Nelson Vergel

Nelson Vergel

Nelson Vergel

Key Historical Failures and Lessons Learned from Attempts to Get a Testosterone Product FDA-Approved for Women
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FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
Melatonin's Role in Reproductive Health and Fertility
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Melatonin's Role in Reproductive Health and Fertility Executive Summary Melatonin (N-acetyl-5-methoxytryptamine), a neurohormone primarily known for regulating circadian rhythms, demonstrates profound and multifaceted effects on male and female...
hCG Plus TRT Testicular & Fertility Restoration Protocol
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Hey guys, what do you think I am missing in the downloadable attached PDF? This attached document synthesizes key findings on the use of Human Chorionic Gonadotropin (hCG) in men, either as an adjunct to Testosterone Replacement Therapy (TRT)...
HCG Use in Men on TRT or as Monotherapy: Over 200 Questions and Answers
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I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...
HCG, Clomid, and Anastrozole Use in Male Infertility
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Starting a family with a partner that you love is one of the most magical and exciting experiences that you will ever encounter. It is also daunting and very intimidating, but ultimately, becoming a parent will change you for the better. Sadly...
Practical Clinical Summary on Testosterone Therapy in Women
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Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological...
How Anabolic Agents Can Save Your Muscles: One Man's Journey from Death Sentence to Thriving at 66
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The story of how testosterone therapy and anabolic agents helped transform HIV treatment and what it means for men's health today. By Rafael Zara A Death Sentence That Changed Everything Nelson Vergel was just 24 years old when doctors...
https://www.defymedical.com/get-started/.
Options for Delayed or Absent Orgasms Despite Stimulation in Men
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Briefing: Male Delayed Orgasm and Anorgasmia Executive Summary This document synthesizes current knowledge on male Delayed Orgasm (DO) and Anorgasmia (AO), complex and often underreported sexual dysfunctions with a significant impact on quality...
Do statins affect erections in men?
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Question: Do statins affect erections in men? Answer: The science on statins and sexual function is inconclusive, but it does appear that taking a statin may sometimes affect a person's sex life. Researchers looked at statin use and sexual...
The Relationship Between Testosterone Therapy and Atrial Fibrillation: A U-Shaped Curve Hypothesis
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The Relationship Between Testosterone Therapy and Atrial Fibrillation: A U-Shaped Curve Hypothesis Executive Summary An analysis of clinical research on testosterone therapy and cardiovascular health reveals a complex, non-linear relationship...
PCT After Anabolics: Clomid versus hCG + Clomid
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Objectives To evaluate the clinical necessity and optimal pharmacological strategy for post-cycle therapy (PCT) in recreational anabolic-androgenic steroid (AAS) users with normal pre-cycle reproductive profiles. Subjects and Methods This...
Best HCG Dose for Men on TRT: Two Studies That Used HCG with Testosterone
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Note:HCG mimics LH but it is not LH and it's not picked up by the LH blood test. In fact, it suppresses LH like endogeneous testosterone does. But the amazing thing that the study below found is that HCG can increase sperm production and quality...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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