fertility

    https://onlinelibrary.wiley.com/doi/10.1002/tre.70016 Abstract Testosterone replacement therapy has evolved significantly in recent years, driven by high-quality clinical evidence and expanded treatment options. The 2023 TRAVERSE trial provided definitive cardiovascular safety data, leading...
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